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Theodore Hupp
University of Aberdeen

Ayeda Ayed
University of Toronto

This book will be published in December of 2008

List price: TBA



ISBN: TBA
Pub date: 2008-12-31

Table of contents

Tumour suppressor genes
Kay Macleod

Cancer progression models
Kennth Kinzler and Reid

Tumour-causing viruses
Ed Harlow

Genome instability
Thea Tylsty

p53 protein structure
Alan Fircht

Biochemical regulation of p53
Ted Hupp

The AT signal transduction paradigm
Graeme Smith

p53 signaling lesions
Ljungman

MDM2-dependent degradation
Ronai

p53-dependent apoptosis
M. Oren

The model p53 mediator: p21WAF1
Ball

Killer Genes
Karen Vousden

Activation of p53
Galivanova

MDM2 and p14ARF
David Lane

Chaperones
F. Neckers

Small molecule screening
Pfizer

Gene therapy
F. McCormick