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Adaptive Systems in Drug Design


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Gisbert Schneider
Wolfgang - Goethe - Universität Frankfurt

Sung-Sau So
Hoffmann-LaRoche

List price: $139.00
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ISBN: 978-1-58706-059-5
Pub date: 2002-10-01
169 pages
55 figures
18 tables


About this book

A brief history of drug design presented to make clear that there are fashions in this important field and that they change rather rapidly. This is due in part to the fact that the way that a new paradigm is accepted in a drug company often does not depend on its scientific merit alone.

Table of contents

A Conceptual Framework
Gisbert Schneider and Sung-Sau So

Analysis of Chemical Space
Gisbert Schneider and Sung-Sau So

Modeling Structure-Activity Relationships
Gisbert Schneider and Sung-Sau So

Prediction of Drug-Like Properties
Gisbert Schneider and Sung-Sau So

Evolutionary De Novo Design
Gisbert Schneider and Sung-Sau So