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Photoreceptors and Calcium


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Wolfgang Baehr
University of Utah

Krzysztof Palczewski
University of Washington


ISBN: 978-0-306-47415-6
Pub date: 2002-11-01
632 pages


Table of contents

Calcium and phototransduction

The calcium gradient along the rod outer segment

The time course of light adaptation in vertebrate retinal rods

S-modulin

Ca2+-dependent control of rhodopsin phosphorylation: recoverin and rhodopsin kinase

Recoverin and rhodopsin kinase

Pathological roles of recoverin in cancer-associated retinopathy

RGS9-1 phosphorylation and Ca2+

Phosphorylation by cyclin-dependent protein kinase 5 of the regulatory subunit (Pg) of retinal cGMP phosphodiesterase (PDE6): its implications in phototransduction

Centrins, a novel group of Ca2+-binding proteins in vertebrate photoreceptor cells

Tuning outer segment Ca2+ homeostasis to phototransduction in rods and cones

Regulation of the rod photoreceptor cyclic nucleotide-gated channel

Ca2+ channels in the RPE

The retinal rod and cone Na+/Ca2+-K+ exchangers

The complex of cGMP-gated channel and Na+/Ca2+-K+ exchanger in rod photoreceptors

Regulation of voltage-sensitive Ca2+ channels in bipolar cells in divalent cations and polyamines

Site-directed and natural mutations in studying functional domains in guanylyl cyclase activating proteins (GCAPs)

Calmodulin and Ca2+-binding proteins (CaBPs): variations on a theme

GCAPs: Ca2+-sensitive regulators of retGC

Structure and membrane-targeting mechanism of retinal Ca2+-binding proteins, recoverin and GCAP-2

Target recognition of guanylate cyclase by guanylate cyclase-activating proteins

Mouse models to study GCAP functions in intact photoreceptors

Calcium-dependent activation of guanylate cyclase by S100b

The role of cadherins in Ca2+-mediated cell adhesion and inherited photoreceptor degeneration

Guanylate cyclase-activating proteins, guanylate cyclase and disease

Using mutant mice to study the role of voltage-gated calcium channels in the retina

Caldendrins in the inner retina

Calcium channels at the photoreceptor synapse

On bipolar cells: following in the footsteps of phototransduction

Ca2+ regulation of Drosophila phototransduction

Simultaneous roles for Ca2+ excitation and adaptation of Limulus ventral photoreceptors

Calcium homeostasis in fly photoreceptor cells

Photoreceptor degeneration and Ca2+ influx through light-activated channels of Drosophila

The TRP calcium channel and retinal degeneration