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Table of Contents

15 January 2008

volume 7| issue 2



Extra Views

Ras nanoclusters: Combining digital and analog signaling

Angus Harding and John F. Hancock
Volume: 7 | Issue: 2 | Pages: 127 - 134

Niche players: Spermatogonial progenitors marked by GPR125

Marco Seandel, Ilaria Falciatori, Sergey V. Shmelkov, Jiyeon Kim, Daylon James and Shahin Rafii
Volume: 7 | Issue: 2 | Pages: 135 - 140

Mechanisms of mammalian polo-like kinase 1 (Plk1) localization: Self- versus non-self-priming

Kyung S. Lee, Jung-Eun Park, Young Hwi Kang, Wendy Zimmerman, Nak-Kyun Soung, Yeon-Sun Seong, Sahng-June Kwak and Raymond L. Erikson
Volume: 7 | Issue: 2 | Pages: 141 - 145

Control of the Cdc6 replication licensing factor in metazoa: the role of nuclear export and the CUL4 ubiquitin ligase

Jihyun Kim and Edward T. Kipreos
Volume: 7 | Issue: 2 | Pages: 146 - 150

What makes centromeric cohesion resistant to separase cleavage during meiosis I but not during meiosis II?

Juraj Gregan, Cornelia Rumpf, Zhang Li and Lubos Cipak
Volume: 7 | Issue: 2 | Pages: 151 - 153

Perspectives

p53 promoter selection: choosing between life and death

Sanjeev Das, Sarah A. Boswell, Stuart A. Aaronson and Sam W. Lee
Volume: 7 | Issue: 2 | Pages: 154 - 157

The common germline Arg72Pro polymorphism of p53 and increased longevity in humans

Stig E. Bojesen and Børge G. Nordestgaard
Volume: 7 | Issue: 2 | Pages: 158 - 163

Open Access Article


The Wip1 phosphatase and Mdm2: Cracking the “Wip” on p53 stability

Xiongbin Lu, Thuy-Ai Nguyen, Xinna Zhang and Lawrence A. Donehower
Volume: 7 | Issue: 2 | Pages: 164 - 168

MAP kinase p38 and its relation to T cell anergy and suppressor function of regulatory T cells

Henric S. Adler and Kerstin Steinbrink
Volume: 7 | Issue: 2 | Pages: 169 - 175

Environmental restrictions within tumor ecosystems select for a convergent, hypoxia-resistant phenotype of cancer stem cells

Massimo Olivotto and Persio Dello Sbarba
Volume: 7 | Issue: 2 | Pages: 176 - 187

Metastatic cancer stem cells: A new target for anti-cancer therapy?

Patrick C. Hermann, Stephan L. Huber and Christopher Heeschen
Volume: 7 | Issue: 2 | Pages: 188 - 193

TNF signaling gets FLIPped off: TNF-induced regulation of FLIP

Stuart A. Rushworth, Alison Taylor, Susana Langa and David J. MacEwan
Volume: 7 | Issue: 2 | Pages: 194 - 199

Review

Genetic Similarities Between Organogenesis and Tumorigenesis of the Lung

Scott Powers and David Mu
Volume: 7 | Issue: 2 | Pages: 200 - 204

Priority Report

Specific isoforms of p73 control the induction of cell death induced by the viral proteins, E1A or Apoptin

Poramaporn Klanrit, Marcella B. Flinterman, Edward W. Odell, Gerry Melino, Richard Killick, James S. Norris and Mahvash Tavassoli
Volume: 7 | Issue: 2 | Pages: 205 - 215

Reports

Basal c-Jun N-terminal kinases promote mitotic progression through histone H3 phosphorylation

Kyunghee Lee and Kiwon Song
Volume: 7 | Issue: 2 | Pages: 216 - 221

Specific inhibition of Mdm2-mediated neddylation by Tip60

Christoph Dohmesen, Max Koeppel and Matthias Dobbelstein
Volume: 7 | Issue: 2 | Pages: 222 - 231

Synergystic induction of HIF-1α transcriptional activity by hypoxia and lipopolysaccharide in macrophages

Zenghui Mi, Annamaria Rapisarda, Lynn Taylor, Alan Brooks, Mark Creighton-Gutteridge, Giovanni Melillo and Luigi Varesio
Volume: 7 | Issue: 2 | Pages: 232 - 241

Functional analyses of the cancer stem cell-like properties of human endometrial tumor initiating cells

Anne M. Friel, Petra A. Sergent, Christine Patnaude, Paul P. Szotek, Esther Oliva, David T. Scadden, Michael V. Seiden, Rosemary Foster and Bo R. Rueda
Volume: 7 | Issue: 2 | Pages: 242 - 249

Open Access Article


A transcriptional profiling meta-analysis reveals a core EWS-FLI gene expression signature

Jeffrey D. Hancock and Stephen L. Lessnick
Volume: 7 | Issue: 2 | Pages: 250 - 256

PI3K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27Kip1

Takafumi Nakao, Amy E. Geddis, Norma E. Fox and Kenneth Kaushansky
Volume: 7 | Issue: 2 | Pages: 257 - 266

Letter to the Editor

A new mitotic-cell specific monoclonal antibody

Martine Cazales, Muriel Quaranta, Valérie Lobjois, Denis Jullien, Talal Al Saati, Georges Delsol and Bernard Ducommun
Volume: 7 | Issue: 2 | Pages: 267 - 268

HSV-1 UL45 encodes a carbohydrate binding C-type lectin protein

Lucjan S. Wyrwicz, Krzysztof Ginalski and Leszek Rychlewski
Volume: 7 | Issue: 2 | Pages: 269 - 271