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Eukaryotic DNA Damage Surveillance and Repair


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Keith W. Caldecott
University of Sussex


ISBN: 978-0-306-47987-8
Pub date: 2004-04-28
172 pages
28 figures
5 tables
5 color pages


Table of contents

1. DNA Damage Surveillance in Saccharomyces cerevisiae
Geraldine W-L. Toh, Stefano Maffini and Noel F. Lowndes

2. Mammalian Base Excision Repair
Grigory L. Dianov, Sarah L. Allinson, Helen Budworth and Kate Sleeth

3. Detection and Repair of DNA Single-Strand Breaks
Keith W. Caldecott

4. The Detection and Repair of Nucleotide Damage and Coupling to Major
Cellular Regulatory Processes in Mammalian Cells
James E. Cleaver

5. Mammalian DNA Mismatch Repair
Helen M.R. Robinson and Robert Brown

6. Origin, Recognition, Signaling and Repair of DNA Double-Strand Breaks
in Mammalian Cells
Larry H. Thompson and Charles L. Limoli

7. The Mechanism of DNA Non-Homologous End-Joining: Lessons Learned
from Biophysical, Biochemical and Cellular Studies
P.A. Jeggo