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Ischemia-Reperfusion Injury in Cardiac Surgery


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Friedhelm Beyersdorf
Department of Surgery

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ISBN: 978-1-58706-002-1
Pub date: 2000-05-01
227 pages
51 figures
20 tables


About this book

Cardiac surgery is associated with ischemia and reperfusion injury for most of the operations performed. During the last decades, major improvements have been done in reducing both ischemic and reperfusion injury and therefore improving the quality of the operation. This book summarizes the newest developments in this field. In addition, specific comments are made concerning the surgical application of the fields in all kinds of operation, including routine cases as well as complex procedures. The reader will gain a detailed insight regarding how to protect patients best during routine cardiac procedures (coronary artery revascularization and valve replacement) as well as prolonged, technically demanding operations  

Table of contents

Harnessing the Cardioprotective Potential of Nitric Oxide in Nonsurgical and Surgical Ischemic-Reperfusion Injury

The Cellular Basis of Immediate Lethal Reperfusion Injury

Apoptosis in Ischemia: Reperfusion Injury

Changes in Myocardial Gene Expression Following Ischemia and Reperfusion

The NO-Donor L-Arginine Reduces the Reperfusion Injury after Heart Transplantation

Sodium-Proton Exchange Inhibition as a Novel Strategy for Myocardial Protection

Metabolic Support for the Heart During Ischemia and Reperfusion: Role of Amino Acids

Metabolic and Antioxidant Support with Amino Acids

Methods to Reduce Ischemia/Reperfusion Injury PICSO

Ischemic Preconditioning From Bench to Bedside

Away from Ischemic Preconditioning and Towards Pharmacological Preconditioning

Intravenous Metabolic Support with GIK (Glucose-Insulin-Potassium) and Amino Acids in Cardiac Surgery

Cold/Tepid Cardioplegia

Surgical Techniques for Warm Blood Cardioplegia

Interrupting Warm Blood Cardioplegia

Myocardial Protection Strategies in Routine Coronary and Valve Operations

Acute Myocardial Infarction and Cardiogenic Shock

Protection Strategies in Reoperations

Protection Strategies for Heart Transplantation