Email this

Print this

Matti Weckstrom
University of Oulu
Oulu, Findland

Pasi Tavi
University of Oulu
Oulu, Findland

About this book

This book takes a multidisciplinary approach to the topic. The chapters depict the many faces of mechanotransduction, from membrane and ion channel level to mechanics, biochemical signaling and regulation via hormone systems. Cardiac Mechanotransduction is of interest to basic life sciences, like physiology, biochemistry and pharmacology, but also to clinicians working with heart-related problems, such as cardiologists and internists.

Table of contents

1. The Mechanosensory Heart: A Multidisciplinary Approach
Matti Weckström and Pasi Tavi

2. Origin of Mechanotransduction: Stretch-Activated Ion Channels
Clive M. Baumgarten

3. The Role of the Sarcomere and Cytoskeleton
in Cardiac Mechanotransduction
Sarah C. Calaghan and Ed White

4. Mechanoelectric Transduction/Feedback Physiology and Pathophysiology
Max J. Lab

5. Mechanotransduction in Cardiac Remodeling and Heart Failure
Jeffrey H. Omens, Andrew D. McCulloch and Ilka Lorenzen-Schmidt

6. Second Messenger Systems Involved in Heart Mechanotransduction
Hiroshi Hasegawa, Hiroyuki Takano, Yunzeng Zou, Hiroshi Akazawa and Issei Komuro

7. The Role of Adrenoceptors in Mechanotransduction
Klaus-Dieter Schlüter, Hans Michael Piper and Sibylle Wenzel

8. Intracellular Signaling Through Protein Kinases
in Cardiac Mechanotransduction
Peter H. Sugden

9. Mechanotransduction of the Endocrine Heart Paracrine
and Intracellular Regulation of B-Type Natriuretic Peptide Synthesis
Sampsa Pikkarainen, Heikki Tokola and Heikki Ruskoaho