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Table of Contents

June 2007

volume 6| issue 6



Editor's Corner

Cover Image


Volume: 6 | Issue: 6

Open Access Article



News

Could Micro-RNAs Act Downstream of p53 to Suppress Tumors?


Volume: 6 | Issue: 6 | Page 819

Open Access Article


Rosiglitazone, aka the Diabetes Drug Avandia, Improves Anti-Tumor Effect of Platinum-based Chemotherapy


Volume: 6 | Issue: 6 | Pages: 819 - 820

Open Access Article


Similarity in Patterns of Genomic Instability Point to Better Mouse Models of Human Tumors


Volume: 6 | Issue: 6 | Pages: 820 - 821

Open Access Article


Low Dose Dexamethasone Plus Lenalidomide Effective in Multiple Myeloma


Volume: 6 | Issue: 6 | Pages: 821 - 822

Open Access Article


Different Mutations Found in Melanoma Depending on When in Life Sun Exposure Occurred


Volume: 6 | Issue: 6 | Page 822

Open Access Article


FGFR2 Alterations Provide Therapeutic Target in Endometrial Cancer


Volume: 6 | Issue: 6 | Pages: 822 - 823

Open Access Article


Worldwide Scientific Community Presents Newest Findings of Collaborative Cancer Research


Volume: 6 | Issue: 6 | Pages: 823 - 824

Open Access Article


Srikumar Chellappan Named Moffitt Scientist of the Year 2007


Volume: 6 | Issue: 6 | Page 824

Open Access Article


Arizona and New Mexico Hold Historic Joint Cancer Summit


Volume: 6 | Issue: 6 | Pages: 824 - 826

Open Access Article


Congress of the International Society for Cellular Oncology: ISCO 2008 Amsterdam, the Netherlands, March 5-8, 2008


Volume: 6 | Issue: 6 | Page 826

Open Access Article


Myth: Sunscreen Is All You Need to Prevent Skin Cancer


Volume: 6 | Issue: 6 | Page 826

Open Access Article


More than $1 Million Granted for Patient-Centered Cancer Studies


Volume: 6 | Issue: 6 | Page 827

Open Access Article


Morphotek Signs Development and Clinical Supply Agreement with CMC Biopharmaceuticals A/S for Therapeutic Antibody to Treat Melanoma


Volume: 6 | Issue: 6 | Pages: 827 - 828

Open Access Article


Moffitt Receives $20.4 Million Gift from Philanthropist Donald A. Adam to Establish Comprehensive Melanoma Research Center


Volume: 6 | Issue: 6 | Page 828

Open Access Article


Canary Foundation and Stanford University Announce Center of Excellence for Cancer Early Detection


Volume: 6 | Issue: 6 | Pages: 828 - 829

Open Access Article


Penn Researchers Home In On Possible New Breast Cancer Gene


Volume: 6 | Issue: 6 | Pages: 829 - 830

Open Access Article


Researchers Discover Inherited Mutation for Leukemia


Volume: 6 | Issue: 6 | Pages: 830 - 831

Open Access Article



Review

Dysregulation of Stem Cell Signaling Network Due to Germline Mutation, SNP, Helicobacter Pylori Infection, Epigenetic Change, and Genetic Alteration in Gastric Cancer

Masaru Katoh
Volume: 6 | Issue: 6

Open Access Article



Clinical Trials

A Phase I Study of Thalidomide, Capecitabine and Temozolomide in Advanced Cancer

Damian A. Laber, M. Iltaf Khan, Goetz H. Kloecker, Cassandra Schonard, Beverly S. Taft and Carolina Salvador
Volume: 6 | Issue: 6

Open Access Article


Interim Analysis of Toxicity and Response in Phase 1 Trial of Systemic Targeted Alpha Therapy for Metastatic Melanoma

Chand Raja, Peter Graham, Syed Rizvi, Emma Song, Helen Goldsmith, John Thompson, Anja Bosserhoff, Alfred Morgenstern, Christos Apostolidis, John Kearsley, Ralph Reisfeld and Barry J Allen
Volume: 6 | Issue: 6

Open Access Article



Clinical Case Report

Bronchial Carcinoid Tumor Treated with Interferon and a New Vaccine Against NeuGcGM3 Antigen Expressed in Malignant Carcinoid Cells

Barroso Alvarez, Abraham Macías, Martinez G. Suarez, Molina L.E. Fernández and Dávila A Lage
Volume: 6 | Issue: 6

Open Access Article



Research Paper

The RUNX2 Transcription Factor Cooperates with the YES-associated Protein, YAP65, to Promote Cell Transformation

Michele I. Vitolo, Ian E. Anglin, William M. Mahoney, Jr., Keli J. Renoud, Ronald B. Gartenhaus, Kurtis E. Bachman and Antonino Passaniti
Volume: 6 | Issue: 6

Open Access Article


Reciprocal Regulation of 5α-dihydrotestosterone, Interleukin-6 and Interleukin-8 During Proliferation of Epithelial Ovarian Carcinoma

Yue Wang, Jie Yang, Yan Gao, Li Jie Dong, Shen Liu and Zhi Yao
Volume: 6 | Issue: 6

Open Access Article


Interferon-α Induces TRAIL Expression and Cell Death Via an IRF-1-Dependent Mechanism in Human Bladder Cancer Cells

Angela Papageorgiou, Colin P.N. Dinney and David J. McConkey
Volume: 6 | Issue: 6

Open Access Article


Gemcitabine Has Significant Immunomodulatory Activity in Murine Tumor Models Independent of its Cytotoxic Effects

Eiji Suzuki, Jing Sun, Veena Kapoor, Arminder S Jassar and Steven M. Albelda
Volume: 6 | Issue: 6

Open Access Article


Hela l-CaD Undergoes a DNA Replication-Associated Switch in Localization From the Cytoplasm to the Nuclei of Endothelial Cells/Endothelial Progenitor Cells in Human Tumor Vasculature

Ping-Pin Zheng, Marcel van der Weiden, Peter A.E. Sillevis Smitt, Theo M. Luider and Johan M. Kros
Volume: 6 | Issue: 6

Open Access Article


Contributing Factors of Temozolomide Resistance in MCF-7 Tumor Xenograft Models

Yoshinori Kato, Baasil Okollie, Venu Raman, Farhad Vesuna, Ming Zhao, Sharyn D. Baker, Zaver M. Bhujwalla and Dmitri Artemov
Volume: 6 | Issue: 6

Open Access Article


Pharmacokinetics and Toxicity of 213Bi-Labeled PAI2 in Preclinical Targeted Alpha Therapy for Cancer

Emma Y. Song, Syed M.A. Rizvi, Chang F Qu, Chand Raja, Martin W Brechbiel, Alfred Morgenstern, Christos Apostolidis and Barry J Allen
Volume: 6 | Issue: 6

Open Access Article


The Radiation-induced Cell-Death Signaling Pathway is Activated by Concurrent Use of Cisplatin in Sequential Biopsy Specimens from Patients with Cervical Cancer

Mayumi Iwakawa, Tatsuya Ohno, Kaori Imadome, Miyako Nakawatari, Ken-ichi Ishikawa, Minako Sakai, Shingo Katoh, Hitoshi Ishikawa, Hirohiko Tsujii and Takashi Imai
Volume: 6 | Issue: 6

Open Access Article


Imatinib and Nilotinib Induce Apoptosis of Chronic Myeloid Leukemia Cells Through a Bim-Dependant Pathway Modulated by Cytokines

Francis Belloc, François Moreau-Gaudry, Maialen Uhalde, Laurie Cazalis, Marie Jeanneteau, Francis Lacombe, Vincent Praloran and François-Xavier Mahon
Volume: 6 | Issue: 6

Open Access Article


Cationic Lipid Complexed Camptothecin (EndoTAG®-2) Improves Antitumoral Efficacy by Tumor Vascular Targeting

M.E. Eichhorn, S. Luedemann, S. Strieth, A. Papyan, H. Ruhstorfer, H. Haas, U. Michaelis, B. Sauer, M. Teifel, Gregory H. Enders, G. Brix, K.W. Jauch, C.J. Bruns and M. Dellian
Volume: 6 | Issue: 6

Open Access Article


The Expression Level of the Tumor Suppressor Retinoblastoma Protein (Rb) Influences the Antileukemic Efficacy of Erucylphospho-N,N,N-trimethylpropylammonium (ErPC3)

Deyan Y. Yosifov, Ilina K. Dineva, Maya M. Zaharieva, Spiro M. Konstantinov and Martin R. Berger
Volume: 6 | Issue: 6

Open Access Article


Targeted Inhibition of EG-1 Blocks Breast Tumor Growth

Ming Lu, Maryam R. Sartippour, Liping Zhang, Andrew J. Norris and Mai N. Brooks
Volume: 6 | Issue: 6

Open Access Article


Bridge Linkage Role Played by CD98hc of Anti-Tumor Drug Resistance and Cancer Metastasis on Cisplatin-Resistant Ovarian Cancer Cells

Hong Yang, Wei Zou, Yu Li, Biliang Chen and Xiaoyan Xin
Volume: 6 | Issue: 6

Open Access Article


Radiohybridization PET Imaging of KRAS G12D mRNA Expression in Human Pancreas Cancer Xenografts with [64Cu]DO3A-Peptide Nucleic Acid-Peptide Nanoparticles

A. Chakrabarti, K. Zhang, M. R. Aruva, A. W. Opitz, N. J. Wagner, M. L. Thakur and Eric Wickstrom
Volume: 6 | Issue: 6

Open Access Article


DDX39, Upregulated in Lung Squamous Cell Cancer, Displays RNA Helicase Activities and Promotes Cancer Cell Growth

Takeyuki Sugiura, Yuki Nagano and Yoshie Noguchi
Volume: 6 | Issue: 6

Open Access Article


P53 Dependent and Independent Apoptosis induced by Lidamycin in Human Colorectal Cancer Cells

Lihui Chen, Jianming Jiang, Chunlei Cheng, Ajing Yang, Qiyang He, Diandong Li and Zhen Wang
Volume: 6 | Issue: 6

Open Access Article


XIAP is Highly Expressed in Esophageal Cancer and its Downregulation by RNAi Sensitizes Esophageal Carcinoma Cell Lines to Chemotherapeutics

Shuguang Zhang, Fang Ding, Aiping Luo, Anguo Chen, Zaicheng Yu, Shuhua Ren, Zhihua Liu and Lin Zhang
Volume: 6 | Issue: 6

Open Access Article


In Vitro Efficacy of Immuno-Chemotherapy with Anti-EGFR Human Fab-Taxol Conjugate on A431 Epidermoid Carcinoma Cells

Xin Wang, Jin Zhu, Ping Zhao, Yongjun Jiao, Ning Xu, Tessa Grabinski, Chao Liu, Cindy K. Miranti, Tao Fu and Brian Cao
Volume: 6 | Issue: 6

Open Access Article



Profiles and Legacies

Think Big and Think Small

Michael B. Cohen
Volume: 6 | Issue: 6

Open Access Article