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Lipocalins


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Bo Åkerström
University of Lund

Niels Borregaard
Granulocyte Research Laboratory

Darren R. Flower
The Jenner Institute

Jean-Philippe Salier
University of Rouen

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ISBN: 978-1-58706-297-1
Pub date: 2006-06-08
204 pages
45 figures
15 tables


About this book

Less than a decade has elapsed since the publication in 2000 of the first anthology devoted to lipocalins (Biochim Biophys Acta 1482, 2000), and only a few years since the first Lipocalin International Symposium in Copenhagen in 2003 (Benzon Symposium no. 50 “The Lipocalin Protein Superfamily,” Copenhagen, 2003) and the introduction of a public lipocalin website (http://www.jenner.ac.uk/lipocalins.htm). In spite of all these recent joint actions from the lipocalin community, the need for another anthology has been expressed. Many new exciting publications have been issued during the past five years, partially outdating the 2000 BBA lipocalin anthology. Likewise, the three events mentioned above have undoubtedly had a positive effect upon lipocalin research and the exchange of research information. As a result the community of lipocalin researchers is highly motivated to continue such pan-lipocalin activities. Several of the chapters in this volume are reviews of groups of lipocalins with a similar phylogenetic or tissue distribution (Chapters 4-6, 12 and 13). Furthermore, two chapters discuss the evolutionary and structural relationships between the lipocalins (Chapters 2 and 3) and the penultimate three chapters are treatises on themes in lipocalin research: receptors, allergy, and clinical diagnosis (Chapters 14-16); the final chapter discusses how lipocalin research might go in future.

Table of contents

1. Lipocalins: An Introduction
Bo Åkerström, Niels Borregaard, Darren R. Flower and Jean-Philippe Salier

2. Lipocalin Genes and Their Evolutionary History
Diego Sanchez, María D. Ganfornina, Gabriel Gutierrez, Anne-Christine Gauthier-Jauneau, Jean-Loup Risler and Jean-Philippe Salier

3. The Lipocalin Protein Family: Protein Sequence, Structure and Relationship
to the Calycin Superfamily
Maria D. Ganfornina, Diego Sanchez, Lesley H. Greene and Darren R. Flower

4. Bacterial Lipocalins: Origin, Structure, and Function
Russell E. Bishop, Christian Cambillau, Gilbert G. Privé, Derek Hsi, Desiree Tillo and Elisabeth R.M. Tillier

5. Plant Lipocalins
Jean-Benoit F. Charron and Fathey Sarhan

6. Lipocalins in Arthropoda: Diversification and Functional Explorations
María D. Ganfornina, Hartmut Kayser and Diego Sanchez

7. Retinol Binding Protein and Its Interaction with Transthyretin
Marcia E. Newcomer and David E. Ong

8. Siderocalins
Roland K. Strong

9. Lipocalin-Type Prostaglandin D Synthase as an Enzymic Lipocalin
Yoshihiro Urade, Naomi Eguchi and Osamu Hayaishi

10. a1-Microglobulin
Bo Åkerström and Lennart Lögdberg

11. Glycodelin: A Lipocalin with Diverse Glycoform-Dependent Actions
Markku Seppälä, Hannu Koistinen, Riitta Koistinen, Philip C.N. Chiu, and William S.B. Yeung

12. Functional Aspects of b-Lactoglobulin, Major Urinary Protein and Odorant-Binding Protein
Andrea Cavaggioni, Paolo Pelosi, Stephen G. Edwards and Lindsay Sawyer

13. The Plasma Lipocalins a1-Acid Glycoprotein, Apolipoprotein D, Apolipoprotein M and Complement Protein C8g
Willem van Dijk, Sonia Do Carmo, Eric Rassart, Björn Dahlbäck and James M. Sodetz

14. Lipocalin Receptors: Into the Spotlight
Brian J. Burke, Clara Redondo, Bernhard Redl and John B.C. Findlay

15. Important Mammalian Respiratory Allergens Are Lipocalins
Tuomas Virtanen and Rauno Mäntyjärvi

16. Lipocalins in Clinical Medicine
Lennart Lögdberg and Bo Åkerström

17. The Lipocalin Protein Family: Perspectives for Future Research
Darren R. Flower and Arne Skerra