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Table of Contents

March 2008

volume 7| issue 3



Editor's Corner


Volume: 7 | Issue: 3

Cover Image


Volume: 7 | Issue: 3

Review

Tumor-initiating stem cells in liver cancer

Shan Yong Yi and Ke Jun Nan Nan
Volume: 7 | Issue: 3 | Pages: 325 - 330

Journal Club

Genetic stability of tumor microenvironment

Matthew Danish, Tristan Sissung, Douglas K. Price and William D. Figg
Volume: 7 | Issue: 3 | Pages: 331 - 332

Clinical Study

Phase I single-dose study of intracavitary-administered Nimotuzumab labeled with 188-Re in adult recurrent high-grade glioma

Angel Casaco, Gerardo López, Iván García, José Arsenio Rodríguez, Ramsés Fernández, Javier Figueredo, Leonel Torres, Alejandro Perera Pintado, Juan Batista, René Leyva, Yamilé Peña, Zaida Amador, Addys González, Barbara Estupiñan, Marcos Coca, Abel Hernández, Miguel Puig, Marbelia Iglesias, Astrid Hernández, Mayra Ramos, Leyanis Rodriquez and Niurelkis Suarez
Volume: 7 | Issue: 3 | Pages: 333 - 339

BMI-1 autoantibody in serum as a new potential biomarker of nasopharyngeal carcinoma

Yong-Qing Tong, Bei Liu, Jian Huang, Yan Liu, Feng-Jie Guo, Guo-Hua Zhou, Ping-Li Xie, Yue-Hui Li, Jin-Yue Hu and Guan-Cheng Li
Volume: 7 | Issue: 3 | Pages: 340 - 344

Co-expression patterns of tumor-associated antigen genes by non-small cell lung carcinomas: Implications for immunotherapy

Vaios Karanikas, Stefanos Tsochas, Konstantinos Boukas, Theodora Kerenidi, Marianna Nakou, Jubrail Dahabreh, Theodoros Poularakis, Konstantinos I. Gourgoulianis and Anastasios E. Germenis
Volume: 7 | Issue: 3 | Pages: 345 - 352

Research Paper

Sensitive and quantitative detection of KRAS2 gene mutations in pancreatic duct juice differentiates patients with pancreatic cancer from chronic pancreatitis, potential for early detection

Chanjuan Shi, Noriyoshi Fukushima, Tadayoshi Abe, Yansong Bian, Li Hua, Brian J. Wendelburg, Charles J. Yeo, Ralph H. Hruban, Michael G. Goggins and James R. Eshleman
Volume: 7 | Issue: 3 | Pages: 353 - 360

Commentary

Shining the spotlight on shed kras in pancreatic cancer

Lorenzo Sempere and Murray Korc
Volume: 7 | Issue: 3 | Pages: 361 - 363

Research Paper

Differential response of human glioblastoma cell lines to combined camptothecin and ionizing radiation treatment

Cholpon S. Djuzenova, Teresa Güttler, Sabrina Berger, Astrid Katzer and Michael Flentje
Volume: 7 | Issue: 3 | Pages: 364 - 373

Commentary

Broken beyond repair: Damaging DNA in glioblastoma cells with radiation and camptothecin

Zbigniew Darzynkiewicz
Volume: 7 | Issue: 3 | Pages: 374 - 375

Research Paper

Synergy of pancratistatin and tamoxifen on breast cancer cells in inducing apoptosis by targeting mitochondria

Peter Siedlakowski, Amanda McLachlan-Burgess, Carly Griffin, Sridhar S. Tirumalai, James McNulty and Siyaram Pandey
Volume: 7 | Issue: 3 | Pages: 376 - 384

Commentary

Synergy of pancratistatin and tamoxifen in inducing apoptosis in breast cancer cells

Sidhartha Ray
Volume: 7 | Issue: 3 | Pages: 385 - 386

Research Paper

Synergistic effect of mTOR inhibitor rapamycin and fluorouracil in inducing apoptosis and cell senescence in hepatocarcinoma cells

Xinxin Bu, Chen Le, Fengqi Jia, Xianling Guo, Li Zhang, Mengchao Wu and Lixin Wei
Volume: 7 | Issue: 3 | Pages: 392 - 396

High-resolution analysis of genomic profiles of hepatocellular carcinoma cells with differential osteopontin expression

Bingsheng Sun, Jincai Wu, Ti Zhang and Changli Wang
Volume: 7 | Issue: 3 | Pages: 397 - 398

Commentary

A new trick for an old drug: mTOR inhibitor rapamycin augments the effect of fluorouracil on hepatocellular carcinoma by inducing cell senescence

Yufang Shi and David A. August
Volume: 7 | Issue: 3 | Pages: 397 - 398

Research Paper

Antibacterial, antifungal, and anticancer activities of volatile oils and extracts from stems, leaves, and flowers of Eucalyptus sideroxylon and Eucalyptus torquata

Hossam M. Ashour
Volume: 7 | Issue: 3 | Pages: 399 - 403

Cellular differentiation in three-dimensional lung cell cultures

Roger A. Vertrees, Joseph B. Zwischenberger, Paul J. Boor, Vselovod Popov, Maureen McCarthy and Thomas Goodwin
Volume: 7 | Issue: 3 | Pages: 405 - 412

Lack of ABC transporter autoinduction in mice following long-term exposure to imatinib

Erin R. Gardner, Alex Sparreboom, Jaap Verweij and William D. Figg
Volume: 7 | Issue: 3 | Pages: 412 - 415

Commentary

Transporter pumps and imatinib: A cause of pharmacokinetic resistance?

Heinz-Josef Klumpen , Chris Liddle and Howard Gurney
Volume: 7 | Issue: 3 | Pages: 416 - 418

Research Paper

Thymosin beta 4 is overexpressed in human pancreatic cancer cells and stimulates proinflammatory cytokine secretion and JNK activation

Yuqing Zhang, Louis W. Feurino, Qihui Zhai, Hao Wang, William E. Fisher, Changyi Chen, Qizhi Yao and Min Li
Volume: 7 | Issue: 3 | Pages: 419 - 423

Increased expression of cytoplasmic HuR in familial adenomatous polyposis

Lodewijk A.A. Brosens, Josbert J. Keller, Leena Pohjola, Caj Haglund, Folkert H. Morsink, Christine Iacobuzio-Donahue, Michael Goggins, Francis M. Giardiello, Ari Ristimäki and G. Johan A. Offerhaus
Volume: 7 | Issue: 3 | Pages: 424 - 427

Commentary

HuRrying colon cancer progression

Natalia A. Ignatenko and Eugene W. Gerner
Volume: 7 | Issue: 3 | Pages: 428 - 429

Research Paper

19-nor-1α,25-Dihydroxyvitamin D2 (Paricalcitol) inhibits the proliferation of human pancreatic cancer cells in vitro and in vivo

Gary G. Schwartz, Dawn Eads, Christine Naczki, Scott Northrup, Tai Chen and Constantinos Koumenis
Volume: 7 | Issue: 3 | Pages: 430 - 436

Commentary

Vitamin D for the treatment and prevention of pancreatic cancer.

Halcyon Skinner
Volume: 7 | Issue: 3 | Pages: 437 - 439

Research Paper

Tumor chemo-immunotherapy using gemcitabine and a synthetic dsRNA

Uyen M. Le, Nijaporn Yanasarn, Christiane V. Löhr, Kay A. Fischer and Zhengrong Cui
Volume: 7 | Issue: 3 | Pages: 440 - 447

Cancer gene therapy of adenovirus-mediated anti-4-1BB scFv in immunocompetent mice

Fang Liu, Qin Lu, Xun Ye, Chao Fang, Yi Zhao, Min Liang, Fang Hu, Andre Lieber and Hong-zhuan Chen
Volume: 7 | Issue: 3 | Pages: 448 - 453

A direct protein-protein interaction is involved in the suppression of β-catenin transcription by retinoid X receptor α in colorectal cancer cells

Anjia Han, Chang Tong, Dong Hu, Xiuli Bi and Wancai Yang
Volume: 7 | Issue: 3 | Pages: 454 - 459

Jun activation domain-binding protein 1 negatively regulate p27kip1 in non-Hodgkin’s lymphomas

Yuchan Wang, Min Fei, Chun Cheng, Dongmei Zhang, Jianxin Lu, Song He, Yueming Zhao, You Wang and Aiguo Shen
Volume: 7 | Issue: 3 | Pages: 460 - 467

Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells: The mechanisms involve ROS-mediated suppression of multidrug resistance and hypoxia inducible factor-1α

Xin-zhi Huang, Jie Wang, Chao Huang, Yu-ying Chen, Gui-ying Shi, Qing-shen Hu and Jing Yi
Volume: 7 | Issue: 3 | Pages: 468 - 475

Commentary

Chemosensitization by emodin, a plant-derived anti-cancer agent: mechanism of action

Yi Sun
Volume: 7 | Issue: 3 | Pages: 476 - 478

Erratum

Pre-clinical evaluation of 1-nitroacridine derived chemotherapeutic agent that has preferential cytotoxic activity towards prostate cancer

Kiranmayi Tadi, Badithe T. Ashok, Yuangen Chen, Debabrata Banerjee, Barbara Wysocka-Skrzela, Jerzy Konopa, Zbigniew Darzynkiewicz and Raj K. Tiwari
Volume: 7 | Issue: 3 | Page 479