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Table of Contents

July 2008

volume 7| issue 7



Special Article

Evaluating the drug-target relationship between thymidylate synthase expression and tumor response to 5-fluorouracil: Is it time to move forward?

Shayna L. Showalter, Timothy N. Showalter, Agnes Witkiewicz, Robert Havens, Eugene P. Kennedy, Tomas Hucl, Scott E. Kern, Charles J. Yeo and Jonathan R. Brody
Volume: 7 | Issue: 7

Research Paper

Contrast enhanced MRI and intravital fluorescence microscopy indicate improved tumor microcirculation in highly vascularized melanomas upon short-term anti-VEGFR treatment

M.E. Eichhorn, S. Strieth, S. Luedemann, A. Kleespies, U. Noeth, A. Passon, G. Brix, K.-W. Jauch Jauch, C.J. Bruns and M. Dellian
Volume: 7 | Issue: 7

Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species

Jin-Jian Lu, Ling-Hua Meng, Yu-Jun Cai, Qin Chen, Lin-Jiang Tong, Li-Ping Lin and Jian Ding
Volume: 7 | Issue: 7

Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R)

Tijana Andjelkovic, Milica Pesic, Jasna Bankovic, Nikola Tanic, Ivanka D. Markovic and Sabera Ruzdijic
Volume: 7 | Issue: 7

Downregulation of c-jun results in apoptosis-mediated anti-osteosarcoma activity in an orthotopic model

Crispin R. Dass, Anna M. Friedhuber, Levon M. Khachigian, Dave E. Dunstan and Peter F. M. Choong
Volume: 7 | Issue: 7

A critical role of CCR7 in invasiveness and metastasis of SW620 colon cancer cell in vitro and in vivo

Shuyi Yu, Juping Duan, Zhiqun Zhou, Qiong Pang, Wuyang Ji , Ting Liu, Xiaowen He, Xinfa Liu and Yuxiang Chen
Volume: 7 | Issue: 7

Dexamethasone reduces tumor recurrence and metastasis after pancreatic tumor resection in SCID mice

Jan-Hendrik Egberts, Bodo Schniewind, Miriam Pätzold, Bastian Kettler, Jürgen Tepel, Holger Kalthoff and Anna Trauzold
Volume: 7 | Issue: 7

Survivin knockdown combined with apoptin overexpression inhibits cell growth significantly

Qin Liu, Hanjiang Fu, Ruiyun Xing, Yi Tie, Jie Zhu, Zhixian Sun and Xiaofei Zheng
Volume: 7 | Issue: 7

Stereomicroscopic fluorescence imaging of head and neck cancer xenografts targeting CD147

J. Robert Newman , John P. Gleysteen , Christopher F. Barañano , Jennifer R. Bremser , Jennifer R. Bremser , Wenyue Zhang, Kurt R. Zinn and Eben L. Rosenthal
Volume: 7 | Issue: 7

Involvement of PI3K/AKT/GSK3ß pathway in tetrandrine-induced G1 arrest and apoptosis

Xuan-li Chen, Kai-huan Ren, Hong-wei He and Rong-guang Shao
Volume: 7 | Issue: 7

Sustained ERK activation is involved in the kaempferol-induced apoptosis of breast cancer cells and is more evident under 3-D culture condition

Bong-Woo Kim, Eung-Ryoung Lee, Hye-Min Min, Hyo-Soon Jeong, Jae-Yeon Ahn, Jung-Hyun Kim, Hye-Yeon Choi, Hana Choi, Eun Young Kim, Se Pill Park and Ssang-Goo Cho
Volume: 7 | Issue: 7

Anti-ErbB4 targeted therapy combined with radiation therapy in prostate cancer: Results of in-vitro and in-vivo studies

AKIVA VEXLER, GHALIB LIDAWI, VERED LOEW, ITAY BARNEA, VICTORIYA KARAUSH, ALEXANDER SHTABSKY and RAMI BEN-YOSEF
Volume: 7 | Issue: 7

EphA2 overexpression promotes ovarian cancer growth

Chunhua Lu, Mian M.K. Shahzad , Hua Wang , Charles N. Landen, Seung W. Kim , Julie Allen , Alpa M. Nick, Nicholas Jennings , Michael S. Kinch , Menashe Bar-Eli and Anil K. Sood
Volume: 7 | Issue: 7

Remarkable enhancement of cytotoxicity of onconase and cepharanthine when used in combination on various tumor cell lines

Masamichi Ita, H. Dorota Halicka, Toshiki Tanaka, Akira Kurose, Barbara Ardelt, Kuslima Shogen and Zbigniew Darzynkiewicz
Volume: 7 | Issue: 7

IFN-α and IFN-λ differ in their antiproliferative effects and duration of JAK/STAT signaling activity

Stephen G. Maher, Faruk Sheikh, Anthony J. Scarzello, Ana L. Romero-Weaver, Darren P. Baker, Raymond P. Donnelly and Ana M. Gamero
Volume: 7 | Issue: 7

Pre-clinical evaluation and efficacy studies of a melanin-binding IgM antibody labeled with 188Re against experimental human metastatic melanoma in nude mice

E. Dadachova, E. Revskaya, M.A. Sesay, H. Damania, R. Boucher, R.S. Sellers, R.C. Howell, L. Burns, G.B. Thornton, A. Natarajan, G.R. Mirick, S.J. DeNardo, G.L. DeNardo and A. Casadevall
Volume: 7 | Issue: 7

Stable RNA interference of hexokinase II gene inhibits human colon cancer loVo cell growth in vitro and in vivo

Qiuping Peng , Qi Zhou , Daping Zhong , Feng Pan and Houjie Liang
Volume: 7 | Issue: 7

Serum levels of NF-κB and pro-inflammatory cytokines following administration of mucotoxic drugs

Richard M Logan, Andrea M Stringer, Joanne M Bowen, Rachel J Gibson, Stephen T Sonis and Dorothy M K Keefe
Volume: 7 | Issue: 7

Genome-wide profiling at methylated promoters in pancreatic adencarcinoma

Noriyuki Omura, Chung-Pin Li, Ang Li, Seung-Mo Hong, Kimberly Walter, Antonio Jimeno, Manuel Hidalgo and Michael Goggins
Volume: 7 | Issue: 7