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Table of ContentsMay 2007volume 6| issue 5 |
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Editor's Corner
Cover Image
Volume: 6 | Issue: 5
Open Access Article
News
Imaging to Predict Therapeutic Response of Metastatic Disease to Bone
Volume: 6 | Issue: 5 | Page 629
Open Access Article
Proteasome Inhibitor NPI-0052 Appears More Effective than Bortezomib in Treatment of Leukemia in Animal Models
Volume: 6 | Issue: 5 | Pages: 629 - 630
Open Access Article
Proof-of-Principle That Targeting Telomerase Can Block Cancer Development Through Senescence Even if Cell Death is Blocked
Volume: 6 | Issue: 5 | Page 630
Open Access Article
Identifying Cancer Genetic Markers of Susceptibility Using High-Throughput SNP Arrays
Volume: 6 | Issue: 5 | Pages: 630 - 631
Open Access Article
MET Amplification and Resistance to EGFR-Targeted Small Molecule Therapies
Volume: 6 | Issue: 5 | Page 632
Open Access Article
Gene Signature in Simple Blood Test May Predict Dose of Radiation Exposure
Volume: 6 | Issue: 5 | Pages: 632 - 633
Open Access Article
EREG, COX2, MMP1 and MMP2 Orchestrate Breast Tumor Metastases
Volume: 6 | Issue: 5 | Page 633
Open Access Article
Pier Paolo Pandolfi Moves to Direct a new Cancer Genetics Program at Beth-Israel Deaconess Medical Center and Harvard Medical School
Volume: 6 | Issue: 5 | Page 634
Open Access Article
Steven Piantadosi to Direct Comprehensive Cancer Institute at Cedars-Sinai Medical Center
Volume: 6 | Issue: 5 | Pages: 634 - 635
Open Access Article
Matthew Seiden Named President and CEO of Fox Chase Cancer Center
Volume: 6 | Issue: 5 | Pages: 635 - 636
Open Access Article
Comprehensive Cancer Center at Stanford
Volume: 6 | Issue: 5 | Pages: 636 - 637
Open Access Article
Nicholas Petrelli Elected President of the Society of Surgical Oncology
Volume: 6 | Issue: 5 | Pages: 637 - 638
Open Access Article
Review
The Pathology of Tumor Stromatogenesis
Alexandra Giatromanolaki, Efthimios Sivridis and Michael I. KoukourakisVolume: 6 | Issue: 5 | Pages: 639 - 645
Journal Club
Selective Killing of Cancer Cells by a Cruciferous Vegetable Derived Pro-Oxidant Compound
Xin-jiang Wu and Xianxin HuaVolume: 6 | Issue: 5 | Pages: 646 - 647
Clinical Trials
A Phase I Clinical Trial of an Adenovirus-Mediated Endostatin Gene (E10A) in Patients with Solid Tumors
Xubin Lin, Huiqiang Huang, Su Li, Hongli Li, Yuhong Li, Ye Cao, Dongsheng Zhang, Yunfei Xia, Ying Guo, Wenlin Huang and Wenqi JiangVolume: 6 | Issue: 5 | Pages: 648 - 653
Open Access Article
Brief Communication
Gene-Specific Selection Against Experimental Fanconi Anemia Gene Inactivation in Human Cancer
Eike Gallmeier, Tomas Hucl, Eric S. Calhoun, Steven C. Cunningham, Fred Bunz, Jonathan R. Brody and Scott E. KernVolume: 6 | Issue: 5 | Pages: 654 - 660
Open Access Article
Allele-Dependent Variation in the Relative Cellular Potency of Distinct EGFR Inhibitors
Yuki Yuza, Karen A. Glatt, Jingrui Jiang, Heidi Greulich, Yuko Minami, Michele S. Woo, Takeshi Shimamura, Geoffrey Shapiro, Jeffrey C. Lee, Hongbin Ji, Whei Feng, Tzu-Hsiu Chen, Haruhiko Yanagisawa, Kwok-Kin Wong and Matthew MeyersonVolume: 6 | Issue: 5 | Pages: 661 - 667
Open Access Article
Research Paper
Expression Profiling Reveals Dysregulation of Cellular Cytoskeletal Genes in HBx–Induced Hepatocarcinogenesis
Qiang Sun, Youliang Wang, Yingai Zhang, Fang Liu, Xuan Cheng, Nin Hou, Xiaohang Zhao and Xiao YangVolume: 6 | Issue: 5 | Pages: 668 - 674
Open Access Article
Zebrafish tp53 Knockdown Extends the Survival of Irradiated Zebrafish Embryos More Effectively than the p53 Inhibitor Pifithrin
Kevin T. Duffy and Eric WickstromVolume: 6 | Issue: 5 | Pages: 675 - 678
Open Access Article
Comparative Evaluation of Survivin, Midkine, and CXCR4 Promoters for Transcriptional Targeting of Glioma Gene Therapy
Ilya V. Ulasov, Angel A. Rivera, Adam M. Sonabend, Adam M. Sonabend, Ming Wang, Zeng B. Zhu and Maciej S. LesniakVolume: 6 | Issue: 5 | Pages: 679 - 685
Open Access Article
Defibrotide: An Endothelium Protecting and Stabilizing Drug, has an Anti-Angiogenic Potential In vitro and In vivo
Gudrun E. Koehl, Edward K. Geissler, Massimo Iacobelli, Caroline Frei, Verena Burger, Silvia Haffner, Ernst Holler, Reinhard Andreesen, Hans J. Schlitt and Günther EissnerVolume: 6 | Issue: 5 | Pages: 686 - 690
Open Access Article
Caspase-8 Preferentially Senses the Apoptosis-Inducing Action of NG-18, A Gambogic Acid Derivative, in Human Leukemia HL-60 Cells
Zhijian Tao, Yunlong Zhou, Jinjian Lu, Wenhu Duan, Xinxia He, Liping Lin and Jian DingVolume: 6 | Issue: 5 | Pages: 691 - 696
Open Access Article
Phi29 pRNA Vector for Efficient Escort of Hammerhead Ribozyme Targeting Survivin in Multiple Cancer Cells
Hongyun Liu, Songchuan Guo, Richard Roll, Jie Li, Zhijuan Diao, Ningsheng Shao, Mark R. Riley, Alexander M. Cole, J. Paul Robinson, Nicholas Snead, Guanxin Shen and Peixuan GuoVolume: 6 | Issue: 5 | Pages: 697 - 704
Open Access Article
Induction of Endoplasmic Reticulum Stress by the Pro-Apoptotic Retinoid N-(4-Hydroxyphenyl)Retinamide Via a Reactive Oxygen Species-Dependent Mechanism in Human Head and Neck Cancer Cells
Humam Kadara, Ludovic Lacroix, Dafna Lotan and Reuben LotanVolume: 6 | Issue: 5 | Pages: 705 - 711
Open Access Article
Exploiting the TRIP-Br Family of Cell Cycle Regulatory Proteins as Chemotherapeutic Drug Targets in Human Cancer
Zhi Jiang Zang, Khe Guan Sim, Jit Kong Cheong, Christopher Maolin Yang, Chui Sun Yap and Stephen I-Hong HsuVolume: 6 | Issue: 5 | Pages: 712 - 718
Open Access Article
A New Putative Target for Antisense Gene Therapy of Glioma: Glycogen Synthase
Maryvonne Ardourel, Marion Blin, Jean-Luc Moret, Thierry Dufour, Huynh-Thien Duc, Tobias Hévor, Jerzy Trojan and Jean-François CloixVolume: 6 | Issue: 5 | Pages: 719 - 723
Open Access Article
Immune Analysis on mtHSV Mediated Tumor Therapy in HSV-1 Seropositive Mice
Huabin Zhu, Yue Su, Shumin Zhou, Wei Xiao, Weifang Ling, Baoli Hu, Yingle Liu and Yipeng QiVolume: 6 | Issue: 5 | Pages: 724 - 731
Open Access Article
Calcium/Calmodulin-Dependent Kinase II Plays an Important Role in Prostate Cancer Cell Survival
Oskar Rokhlin, Agshin F. Taghiyev, Ulrich K. Bayer, David Bumcrot, Victor E Kotelianski, Rebecca A. Glover and Michael B. CohenVolume: 6 | Issue: 5 | Pages: 732 - 742
Open Access Article
Axon Guidance Cue Netrin-1 has Dual Function in Angiogenesis
Yun Yang, Li Zou, Yong Wang, Ke-Shu Xu, Jin-Xiang Zhang and Jing-Hui ZhangVolume: 6 | Issue: 5 | Pages: 743 - 748
Open Access Article
Assessment of Apoptosis-Inducing Effects of Docetaxel Combined with the Proteasome Inhibitor PS-341 in Human Lung Cancer Cells
Cecilia S. Jung, Zhongmei Zhou, Fadlo R. Khuri and Shi-Yong SunVolume: 6 | Issue: 5 | Pages: 749 - 754
Open Access Article
AKT1, AKT2 and AKT3-Dependent Cell Survival is Cell Line-Specific and Knockdown of All Three Isoforms Selectively Induces Apoptosis in 20 Human Tumor Cell Lines
Sandra Koseoglu, Zhuomei Lu, Chandra Kumar, Paul Kirschmeier and Jun ZouVolume: 6 | Issue: 5 | Pages: 755 - 762
Open Access Article
Cancer Stem-Like Cells in Human Prostate Carcinoma Cells DU145: The Seeds of the Cell Line?
Wei Chen, Guomin Wang, Yujun Liu and Ruizhe QianVolume: 6 | Issue: 5 | Pages: 763 - 768
Open Access Article
Hypoxia Induced Overexpression of PrPC in Gastric Cancer Cell Lines
Jie Liang, Feihu Bai, Guanhong Luo, Jingbo Wang, Jingmei Liu, Fulin Ge, Yanglin Pan, Liping Yao, Rui Du, Xiaohua Li, Rui Fan, Hongbo Zhang, Xuegang Guo, Kaichun Wu and Daiming FanVolume: 6 | Issue: 5 | Pages: 769 - 774
Open Access Article
A Novel Polypeptide from Shark Cartilage with Potent Anti-Angiogenic Activity
Lanhong Zheng, Peixue Ling, Zheng Wang, Rongli Niu, Chaoxin Hu, Tianmin Zhang and Xiukun LinVolume: 6 | Issue: 5 | Pages: 775 - 780
Open Access Article
Immune Response to Firefly Luciferase as a Naked DNA
Yong Hyun Jeon, Yun Choi, Joo Hyun Kang, Chul Woo Kim, Jae Min Jeong, Dong Soo Lee and June-Key ChungVolume: 6 | Issue: 5 | Pages: 781 - 786
Open Access Article
BM6, a New Semi-Synthetic Vinca Alkaloid, Exhibits its Potent In Vivo Anti-Tumor Activities Via its High Binding Affinity for Tubulin and Improved Pharmacokinetic Profiles
Weihong Li, Yong Shao, Lihong Hu, Xiongwen Zhang, Yi Chen, Linjiang Tong, Chuan Li, Xu Shen and Jian DingVolume: 6 | Issue: 5 | Pages: 787 - 794
Open Access Article
Drug-Induced Inactivation or Gene Silencing of Class I Histone Deacetylases Suppresses Ovarian Cancer Cell Growth: Implications for Therapy
Dineo Khabele, Deok-Soo Son, Angelika K. Parl, Gary L. Goldberg, Leonard H. Augenlicht, John M. Mariadason and Valerie Montgomery RiceVolume: 6 | Issue: 5 | Pages: 795 - 801
Open Access Article
Commentary
Aiding and ABT’ing Treatment for Glioblastoma
Elaine Y. Chung, Michael Dews, Amit Maity and Andrei Thomas-TikhonenkoVolume: 6 | Issue: 5 | Pages: 802 - 804
Open Access Article
Profiles and Legacies
Pursuing the Androgen Pathway on the Quest to Control Prostate Cancer
Donald J. TindallVolume: 6 | Issue: 5 | Pages: 805 - 810
Open Access Article
The Accidental Cancer Geneticist: Hilário de Gouvêa and Hereditary Retinoblastoma
Alvaro N.A. Monteiro and Ricardo WaizbortVolume: 6 | Issue: 5 | Pages: 811 - 813