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Table of Contents

November 2007

volume 6| issue 11



News


Volume: 6 | Issue: 11

Editor's Corner

Cover Image


Volume: 6 | Issue: 11

News

Mutant zebrafish identify role for birc2 in healthy angiogenesis


Volume: 6 | Issue: 11 | Page 1665

Genes that both extend life and protect against cancer identified


Volume: 6 | Issue: 11 | Pages: 1665 - 1666

"Network" approach yields discovery of a potential breast cancer susceptibility gene


Volume: 6 | Issue: 11 | Pages: 1666 - 1667

Gastric progenitor cells divide in response to inflammation


Volume: 6 | Issue: 11 | Pages: 1667 - 1668

Standard treatment for prostate cancer may encourage spread of disease: finding may lead to changes in androgen deprivation therapy


Volume: 6 | Issue: 11 | Pages: 1668 - 1669

Genome update defines landscape of breast and colon cancer: represents next major step in cancer genome sequencing


Volume: 6 | Issue: 11 | Pages: 1669 - 1670

Broccoli sprout-derived extract protects against ultraviolet radiation


Volume: 6 | Issue: 11 | Page 1670

Sidestepping cancer's chaperone: UMass Medical School scientists target the mitochondria of tumor cells with novel anticancer agents


Volume: 6 | Issue: 11 | Pages: 1670 - 1671

Identification of new genes shows a complex path to cancer: UMass Medical School investigators define multi-step pathway that allows for cancer cell development and growth


Volume: 6 | Issue: 11 | Page 1671

Survival data in FDA approval for ERBITUX® (CETUXIMAB) supports use as a single agent in patients with advanced colorectal cancer


Volume: 6 | Issue: 11 | Pages: 1671 - 1673

An AIDS-related virus reveals more ways to cause cancer, Penn researchers find


Volume: 6 | Issue: 11 | Page 1673

Drug combination might offer hope for patients with deadly brain tumors


Volume: 6 | Issue: 11 | Pages: 1673 - 1674

Scientists identify new gene associated with lung cancer


Volume: 6 | Issue: 11 | Page 1674

Cancer researcher received prestigious national award for her significant contributions to cancer research: American Cancer Society's Distinguished Service Award given to UCLA's Dr. Patricia Ganz


Volume: 6 | Issue: 11 | Pages: 1674 - 1675

Review

CARPs are E3 Ligases that Target Apical Caspases and p53

Wensheng Yang and Wafik S. El-Deiry
Volume: 6 | Issue: 11 | Pages: 1676 - 1683

Cancer Stem Cell and Cancer Stemloids: From Biology to Therapy

Mikhail V. Blagosklonny
Volume: 6 | Issue: 11 | Pages: 1684 - 1689

Clinical Trials

Phase II Trial of Single Agent Val-boroPro (Talabostat) Inhibiting Fibroblast Activation Protein in Patients with Metastatic Colorectal Cancer

Kalyani Narra, Stefanie R. Mullins, Hyung-Ok Lee, Brenda Strzemkowski-Brun, Kimberly Magalong, Victoria J. Christiansen, Patrick A. McKee, Brian Egleston, Steven J. Cohen, Louis M. Weiner, Neal J. Meropol and Jonathan D. Cheng
Volume: 6 | Issue: 11 | Pages: 1691 - 1699

Bedside to Bench

Nephron-Sparing Surgery of a Low Grade Renal Cell Carcinoma in a Renal Allograft 12 Years after Transplantation

Thomas M. Mundel, Karl-Ludwig Schaefer, Mario Colombo-Benkmann, Karl-Heinz Dietl, Raihana Diallo-Danebrock and Norbert Senninger
Volume: 6 | Issue: 11 | Pages: 1700 - 1703

Research Paper

Functional Expression of TLR9 is Associated to the Metastatic Potential of Human Lung Cancer Cell

Tao Ren, Zhen-Ke Wen, Zhong-Min Liu, Yong-Jie Liang, Zhong-Liang Guo and Lin Xu
Volume: 6 | Issue: 11 | Pages: 1704 - 1709

Methylation-Induced Silencing of ASC/TMS1, a Pro-Apoptotic Gene, is a Late-Stage Event in Colorectal Cancer

Marco A. Riojas, Mingzhou Guo, Sabine C. Glöckner, Emi Ota Machida, Stephen B. Baylin and Nita Ahuja
Volume: 6 | Issue: 11 | Pages: 1710 - 1716

Magnetic Resonance Imaging for Detection and Determination of Tumor Volume in a Genetically Engineered Mouse Model of Ovarian Cancer

Harvey Hensley, Bridget A. Quinn, Ronald L. Wolf, Samuel L. Litwin, Seiji Mabuchi, Stephen J. Williams, Christine Williams, Thomas C. Hamilton and Denise C. Connolly
Volume: 6 | Issue: 11 | Pages: 1717 - 1725

The Oncolytic Adenovirus Targeting to TERT and RB Pathway Induced Specific and Potent Anti-Tumor Efficacy In Vitro and In Vivo for Hepatocellular Carcinoma

Wei Zhang, Rong Cai, Jingjing Luo, Yingxin Wang, Qiang Cui, Xubin Wei, Hongfeng Zhang and Cheng Qian
Volume: 6 | Issue: 11 | Pages: 1726 - 1732

Regulation of the CLDN3 Gene in Ovarian Cancer Cells

Hiroshi Honda, Michael J. Pazin, Theresa D'Souza, Hongxiu Ji and Patrice J. Morin
Volume: 6 | Issue: 11 | Pages: 1733 - 1742

Pentoxifylline Modulates Cell Surface Integrin Expression and Integrin Mediated Adhesion of B16F10 Cells to Extracellular Matrix Components

Aparna Ratheesh, Arvind Ingle and Rajiv P. Gude
Volume: 6 | Issue: 11 | Pages: 1743 - 1752

Serial Endoscopy in Azoxymethane Treated Mice Using Ultra-High Resolution Optical Coherence Tomography

Lida P. Hariri, Ziping Qiu, Alexandre R. Tumlinson, David G. Besselsen, Eugene W. Gerner, Natalia Ignatenko, Boris Povazay, Boris Hermann, Harald Sattmann, James McNally, Angelika Unterhuber, Wolfgang Drexler and Jennifer K. Barton
Volume: 6 | Issue: 11 | Pages: 1753 - 1762

PDGFRβ and HIF-1α Inhibition with Imatinib and Radioimmunotherapy of Experimental Prostate Cancer

Yu Kimura, Kotaro Inoue, Michio Abe, Jessica Nearman and Janina Baranowska-Kortylewicz
Volume: 6 | Issue: 11 | Pages: 1763 - 1772

Redirecting Adaptive Immunity Against Foreign Antigens to Tumors for Cancer Therapy

Wenxian Hu, John J. Davis, Hongbo Zhu, Fengqin Dong, Wei Guo, Jian Ang, Henry Peng, Z. Sheng Guo, David L. Bartlett, Stephen G. Swisher and Bingliang Fang
Volume: 6 | Issue: 11 | Pages: 1773 - 1781

Chemoradiation-Induced Expression of Fibroblast Growth Factor-2 and Laminin in Patients with Cervical Cancer

Miyako Nakawatari, Mayumi Iwakawa, Tatsuya Ohno, Shingo Katoh, Tomoaki Tamaki, Kaori Imadome, Minako Sakai, Hirohiko Tsujii and Takashi Imai
Volume: 6 | Issue: 11 | Pages: 1780 - 1786

A Cyclic Chimeric Interferon-α2b Peptide Induces Apoptosis in Tumor Cells

Viviana C. Blank, Clara Peña and Leonor P. Roguin
Volume: 6 | Issue: 11 | Pages: 1787 - 1793

Reactive Oxygen Species Contribute to Cell Killing and P-glycoprotein Downregulation by Salvicine in Multidrug Resistant K562/A02 Cells

Yujun Cai, Jinjian Lu, Zehong Miao, Liping Lin and Jian Ding
Volume: 6 | Issue: 11 | Pages: 1794 - 1799

Possible Roles of Vinexinβ in Growth and Paclitaxel Sensitivity in Human Prostate Cancer PC-3 Cells

Kosuke Mizutani, Koh-ichi Nagata, Hidenori Ito, Hidetoshi Ehara, Yoshinori Nozawa and Takashi Deguchi
Volume: 6 | Issue: 11 | Pages: 1800 - 1804

Serological Identification and Bioinformatics Analysis of Immunogenic Antigens in Osteosarcoma

Bo Liao, Baoan Ma, Zhe Liu, Huizhong Zhang, Hua Long, Tongtao Yang and Qingyu Fan
Volume: 6 | Issue: 11 | Pages: 1805 - 1809

Effect of Dietary Tetradecylthioacetic Acid on Colon Cancer Growth Studied by Dynamic Contrast Enhanced MRI

Line R. Jensen, Kjetil Berge, Tone F. Bathen, Hege Wergedahl, Svanhild A. Schønberg, Anna Bofin, Rolf K. Berge and Ingrid S. Gribbestad
Volume: 6 | Issue: 11 | Pages: 1810 - 1816

Profiles and Legacies

Gene Expression in Nuclear Microenvironments for Biological Control and Cancer

Gary S. Stein
Volume: 6 | Issue: 11 | Pages: 1817 - 1821