Email this

Print this

Marek Los
Universität Münster

Henning Walczak
Deutsches Krebsforschungszentrum

Table of contents

1. The Caspase Family
Mohamed Lamkanfi, Wim Declercq, Bart Depuydt, Michael Kalai,
Xavier Saelens and Peter Vandenabeele

2. Caspase Cascades in Apoptosis
Colin Adrain, Emma M. Creagh and Seamus J. Martin

3. Caspase Activation at the TNF-R Family Members Death
Inducing Signaling Complexes (DISCs)
Martin R. Sprick and Henning Walczak

4. Mitochondrial/Apoptosome Dependent Activation of Caspases
Kelvin Cain

5. Modulation of Caspase Activity by Cellular Inhibitors
Klaus W. Wagner, Badry D. Bursulaya and Quinn L. Deveraux

6. Virus-Encoded Caspase Inhibitors
Grant McFadden and Richard W. Moyer

7. Apoptosis Dependent and Independent Functions of Caspases
Alicia Algeciras-Schimnich, Bryan C. Barnhart and Marcus E. Peter

8. The Role of Caspases in Modulation of Cytokines and other Molecules
in Apoptosis and Inflammation
Harald Loppnow, Krzysztof Guzik and Juliusz Pryjma

9. Caspases, Bcl-2 Family Proteins and Other Components of the Death
Machinery: Their Role in the Regulation of the Immune Response
Marc Pellegrini and Andreas Strasser

10. Learning from Deficiency: Gene Targeting of Caspases
Timothy S. Zheng

11. Caspase Activation in Cancer Therapy
Simone Fulda, Klaus-Michael Debatin

12. In Situ Activation of Caspases Revealed by Affinity Labeling
Their Enzymatic Sites
Jerzy Grabarek and Zbigniew Darzynkiewicz

13. Other Methods of Caspase Activity Monitoring
Hubert Hug, Christof Burek and Marek Los

14. Caspases as Targets for Drug Development
Manuela Michalke, Anna Stepczynska, Malgorzata Burek,
Truc Nguyen Bui, Karin Loser, Krzysztof Krzemieniecki and Marek Los

15. Caspase-Independent Cell Death Mechanisms
Donat Kögel and Jochen H. M. Prehn