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Review
The Mitotic Spindle Matrix: A Fibro-Membranous Lamin Connection
Yixian Zheng and Ming-Ying Tsai
volume 5 | issue 20
15 october 2006Pages: 2345 - 2347
This is an open-access article
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The mitotic spindle apparatus has attracted the attention of cell biologists for decades. Whereas the main function of this microtubule-based system is to segregate chromosomes, spindle morphogenesis and chromosome segregation must also coordinate with the segregation of the whole cell. The finding that RanGTPase stimulates the assembly of a lamin B-containing membranous matrix in mitosis [1] may provide a connection between the segregation of mitotic chromosomes and the partitioning of membrane systems during cell division.
Authors
Yixian Zheng
Carnegie Institution of Washington and Howard Hughes Medical Institute, Baltimore, Maryland
Ming-Ying Tsai
Carnegie Institution of Washington and Howard Hughes Medical Institute, Baltimore, Maryland
This is an open-access article
Download PDFIf the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.