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Immune Mechanisms in Inflammatory
Bowel Disease


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Richard S. Blumberg
Brigham and Women's Hospital
Harvard Massachusetts, U.S.A.

Markus F. Neurath
Johannes-Gutenberg-University
Mainz, Germany

This book is co-published with Springer.

Please click here to purchase this book at the Springer site.

ISBN: 978-0-387-30831-9
Pub date: 2006-02-23
248 pages
34 figures
27 tables

About this book

Immune Mechanisms in Inflammatory Bowel Disease is a highly concise update of the most recent advances in the fields of immunobiology, genetics and microbiology related to Inflammatory Bowel Disease. This book broadly treats the topics that lead to understanding of the pathogenesis of this disease in an organized, systematic approach.

Table of contents

1. Structure and Function of the Gut Mucosal Immune System
Reinhard Pabst and Hermann J. Rothkötter

2. Functional Aspects of the Mucosal Immune System
Cathryn Nagler-Anderson

3. Recent Progress in Inflammatory Bowel Disease Genetics
Judy H. Cho

4. Microbial and Dietary Factors in the Pathogenesis of Chronic, Immune-Mediated Intestinal Inflammation
R. Balfour Sartor

5. Experimental Models of Mucosal Inflammation
Warren Strober and Ivan J. Fuss

6. Overview of Role of the Immune System in the Pathogenesis of Inflammatory Bowel Disease
Thomas T. MacDonald and Giovanni Monteleone

7. The Role of the Epithelial Barrier in Inflammatory Bowel Disease
Edward E.S. Nieuwenhuis and Richard S. Blumberg

8. Involvement of Dendritic Cells in the Pathogenesis of Inflammatory Bowel Disease
Francisco Leon, Lesley E. Smythies, Phillip D. Smith and Brian L. Kelsall

9. Alterations of T Lymphocytes in Inflammatory Bowel Diseases
Charles O. Elson, Yingzi Cong and Casey T. Weaver

10. The B-Cell System in Inflammatory Bowel Disease
Per Brandtzaeg, Hege S. Carlsen and Trond S. Halstensen

11. Alterations of Mesenchymal and Endothelial Cells in Inflammatory Bowel Diseases
Claudio Fiocchi, Kenji Ina, Silvio Danese, André Z.A. Leite and Jon D. Vogel

12. Role of Mast Cells and Eosinophils in Neuroimmune Interactions Regulating Mucosal Inflammation in Inflammatory Bowel Disease
Stephan C. Bischoff and Thomas Gebhardt

13. Multiparameter Analysis of Immunogenetic Mechanisms in Clinical Diagnosis and Management of Inflammatory Bowel Disease
Jonathan Braun and Stephan R. Targan

14. The Role of Probiotics and Antibiotics in Regulating Mucosal Inflammation
Rainer Duchmann

15. From Immunogenic Mechanisms to Novel Therapeutic Approaches in Inflammatory Bowel Disease
Martin H. Holtmann and Markus F. Neurath