Email this

Print this

Spyros Papageorgiou
Institute of Biology, NRC 'Demokritos'
Athens, Greece

About this book

The study of Hox genes is crucial not only in exploring the enigma of homeosis but also in understanding normal development at the fundamental molecular level. "Hox Gene Expression" starts with the amazing discovery of the homeobox twenty-three years ago and follows the exciting path thereafter of a series of breakthroughs in Genetics, Development and Evolution. It deals with homeotic genes- their evolution, structure, normal and abnormal function. Researchers and graduate students in Biology and Medicine will benefit from this integrated overview of Hox gene activities.

Table of contents

1. The Homeobox as a Key for Understanding the Principles of the Genetic
Control of Development
Walter J. Gehring

2. Expression of Hox Genes in the Nervous System of Vertebrates
Christof Nolte and Robb Krumlauf

3. The Hox Gene Network in Vertebrate Limb Development
Cheryll Tickle

4. Evolution of Hox Gene Clusters
David E.K. Ferrier

5. Evolutionary Genomics of Hox Gene Clusters
Sonja J. Prohaska, Peter F. Stadler and Günter P. Wagner

6. Chromatin and the Control of Hox Gene Expression
Laila Kobrossy and Mark Featherstone

7. Homeobox-Containing Genes in Limb Regeneration
David M. Gardiner and Susan V. Bryant

8. HOX Genes and Stem Cells
Mina Gouti and Anthony Gavalas

9. Deregulation of the HOX Gene Network and Cancer
Clemente Cillo

Appendix–Hypothesis: Pulling Forces Acting on Hox Gene Clusters
Cause Expression Collinearity
Spyros Papageorgiou