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Programmed Cell Death in Protozoa


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José Manuel Pérez Martín
Centro de Biologia Molecular "Severo Ochoa" (CSIC-UAM)
Universidad Autonoma de Madrid

This book is co-published with Springer.

Please click here to purchase this book at the Springer site.

ISBN: 978-0-387-76716-1
Pub date: 2007-12-03
182 pages
54 figures
4 tables
7 color pages

About this book

Under the name of programmed cell death (PCD) are included diverse molecular mechanism of cell suicide which play an essential role in the development of multicellular organisms. The best known PCD mechanism in multicellular organisms is called apoptosis. However, recent studies indicate that PCD is also present in protozoa and unicellular eukaryotes. The eleven chapters of this book give the reader a comprehensive update of the progress in the understanding of the mechanisms of PCD in protozoa. The chapters have been written by experts in this field of research and are arranged following an evolutionary point of view starting with PCD in protists and ending with PCD in ciliated protozoa.

Table of contents

1. Programmed Cell Death in Protozoa: An Evolutionary Point of View.
The Example of Kinetoplastid Parasites
Miguel A. Fuertes, Paul A. Nguewa, Josefina Castilla, Carlos Alonso
and José Manuel Pérez Martín

2. Programmed Cell Death in Protists without Mitochondria: The Missing Link
Claude-Olivier Sarde and Alberto Roseto

3. Programmed Cell Death and Trypanosomatids: A Brief Review
Maria de Nazaré C. Soeiro and Elen M. de Souza

4. Programmed Cell Death in African Trypanosomes
Katherine Figarella, Néstor L. Uzcátegui, Viola Denninger, Susan Welburn
and Michael Duszenko

5. Molecular Analysis of Programmed Cell Death by DNA Topoisomerase Inhibitors
in Kinetoplastid Parasite Leishmania
Nilkantha Sen, Bijoylaxmi Banerjee and Hemanta K. Majumder

6. DNA Metallo-Intercalators with Leishmanicidal Activity
Maribel Navarro, Gonzalo Visbal and Edgar Marchán

7. Programmed Cell Death during Malaria Parasite Infection of the Vertebrate Host
and Mosquito Vector
Luke A. Baton, Emma Warr, Seth A. Hoffman and George Dimopoulos

8. In Search of Atropos’ Scissors: Severing the Life-Thread of Plasmodium
Marcel Deponte

9. Cell Death in Trichomonads
Marlene Benchimol

10. Programmed Cell Death and the Enteric Protozoan Parasite Blastocystis hominis:
Perspectives and Prospects
Kevin S.W. Tan

11. Programmed Cell Death in Dinoflagellates
María Segovia

12. Programmed Nuclear Death and Other Apoptotic-Like Phenomena
in Ciliated Protozoa
Ana Martín González, Silvia Díaz, Andrea Gallego and Juan C. Gutiérrez