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Table of Contents

15 May 2008

volume 7| issue 10



Review of Concept

“Targeting the absence” and therapeutic engineering for cancer therapy

Mikhail V. Blagosklonny
Volume: 7 | Issue: 10 | Pages: 1307 - 1312

Open Access Article



Extra Views

Controlled rereplication at DNA replication origins

María Gómez
Volume: 7 | Issue: 10 | Pages: 1313 - 1314

Mechanism of relapse in pediatric acute lymphoblastic leukemia

Michelle J. Henderson, Seoyeon Choi, Alex H. Beesley, Rosemary Sutton, Nicola C. Venn, Glenn M. Marshall, Ursula R. Kee, Michelle Haber and Murray D. Norris
Volume: 7 | Issue: 10 | Pages: 1315 - 1320

Live cell imaging of XLF and XRCC4 reveals a novel view of protein assembly in the non-homologous end-joining pathway

Ken-ichi Yano and David J. Chen
Volume: 7 | Issue: 10 | Pages: 1321 - 1325

β-catenin takes a HIT

Otmar Huber and Jörg Weiske
Volume: 7 | Issue: 10 | Pages: 1326 - 1331

Explaining the preponderance of Kras mutations in human cancer: An isoform-specific function in stem cell expansion

Margaret P. Quinlan and Jeffrey Settleman
Volume: 7 | Issue: 10 | Pages: 1332 - 1335

Modulation of 14-3-3 interaction with phosphorylated histone H3 by combinatorial modification patterns

Stefan Winter, Wolfgang Fischle and Christian Seiser
Volume: 7 | Issue: 10 | Pages: 1336 - 1342

Perspectives

Control of pancreatic β-cell fate by insulin signaling: The sweet spot hypothesis

James D. Johnson and Emilyn U. Alejandro
Volume: 7 | Issue: 10 | Pages: 1343 - 1347

Unraveling estrogen action in osteoporosis

Susan A. Krum and Myles Brown
Volume: 7 | Issue: 10 | Pages: 1348 - 1352

How do real tumors become resistant to cisplatin?

Piet Borst, Sven Rottenberg and Jos Jonkers
Volume: 7 | Issue: 10 | Pages: 1353 - 1359

Open Access Article


Cancer stem cells: Models, mechanisms and implications for improved treatment

Jiangbing Zhou and Ying Zhang
Volume: 7 | Issue: 10 | Pages: 1360 - 1370

Cancer stem cells and survival pathways

Dolores Hambardzumyan, Oren J. Becher and Eric C. Holland
Volume: 7 | Issue: 10 | Pages: 1371 - 1378

Review

Inhale to survive, cycle or die? Carbon monoxide and cellular proliferation

Barbara Wegiel, Beek Y. Chin and Leo E. Otterbein
Volume: 7 | Issue: 10 | Pages: 1379 - 1384

Reports

PDGF/VEGF system activation and angiogenesis following initial post ovariectomy meningeal microvessel loss

Olga V. Glinskii, Tsghe W. Abraha, James R. Turk, Vladislav V. Glinsky and Virginia H. Huxley
Volume: 7 | Issue: 10 | Pages: 1385 - 1390

The CK2 phosphorylation of catalytic domain of Cdc34 modulates its activity at the G1 to S transition in Saccharomyces cerevisiae

Paola Coccetti, Farida Tripodi, Gabriella Tedeschi, Simona Nonnis, Oriano Marin, Sonia Fantinato, Claudia Cirulli, Marco Vanoni and Lilia Alberghina
Volume: 7 | Issue: 10 | Pages: 1391 - 1401

DNA Replication, cell cycle progression and the targeted gene repair reaction

Julia U. Engstrom and Eric B. Kmiec
Volume: 7 | Issue: 10 | Pages: 1402 - 1414

TIPT, a male germ cell-specific partner of TRF2, is chromatin-associated and interacts with HP1

Stefano Brancorsini, Irwin Davidson and Paolo Sassone-Corsi
Volume: 7 | Issue: 10 | Pages: 1415 - 1422

SET8 plays a role in controlling G1/S transition by blocking lysine acetylation in histone through binding to H4 N-terminal tail

Yinliang Yin, Vivian C. Yu, Guang Zhu and Donald C. Chang
Volume: 7 | Issue: 10 | Pages: 1423 - 1432

p14ARF is capable of promoting HIV-1 Tat degradation

Barbara Gargano, Marianna Fiorillo, Stefano Amente, Barbara Majello and Luigi Lania
Volume: 7 | Issue: 10 | Pages: 1433 - 1439

DNA replication in early S phase pauses near newly activated origins

Rebecca A. Frum, Paul D. Chastain II, Pingping Qu, Stephanie M. Cohen and David G. Kaufman
Volume: 7 | Issue: 10 | Pages: 1440 - 1448

CDK1 inhibitors antagonize the immediate apoptosis triggered by spindle disruption but promote apoptosis following the subsequent rereplication and abnormal mitosis

Ying Wai Chan, Hoi Tang Ma, Winnie Wong, Chui Chui Ho, Kin Fan On and Randy Y.C. Poon
Volume: 7 | Issue: 10 | Pages: 1449 - 1461

HOPS is an essential constituent of centrosome assembly

Stefania Pieroni, Maria Agnese Della Fazia, Marilena Castelli, Danilo Piobbico, Daniela Bartoli, Cinzia Brunacci, Marina Maria Bellet, Mariapia Viola-Magni and Giuseppe Servillo
Volume: 7 | Issue: 10 | Pages: 1462 - 1466

Analysis of DBC1 and its homologs suggests a potential mechanism for regulation of Sirtuin domain deacetylases by NAD metabolites

Vivek Anantharaman and L Aravind
Volume: 7 | Issue: 10 | Pages: 1467 - 1472

ZM 447439 inhibition of aurora kinase induces Hep2 cancer cell apoptosis in three-dimensional culture

Zi-Jie Long, Jie Xu, Min Yan, Jian-Gang Zhang, Zhong Guan, Da-Zhi Xu, Xian-Ren Wang, Jine Yao, Fei-Meng Zheng, Guo-Liang Chu, Jun-Xia Cao, Yi-xin Zeng and Quentin Liu
Volume: 7 | Issue: 10 | Pages: 1473 - 1479

Targeting Plk1 to chromosome arms and regulating chromosome compaction by the PICH ATPase

Mei Leng, Dario Besusso, Sung Yun Jung, Yi Wang and Jun Qin
Volume: 7 | Issue: 10 | Pages: 1480 - 1489

Oxidative stress induces cell cycle-dependent Mre11 recruitment, ATM and Chk2 activation and histone H2AX phosphorylation

Hong Zhao, Frank Traganos, Anthony P. Albino and Zbigniew Darzynkiewicz
Volume: 7 | Issue: 10 | Pages: 1490 - 1495

Letter to the Editor

Histone H4 acetylation during UV light induced G1 and S phase arrest of the cell cycle

Miglena Koprinarova and George Russev
Volume: 7 | Issue: 10 | Pages: 1496 - 1498