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Lipid A in Cancer Therapy


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Jean-François Jeannin
Université Bourgogne

This book will be published in December of 2008

List price: TBA



ISBN: TBA
Pub date: 2008-12-01


Table of contents

Planned List of Topics

1. Introduction
J.F. Jeannin

2. Lipid A structures and chemical synthesis
S. Kusumoto

3. Conformation and supramolecular structure of lipid A
Klaus Brandenburg and Ulrich Seydel

4. Interactions between lipid A and serum protein
J. Andrä, T. Gutsmann, M. Mueller and A.B. Schromm

5. The lipid A receptors
K. Takeda

6. Lipid A receptor TLR4-mediated signaling pathways
M. Yamamoto and S. Akira

7. Lipid-A induced physiopathological responses
N. Sassi, A. Bettaieb and J.F. Jeannin

8. Lipid A-mediated tolerance in cancer therapy
C.E. Rockwell, D.C. Morison and N. Qureshi

9. Lipid A in cancer therapies: Preclinical results
D. Reisser

10. Monophosphoryl lipid A (MPL) as an adjuvant for anticancer vaccines:
Clinical results
C.W. Cluff

11. Lipid A in cancer therapies: Clinical results
M. Bardou

12. Conclusions
J.F. Jeannin