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Cytokines and Chemokines in Autoimmune Disease


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Pere Santamaria
University of Calgary


ISBN: 978-0-306-47693-8
Pub date: 2002-11-01
316 pages
16 figures
9 tables


About this book

This book describes the mechanisms of action of cytokines and chemokines in the major autoimmune diseases such as diabetes mellitus, multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus and inflammatory bowel disease along with prospective treatment interventions.

Table of contents

Autoimmune diseases and cytokines: pathogenesis and therapy.
Pere Santamaria

Cytokines, chemokines, their receptors and their genes: an overview.
David J. Kelvin

Cytokine and cytokine receptor genes in the genetic susceptibility and resistance to autoimmunity.
Roland S. Liblau

Cytokines, lymphocyte homeostasis and self-tolerance.
Yiguang Chen

Cytokines as effector mechanisms of tissue destruction in autoimmunity.
Thomas W.H. Kay

Cytokines in the pathogenesis and treatment of experimental autoimmune encephalomyelitis and multiple sclerosis.
David O. Willenborg

Chemokines in experimental autoimmune encephalomyelitis and multiple sclerosis.
Trevor Owens

Cytokines in the pathogenesis of pancreatic islet graft desruction in autoimmune diabetes.
Alex Rabinovitch

Chemokines and cytokines in autoimmune diabetes.
Terry L. Delovitch

Cytokines in the pathogenesis of rheumatoid arthritis and collagen-induced arthritis.
Erik Lubberts

Chemokines in rheumatoid arthritis
N. Karin

Cytokines and chemokines in virus-induced autoimmunity.
Matthias G. Von Herrath

Cytokines in the treatment and prevention of autoimmune responses.
Terry B. Strom

Cytokines and chemokines in human autoimmune skin disorders (SLE, pemphigus vulgaris).
Thomas Schwarz

Cytokines and chemokines in SLE.
Frederick A. Houssiau

Cytokines in the pathogenesis and treatment of inflammatory bowel disease.
Lothar Steidler