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Table of Contents

January 2007

volume 6| issue 1



Editor's Corner

Cover Image


Volume: 6 | Issue: 1

Open Access Article


Cancer Biology & Therapy Celebrates Five Years of Publication

Wafik S. El-Deiry
Volume: 6 | Issue: 1 | Pages: 3 - 4

Open Access Article



News

Bortezomib and Lenalidomide effective in Myeloma


Volume: 6 | Issue: 1

Open Access Article


Beneficial Effects of Estrogen in Colon Cancer


Volume: 6 | Issue: 1

Open Access Article


Maternal Diet and Risk of Cancer in Offspring


Volume: 6 | Issue: 1

Open Access Article


Targeting Glioblastoma Stem Cells with BMP4


Volume: 6 | Issue: 1

Open Access Article


Levels of NAC-1 May Predict Recurrence of Ovarian Cancer


Volume: 6 | Issue: 1

Open Access Article


iHOP, A New Gene and Protein Analysis Tool


Volume: 6 | Issue: 1

Open Access Article


Lapatinib Shows Promise for Inflammatory Breast Cancer


Volume: 6 | Issue: 1

Open Access Article


Cromolyn, an Allergy Drug, Inhibits Pancreatic Cancer in Animal Models


Volume: 6 | Issue: 1

Open Access Article


Bortezomib Plus Doxorubicin Combination Slows Progression of Multiple Myeloma


Volume: 6 | Issue: 1

Open Access Article


T-Regulatory Cells Predict Recurrence in Lung Cancer Patients


Volume: 6 | Issue: 1

Open Access Article



Review

Colorectal Cancer: New Advances in Immunotherapy

Rafael Cubas, Min Li, Changyi Chen and Qizhi Yao
Volume: 6 | Issue: 1 | Pages: 11 - 17

Open Access Article



Clinical Case Report

Evidence of Myeloid Differentiation in non-M3 Acute Myeloid Leukemia Treated with the Retinoid X Receptor Agonist Bexarotene

Donald E. Tsai, Selina Luger, Allison Kemner, Cezary Swider, Ami Goradia, Ewa Tomczak, Doris DiPatri, Adam Bagg, Peter Nowell, Alison W. Loren, Alexander Perl, Stephen Schuster, James E. Thompson, David Porter, Charlambos Andreadis, Edward A. Stadtmauer, Steven Goldstein, Richard Ghalie and Martin Carroll
Volume: 6 | Issue: 1 | Pages: 18 - 21

Open Access Article



Clinical Trials

Diagnostic Efficacy and Safety of 99mTc-Labeled Monoclonal Antibody ior c5 in Patients with Colorectal and Anal Carcinomas: Final Report Clinical Trial Phase I/II

Mayra Ramos-Suzarte, Alejandro Perera Pintado, Nelson M. Rodríguez, Juan P. Oliva, Normando Iznaga-Escobar, Leonel T. Aroche, Gilmara Pimentel, Joaquín González, Maria Cordero, Obaya T. Rodríguez, Ramos T. Crombet and Rodríguez R. Perez
Volume: 6 | Issue: 1 | Pages: 22 - 29

Open Access Article



Research Paper

Differential Activity of Sulindac Metabolites Against Squamous Cell Carcinoma of the Head and Neck is Mediated by p21waf1/cip1 Induction and Cell Cycle Inhibition

Jonathan M Bock, Sarita G Menon, Prabhat C Goswami, Lori L Sinclair, Nichole S Bedford, Robert E Jackson and Douglas K Trask
Volume: 6 | Issue: 1 | Pages: 30 - 39

Open Access Article


Expression of TMPRSS2:ERG Gene Fusion in Prostate Cancer Cells is an Important Prognostic Factor for Cancer Progression

Robert K Nam, Linda Sugar, Zhenghui Wang, Wenyi Yang, Richard Kitching, Laurence H Klotz, Vasundara Venkateswaran, Steven A Narod and Arun Seth
Volume: 6 | Issue: 1 | Pages: 40 - 45

Open Access Article



Commentary

TMPRSS2:ERG Gene Fusion: A New Genetic Marker for Prostate Cancer Progression

Marcella Macaluso and Antonio Giordano
Volume: 6 | Issue: 1 | Pages: 46 - 47

Open Access Article



Research Paper

In Vitro Comparison of the Vitamin D Endocrine System in 1,25(OH)2D3-Responsive and –Resistant Melanoma Cells

Jörg Reichrath, Martin Rech, Maryam Moeini, Eckart Meese, Wolfgang Tilgen and Markus Seifert
Volume: 6 | Issue: 1 | Pages: 48 - 55

Open Access Article


Quercetin, Siamois 1 and Siamois 2 Induce Apoptosis in Human Breast Cancer MDA-MB-435 Cells Xenograft In Vivo

Samarn Dechsupa, Suchart Kothan, Jackie Vergote, Gerard Leger, Antoine Martineau, Simone Beranger, Rachian Kosanlavit, Jean-Luc Moretti and Samlee Mankhetkorn
Volume: 6 | Issue: 1 | Pages: 56 - 61

Open Access Article



Commentary

Polyphenols in Breast Cancer Treatment

Richard A. Franklin and James McCubrey
Volume: 6 | Issue: 1 | Pages: 62 - 63

Open Access Article



Research Paper

Histone Deacetylase Inhibitor LBH589 Reactivates Silenced Estrogen Receptor Alpha (ER) Gene Expression without Loss of DNA Hypermethylation

Qun Zhou, Peter Atadja and Nancy E. Davidson
Volume: 6 | Issue: 1 | Pages: 64 - 69

Open Access Article


Detecting Changes in Tumor Hypoxia with Carbonic Anhydrase IX and Pimonidazole

Kyung Hwan Shin, Juan A Diaz-Gonzalez, James Russell, Qing Chen, Paul Burgman, Xiao-Feng Li and C. Cliffton Ling
Volume: 6 | Issue: 1 | Pages: 70 - 75

Open Access Article


Profile of Ets Gene Expression in Human Breast Carcinoma

Jin He, Yong Pan, Jianhua Hu, Constance Albarracin, Yun Wu and Jia Le Dai
Volume: 6 | Issue: 1 | Pages: 76 - 82

Open Access Article



Commentary

ETS Genes in Breast Cancer: A Step in the Right Direction

Xinyan Wu and Saraswati Sukumar
Volume: 6 | Issue: 1 | Pages: 83 - 84

Open Access Article



Research Paper

Growth Inhibitory Effects of Gastric Cancer Cells with an Increase in S Phase and Alkaline Phosphatase Activity Repression by Aloe-emodin

Junming Guo, Bingxiu Xiao, Shun Zhang, Donghai Liu, Yiping Liao and Qian Sun
Volume: 6 | Issue: 1 | Pages: 85 - 88

Open Access Article



Commentary

Aloe(-emodin) for Cancer? More than Just a Comforting Salve

Jay F. Dorsey and Gary D. Kao
Volume: 6 | Issue: 1 | Pages: 89 - 90

Open Access Article



Research Paper

Slow Acetylator Genotype of N-Acetyl Transferase2 (NAT2) is Associated with Increased Susceptibility to Gallbladder Cancer; The Cancer Risk Not Modulated by Gallstone Disease

Sachchida N. Pandey, Balraj Mittal, Gourdas Choudhuri and Dinesh R. Modi
Volume: 6 | Issue: 1 | Pages: 91 - 96

Open Access Article



Commentary

Predisposed to Toxins: Association of Gallbladder Cancer with N-Acetyl Transferase SNPs

Justin L. Mott and Gregory J. Gores
Volume: 6 | Issue: 1 | Pages: 97 - 98

Open Access Article



Research Paper

PPARγ Ligands Enhance TRAIL-induced Apoptosis through DR5 Upregulation and c-FLIP Downregulation in Human Lung Cancer Cells

Wei Zou, Xiangguo Liu, Ping Yue, Fadlo R. Khuri and Shi-Yong Sun
Volume: 6 | Issue: 1 | Pages: 99 - 106

Open Access Article



Commentary

PPARγ Agonists Follow an Unknown TRAIL in Lung Cancer

Stanley Lipkowitz and Phillip A. Dennis
Volume: 6 | Issue: 1 | Pages: 107 - 109

Open Access Article


"D" Approach to Prevent Metastasis

Lucia R. Languino and Vivek Rangnekar
Volume: 6 | Issue: 1 | Pages: 110 - 111

Open Access Article


Predicting Response to EGFR-Tyrosine Kinase Inhibitors Among Diverse Ancestries: Just 'Way Too Polymorphic

Kevin M. Zbuk and Charis Eng
Volume: 6 | Issue: 1 | Pages: 112 - 115

Open Access Article


The p53 Family: Prospect for Cancer Gene Therapy

Jin Zhang and Xinbin Chen
Volume: 6 | Issue: 1 | Pages: 116 - 118

Open Access Article


Is ERK Activation a Good Biomarker for Estradiol and Tamoxifen Effects?

Keiran S.M. Smalley and Keith T. Flaherty
Volume: 6 | Issue: 1 | Pages: 119 - 120

Open Access Article


Targeting PECAM-1 for Anti-Cancer Therapy

Horace M. DeLisser
Volume: 6 | Issue: 1 | Pages: 121 - 122

Open Access Article


Reg IV Can Serve for Early Diagnosis and Therapy

Irene Pankova-Kholmyansky and Nadir Arber
Volume: 6 | Issue: 1 | Pages: 123 - 124

Open Access Article


The Role of CD44 in HNSCC

Aaron D. Nelson and Jennifer Grandis
Volume: 6 | Issue: 1 | Pages: 125 - 126

Open Access Article