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Molecular Mechanisms of Pathogenesis in Chagas Disease


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JohnM. Kelly
London School of Hygiene and Tropical Medicine


ISBN: 978-0-306-47849-9
Pub date: 2003-08-12
172 pages


Table of contents

Activation of bradykinin-receptors by Trypanosoma cruzi : a role for cruzipain in vascular pathology
Julio Scharfstein

Genetic diversity of Trypanosoma cruzi and the epidemiology of Chagas disease
Michael Miles

The Trypanosoma cruzi surface mucin coat: structure, regulation of expression and relevance in the host-parasite relationship
Alberto Carlos C. Frasch

Glycosylphosphatidylinositol anchors structure and role in the host proinflammatory response
Igor Almeida

Impact of polyclonal lymphocyte responses on parasite evasion and persistence
Paola Minoprio

Oxidative defence mechanisms in Trypanosoma cruzi
John Kelly, Shane Wilkinson

The effect of Ca2+ signalling on the invasion process
Roberto Docampo

From the nucleus to the surface in Trypanosoma cruzi
Sergio Schenkman

The role of NO in the pathogenesis of Trypanosoma cruzi infection
Joao Santana Silva

The protokine concept
Miercio Pereira

The brute-force approach to parasitology; The Trypanosoma cruzi genome project
Bjorn Andersson