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Molecular Mechanisms
of Ataxia Telangiectasia


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Shamim I. Ahmad
Nottingham Trent University
Nottingham, England

This book will be published in December of 2008
Pre-publication price: $129.00
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ISBN: TBA
Pub date: 2008-12-31


Table of contents

Planned List of Topics

Preface
Shamim I. Ahmad

Clinical features excluding neurological disorders of Ataxia telangiectasia
A.M.R. Taylor

Mutations in the Ataxia telangiectasia mutated (ATM) gene
Akira Tachibana

Chromosomal instability in Ataxia telangiectasia
Luitpold Distel and Susann Neubauer

DNA damage and repair in Ataxia telangiectasia
Phillip B. Carpenter and Melissa Adams

Cell signalling in Ataxia telangiectasia
Tetsuo Nakajima

Cell cycle defects and apoptosis in Ataxia telangiectasia
Fred Bunz and Deborah Wilsker

Protein-protein interactions in Ataxia telangiectasia
Yue Zou and Steven Shell

Ataxia telangiectasia: An oxidative stress-related disease
Giovanni B. Pagano, Paolo Degan and Giuseppe Castello

Oncogenesis in Ataxia telangiectasia: Roles of ATM, p53, NF-kB and DDE recombination pathogenesis
D.H. Dreyfus

Animal models of Ataxia telangiectasia
Robert H. Schiestl

Ataxia telangiectasia and its overlap with Nigmegan breakage syndrome
and Ataxia-like disorders
Xiao Wei and Lindsay G. Ball