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Warren C.W. Chan
IBBME and CCBR
University of Toronto
Toronto, Ontario, Canada

About this book

In this edited book, we highlight the central players in the Bionanotechnology field, which are the nanostructures and biomolecules. The book starts by describing how nanostructures are synthesized and by describing the wide variety of nanostructures available for biological research and applications. Also shown are the techniques used to synthesize a wide variety of biological molecules. Next, there is a focus on the assembly of nanostructures with biological molecules, which could lead to the design of multi-functional nanosystems. In the following chapters, examples of the unique properties of nanostructures are provided along with the current applications of these nanostructures in biology and medicine. Some applications include the use of gold nanoparticles in diagnostic applications, quantum dots and silica nanoparticles for imaging, and liposomes for drug delivery. In the final chapters of the book, the toxicity of nanostructures are described. This book provides broad examples of current developments in Bionanotechnology research and would be an excellent introduction to the field.

Table of contents

SECTION I. NANOSTRUCTURE AND BIOMOLECULE SYNTHESIS

1. Synthetic Strategies to Size and Shape Controlled Nanocrystals
and Nanocrystal Heterostructures
P. Davide Cozzoli and Liberato Manna

2. Current Approaches for Engineering Proteins with Diverse
Biological Properties
Isaac T.S. Li, Elizabeth Pham and Kevin Truong

SECTION II. APPLICATIONS OF NANOSTRUCTURES

3. Past, Present, and Future of Gold Nanoparticles
Travis Jennings and Geoffrey Strouse

4. Multi-Functional Gold Nanoparticles for Drug Delivery
Gang Han, Partha Ghosh and Vincent M. Rotello

5. Quantum Dots for Cancer Molecular Imaging
Xiaohu Gao and Shivang R. Dave

6. Carbon Nanostructures as a New High-Performance Platform for MR
Molecular Imaging
Keith B. Hartman and Lon J. Wilson

7. Magnetic Nanoparticle Assisted Molecular MR Imaging
Young-wook Jun, Jung-tak Jang and Jinwoo Cheon

8. Patterning Metallic Nanoparticles by DNA Scaffolds
Rahul Chhabra, Jaswinder Sharma, Yan Liu and Hao Yan

9. Liposomes in Biology and Medicine
Reto A. Schwendener

10. Fluorescent Nanoparticle for Bacteria and DNA Detection
Wenjun Zhao, Lin Wang and Weihong Tan

11. Dendrimer 101
Lajos P. Balogh

SECTION III. TOXICITY OF NANOSTRUCTURES

12. Quantum Dots and Other Fluorescent Nanoparticles: Quo Vadis in the Cell?
Dusica Maysinger and Jasmina Lovri

13. Toxicity Studies of Fullerenes and Derivatives
Jelena Kolosnjaj, Henri Szwarc and Fathi Moussa

14. Toxicity Studies of Carbon Nanotubes
Jelena Kolosnjaj, Henri Szwarc and Fathi Moussa