Semaphorins: Receptor and Intracellular Signaling Mechanisms
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R. Jeroen Pasterkamp
This book is co-published with Springer.
Please click here to purchase this book at the Springer site. ISBN: 978-0-387-70955-0 Pub date: 2007-05-24 148 pages 35 figures 4 tables |
About this bookThis book is intended to provide a representative survey of recent progress on research devoted to semaphorins with an emphasis on receptor and intracellular signaling mechanisms. The first four chapters address several of the key families of cytosolic signaling cues implicated in semaphorin signaling (including CRMPs, small GTPases, protein kinases, and MICALs). The following three chapters cover the intracellular and extracellular factors that modulate semaphorin signaling (various cytosolic cues, Ig superfamily cell adhesion molecules, and proteoglycans). Finally, the last four chapters review recent progress in our understanding of how semaphorin signaling pathways may contribute to the development and disease of specific biological systems. |
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Table of contents1. The CRMP Family of Proteins and Their Role in Sema3A Signaling 2. GTPases in Semaphorin Signaling 3. Intracellular Kinases in Semaphorin Signaling 4. MICAL Flavoprotein Monooxygenases: Structure, Function and Role 5. Signaling of Secreted Semaphorins in Growth Cone Steering 6. Modulation of Semaphorin Signaling by Ig SuperFamily Cell Adhesion Molecules 7. Proteoglycans as Modulators of Axon Guidance Cue Function 8. Semaphorin Signals in Cell Adhesion and Cell Migration: Functional Role
9. Semaphorin Signaling during Cardiac Development 10. Semaphorin Signaling in Vascular and Tumor Biology 11. Semaphorin Signaling in the Immune System |
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