The Mitochondrial Free Radical Theory of Aging
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Aubrey D.N.J. de Grey
List price: $149.00 |
About this bookThe vast complexity of organismal degeneration with age has too often intimidated gerontologists into over-cautious interpretation of their results. Therefore, theories of mammalian aging have been too open and preliminary to underpin the design of medical interventions. This book breaks new ground in the effort to overcome that inertia, by providing a highly detailed and experimentally well-founded model of mammalian aging, together with analysis of the ways in which that model may be exploited to influence the rate of aging. It will benefit biologists, clinicians and the scientifically-minded laypersons alike, by giving a robust conceptual structure to compare with ongoing experimental and medical findings. |
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Table of contentsIntroduction An Introduction to Mitochondria An Introduction to Free Radicals An Introduction to Lipid Metabolism A Descriptive Introduction to Human Aging History of the Mitochondrial Free Radical Theory of Aging, 1954-1995 The Status of Gerontological Theory in 1995 The Search for How Mutant mtDNA Is Amplified The Search for How So Few Anaerobic Cells Cause So Much Oxidative Stress Frequently-Asked Questions A Challenge from Textbook Bioenergetics and Free Radical Chemistry Some Testable Predictions of MiFRA |
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