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Arieh Gertler
Institute of Biochemistry
The Hebrew University of Jerusalem

This book will be published in September of 2008
Pre-publication price: $129.00
ISBN: TBA
Pub date: 2008-09-01

Table of contents

Planned List of Topics

PART 1: MOLECULAR ASPECTS OF LEPTIN ACTION

Leptin signal transduction: A 2008 update
Walter Becker

Understanding leptin/leptin receptor interaction: A rational approach
for development of leptin antagonists
Frank Peelman, Lennart Zabeau and Jan Tavernier

Study of leptin:leptin receptor interaction by FRET and BRET
Julie Dam, Cyril Couturier and Ralf Jockers

PART 2: LEPTIN INVOLVEMENT IN PHYSIOLOGICAL AND PATHOLOGICAL PROCESSES

Is leptin a pro or anti-apoptotic agent?
Srujana Rayalam, Mary Anne Della-Fera and Clifton A. Baile

Leptin action in the gastrointestinal system
Sandra Guilmeau and Andre Bado

Leptin-a novel biomarker in breast and colorectal cancer
Eva Surmacz and Mariusz Koda

The role of leptin in cardiovascular physiology and pathology
Morris Karmazyn, Daniel M Purdham, Venkatesh Rajapurohitam Asad Zeidan

The role of leptin in bone development and growth
Efrat Monsonego Ornan and Michal Ben-Ami

Involvement of leptin in arterial hypertension
Jerzy Beltowski

Involvement of leptin in endometrial function
Carlos Simon and Ana Cervero

Potential use of leptin for treatment of lipodystrophy and related disorders
Angeline Chong, Elaine Cochran and Phillip Gorden

Use of anti-leptin or anti-leptin receptor antibodies as blockers
of immune response
Giuseppe Matarese and Veronica De Rosa

Use of leptin antagonists as anti-inflammatory and anti fibrotic reagents
Eran Elinav, Zamir Halpern and Arieh Gertler

The role of leptin during the early post-natal period in imprinting later
metabolic responses
Mark H Vickers, Stefan O Krechowec, Peter Gluckman and Bernhard H Breier