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Table of Contents

1 June 2008

volume 7| issue 11



Opinions and Viewpoints

Embryotic evolution: An ancient question, a new answer

Christian Schwabe
Volume: 7 | Issue: 11 | Pages: 1503 - 1506

Open Access Article



Extra Views

Cep192 and the generation of the mitotic spindle

Maria Ana Gomez-Ferreria and David J. Sharp
Volume: 7 | Issue: 11 | Pages: 1507 - 1510

(Un)expected roles of c-IAPs in apoptotic and NFκB signaling pathways

Eugene Varfolomeev and Domagoj Vucic
Volume: 7 | Issue: 11 | Pages: 1511 - 1521

USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A

Xiao-yong Zhang, Harla Pfeiffer, Alan Thorne and Steven B. McMahon
Volume: 7 | Issue: 11 | Pages: 1522 - 1524

TRAIL death receptors as tumor suppressors and drug targets

Niklas Finnberg and Wafik S. El-Deiry
Volume: 7 | Issue: 11 | Pages: 1525 - 1528

Open Access Article


Cancerous miRNAs and their regulation

Xu-Bao Shi, Clifford G. Tepper and Ralph W. deVere White
Volume: 7 | Issue: 11 | Pages: 1529 - 1538

Promoter-proximal Pol II: When stalling speeds things up

Sergei Nechaev and Karen Adelman
Volume: 7 | Issue: 11 | Pages: 1539 - 1544

Cell cycle control of microRNA-mediated translation regulation

Shobha Vasudevan, Yingchun Tong and Joan A. Steitz
Volume: 7 | Issue: 11 | Pages: 1545 - 1549

Sin3B: An essential regulator of chromatin modifications at E2F target promoters during cell cycle withdrawal

Kathryn B. Grandinetti and Gregory David
Volume: 7 | Issue: 11 | Pages: 1550 - 1554

Checkpoints meet the transcription at a novel histone milestone (H3-T11)

Midori Shimada and Makoto Nakanishi
Volume: 7 | Issue: 11 | Pages: 1555 - 1559

Perspectives

Understanding how kinase-targeted therapies work

Sabrina Arena and Alberto Bardelli
Volume: 7 | Issue: 11 | Pages: 1560 - 1563

Extracellular HSP90: Conquering the cell surface

Katerina Sidera and Evangelia Patsavoudi
Volume: 7 | Issue: 11 | Pages: 1564 - 1568

Interfering with protein-protein interactions: Potential for cancer therapy

Tomoyuki Tanaka and Terence H. Rabbitts
Volume: 7 | Issue: 11 | Pages: 1569 - 1574

Inferences and Hypotheses

Does the absence of ABCC6 (Multidrug Resistance Protein 6) in patients with Pseudoxanthoma elasticum prevent the liver from providing sufficient vitamin K to the periphery?

Piet Borst, Koen van de Wetering and Reinier Schlingemann
Volume: 7 | Issue: 11 | Pages: 1575 - 1579

Open Access Article



Brief Report

Identification and characterization of a novel Mdm2 splice variant acutely induced by the chemotherapeutic agents Adriamycin and Actinomycin D

Nathan H. Lents, Leroy W. Wheeler, Joseph J. Baldassare and Brian David Dynlacht
Volume: 7 | Issue: 11 | Pages: 1580 - 1586

Reports

Involvement of N-terminally truncated variants of p73, ΔTAp73, in head and neck squamous cell cancer: a comparison with p53 mutations

Laetitia Faridoni-Laurens, Sophie Tourpin, Samar Alsafadi, Michel Barrois, Stephane Temam, François Janot, Serge Koscielny, Jacques Bosq, Jean Bénard and Jean-Charles Ahomadegbe
Volume: 7 | Issue: 11 | Pages: 1587 - 1596

Functional independency between catalytic activity and subcellular targeting of Polo-like kinase-1: Phenotypes of ectopic overexpression of various mutants

Jae-Hoon Ji and Young-Joo Jang
Volume: 7 | Issue: 11 | Pages: 1597 - 1603

Elevated MDM2 boosts the apoptotic activity of p53-MDM2 binding inhibitors by facilitating MDMX degradation

Mingxuan Xia, Dejan Knezevic, Christian Tovar, Baoying Huang, David C. Heimbrook and Lyubomir T. Vassilev
Volume: 7 | Issue: 11 | Pages: 1604 - 1612

Midkine induces epithelial-mesenchymal transition through Notch2/Jak2-Stat3 signaling in human keratinocytes

Yiping Huang, Mohammad Obaidul Hoque, Feng Wu, Barry Trink, David Sidransky and Edward A. Ratovitski
Volume: 7 | Issue: 11 | Pages: 1613 - 1622

Genetic stability of senescence reverted cells: Genome reduction division of polyploidy cells, aneuploidy and neoplasia

Kirsten H. Walen
Volume: 7 | Issue: 11 | Pages: 1623 - 1629

Phenotype-defining functions of multiple non-coding RNA pathways

Gennadi V. Glinsky
Volume: 7 | Issue: 11 | Pages: 1630 - 1639

Open Access Article


ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer

Isabelle Mercier, Magalis Vuolo, Jean-Francois Jasmin, Christina M. Medina, Mark Williams, John M. Mariadason, Hong Qian, Xiaonan Xue, Richard G. Pestell, Michael P. Lisanti and Richard N. Kitsis
Volume: 7 | Issue: 11 | Pages: 1640 - 1647

Selective cytotoxicity of synthesized procyanidin 3-O-Galloylepicatechin-4b,8-3-O-galloylcatechin to human cancer cells

Min Kim, Xiaofang Wu, Insun Song, Maofu Fu, Seo-Hee Chang, Michael P. Lisanti and Richard G. Pestell
Volume: 7 | Issue: 11 | Pages: 1648 - 1657

Sex-specific microRNAome deregulation in the shielded bystander spleen of cranially exposed mice

Igor Koturbash, Franz J. Zemp, Kristy Kutanzi, Lidiya Luzhna, Jonathan Loree, Bryan Kolb and Olga Kovalchuk
Volume: 7 | Issue: 11 | Pages: 1658 - 1667

DNA damage-induced S phase arrest in human breast cancer depends on Chk1, but G2 arrest can occur independently of Chk1, Chk2 or MAPKAPK2

Wen-Hui Zhang, Alissa Poh, Andrew A. Fanous and Alan Eastman
Volume: 7 | Issue: 11 | Pages: 1668 - 1677

A global genomic view of MIF knockdown-mediated cell cycle arrest

Lingfeng Liu, Chaoneng Ji, Jinzhong Chen, Yao Li, Xuping Fu, Yi Xie, Shaohua Gu and Yumin Mao
Volume: 7 | Issue: 11 | Pages: 1678 - 1692