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Table of Contents

september 2006

volume 5| issue 9



Editor's Corner

Cover Image


Volume: 5 | Issue: 9

Open Access Article



News

Celecoxib Reduces Size and Occurrence of Adenomas


Volume: 5 | Issue: 9 | Page 1051

Open Access Article


A Prolyl Hydroxylase Contributes to Anti-Angiogenic Effect of p53


Volume: 5 | Issue: 9 | Page 1051

Open Access Article


Chromosome 8q24 Linked to Elevated Prostate Cancer Risk in African Americans


Volume: 5 | Issue: 9 | Page 1052

Open Access Article


MC1R Variants May Contribute to Melanoma Risk


Volume: 5 | Issue: 9 | Page 1052

Open Access Article


Notch2 and CDK5 as Therapeutic Targets


Volume: 5 | Issue: 9 | Page 1053

Open Access Article


CALM-AF10 Fusion Gives Clues to Disregulated HoxA5 and Leukemia Development


Volume: 5 | Issue: 9 | Page 1054

Open Access Article


Genomic Profiling of Lung Cancer Predicts Recurrence Suggesting Which Patients May in the Future Benefit From Aggressive Treatment


Volume: 5 | Issue: 9 | Page 1054

Open Access Article


Cyclin D1 Connections to the Mitochondria


Volume: 5 | Issue: 9 | Page 1055

Open Access Article


BRCA1 and BRCA2 Mutations and Cancer Risk in African American and Caucasian Women


Volume: 5 | Issue: 9 | Page 1056

Open Access Article


Burnham Expands to Sunshine State


Volume: 5 | Issue: 9 | Page 1057

Open Access Article



Review

Cross-Talk of WNT and FGF Signaling Pathways at GSK3ß to Regulate ß-Catenin and SNAIL Signaling Cascades

Masuko Katoh and Masaru Katoh
Volume: 5 | Issue: 9 | Pages: 1059 - 1064

Open Access Article


Therapeutic Targets: MTOR and Related Pathways

Janet E. Dancey
Volume: 5 | Issue: 9 | Pages: 1065 - 1073

Open Access Article



Focused Review Series

Treatment Strategies for Skeletal Complications of Cancer

James Berenson, Lakshmi Rajdev and Michael Broder
Volume: 5 | Issue: 9 | Pages: 1074 - 1077

Open Access Article


Pathophysiology of Bone Metastases

James Berenson, Lakshmi Rajdev and Michael Broder
Volume: 5 | Issue: 9 | Pages: 1078 - 1081

Open Access Article


Bone Complications in Multiple Myeloma

James Berenson, Lakshmi Rajdev and Michael Broder
Volume: 5 | Issue: 9 | Pages: 1082 - 1085

Open Access Article


Managing Bone Complications of Solid Tumors

James Berenson, Lakshmi Rajdev and Michael Broder
Volume: 5 | Issue: 9 | Pages: 1086 - 1089

Open Access Article



Journal Club

The Limitless Role of p53 in Cell Cycle Machinery: Good News or Bad News?

Paraskevi Vogiatzi, Marco Cassone, Giovanni Abbadessa and Pier Paolo Claudio
Volume: 5 | Issue: 9 | Pages: 1090 - 1093

Open Access Article


The Quantification of PSA mRNA Copies in Pathologically Normal Pelvic Lymph Nodes is a Viable Prognostic Indicator

Jacob N. Beverage and William D. Figg
Volume: 5 | Issue: 9 | Pages: 1094 - 1095

Open Access Article


Taming NEMO to Slay Cancer Cells

Kimberly A. Scata and Wafik S. El-Deiry
Volume: 5 | Issue: 9 | Pages: 1096 - 1097

Open Access Article



Clinical Study

Childhood Cancer in Families with and without BRCA1 or BRCA2 Mutations Ascertained at a High-Risk Breast Cancer Clinic

Gabriel A. Brooks, Jill E. Stopfer, Julie Erlichman, Rebecca Davidson, Katherine L. Nathanson and Susan M. Domchek
Volume: 5 | Issue: 9 | Pages: 1098 - 1102

Open Access Article



Commentary

BRCA Mutations and Childhood Cancer

Roger Greenberg
Volume: 5 | Issue: 9 | Pages: 1103 - 1104

Open Access Article



Clinical Study

Hepatic Transport, Metabolism and Biliary Excretion of Irinotecan in a Cancer Patient with an External Bile Drain

Floris A. de Jong, Jos J.E.M Kitzen, Peter de Bruijn, Jaap Verweij and Walter J. Loos
Volume: 5 | Issue: 9 | Pages: 1105 - 1110

Open Access Article



Research Paper

Pheophorbide a, An Active Compound Isolated from Scutellaria barbata, Possesses Photodynamic Activities by Inducing Apoptosis in Human Hepatocellular Carcinoma

Patrick Ming-Kuen Tang, Judy Yuet-Wa Chan, Shannon Wing-Ngor Au, Siu-Kai Kong, Stephen Kwok-Wing Tsui, Mary Mui-Yee Waye, Thomas Chung-Wai Mak, Wing-Ping Fong and Kwok-Pui Fung
Volume: 5 | Issue: 9 | Pages: 1111 - 1116

Open Access Article



Commentary

Enhancing the Efficacy of Photodynamic Therapy by a Chinese Herbal Medicine for Hepatocellular Carcinoma

Juan Ma, Minhu Chen, Yun Dai and Liang Qiao
Volume: 5 | Issue: 9 | Pages: 1117 - 1119

Open Access Article



Research Paper

Development of a Flexible and Potent Hypoxia-Inducible Promoter for Tumor-Targeted Gene Expression in Attenuated Salmonella

Asferd Mengesha, Ludwig Dubois, Philippe Lambin, Willy Landuyt, Roland K. Chiu, Bradly G. Wouters and Jan Theys
Volume: 5 | Issue: 9 | Pages: 1120 - 1128

Open Access Article


The Biochemical Changes Associated with Phytic Acid on Induced Breast Proliferative Lesions In Rats: Preliminary Findings

Mahmoud R. Hussein, Mohamad A Abd EL-Aziz, Nagwa S Ahmad, Faten Omran and Mohamad Abdulhameed
Volume: 5 | Issue: 9 | Pages: 1129 - 1133

Open Access Article



Commentary

Phytic Acid: A Phytochemical with Complementary and Alternative Benefits

Suzanne Bakewell
Volume: 5 | Issue: 9 | Pages: 1134 - 1135

Open Access Article



Research Paper

The BRK Tyrosine Kinase is Expressed in High-Grade Serous Carcinoma of the Ovary

Rosemarie E. Schmandt, Marsha Bennett, Stephanie Clifford, Angela Thornton, Feng Jiang, Russell R. Broaddus, Charlotte C. Sun, Karen H. Lu, Anil K. Sood and David Gershenson
Volume: 5 | Issue: 9 | Pages: 1136 - 1141

Open Access Article


Differential Mechanisms of Radiosensitization by 2-deoxy-D-glucose in the Monolayers and Multicellular Spheroids of a Human Glioma Cell Line

Divya Khaitan, Sudhir Chandna, M.B. Arya and B.S. Dwarakanath
Volume: 5 | Issue: 9 | Pages: 1142 - 1151

Open Access Article



Commentary

The Radiosensitization Effect of 2-Deoxy-D-Glucose on Human Glioma Cells

Rohini Gomathinayagam and Chendil Damodaran
Volume: 5 | Issue: 9 | Pages: 1152 - 1153

Open Access Article



Research Paper

Reversal of p53 Epigenetic Silencing in Multiple Myeloma Permits Apoptosis by a p53 Activator

Elaine M. Hurt, Suneetha B. Thomas, Benjamin Peng and William L. Farrar
Volume: 5 | Issue: 9 | Pages: 1154 - 1160

Open Access Article



Commentary

Reactivation of p53 Function with a Demethylating Agent: Awakening a Sleeping Giant

Paul G. Corn
Volume: 5 | Issue: 9 | Pages: 1161 - 1162

Open Access Article



Research Paper

Characterization of CD44v3 Containing Isoforms in Head and Neck Cancer

Erika P. Reategui, Adriana Antúnez de Mayolo, Parpha M. Das, Frank C. Astor, Rakesh Singal, Kara L. Hamilton, W. Jarrard Goodwin, Kermit L. Carraway and Elizabeth J. Franzmann
Volume: 5 | Issue: 9 | Pages: 1163 - 1168

Open Access Article


Extracellular Pressure Stimulates Tumor Cell Adhesion In Vitro by Paxillin Activation

J. van der Voort van Zyp, W.C. Conway, D.H. Craig, N. van der Voort van Zyp, V. Thamilselvan and M.D. Basson
Volume: 5 | Issue: 9 | Pages: 1169 - 1178

Open Access Article


Agonistic Monoclonal Antibodies Potentiate Tumorigenic and Invasive Activities of Splicing Variant of the RON Receptor Tyrosine Kinase

Hang-Ping Yao, Yu-Lan Luo, Lei Feng, Lin-Fang Cheng, Yi Lu, Wei Li and Ming-Hai Wang
Volume: 5 | Issue: 9 | Pages: 1179 - 1186

Open Access Article



Commentary

New Tools for Dissecting RON Receptor Tyrosine Kinase Oncogenic Signaling

Joseph L. Kissil and Alan Charest
Volume: 5 | Issue: 9 | Pages: 1187 - 1188

Open Access Article



Research Paper

A Non-Invasive Method for Detection of Intestinal Mucositis Induced by Different Classes of Chemotherapy Drugs in the Rat

Gordon S. Howarth, Katie L Tooley, Geoffrey P. Davidson and Ross N. Butler
Volume: 5 | Issue: 9 | Pages: 1189 - 1195

Open Access Article



Commentary

Sucrose Breath Testing and Intestinal Mucositis

Dorothy M. Keefe and Rachel J. Gibson
Volume: 5 | Issue: 9 | Pages: 1196 - 1198

Open Access Article



Research Paper

TSA-Induced Cell Death in Prostate Cancer Cell Lines is Caspase-2 Dependent and Involves the PIDDosome

Agshin F. Taghiyev, Natalya V. Guseva, Rebecca A. Glover, Oskar W. Rokhlin and Michael B. Cohen
Volume: 5 | Issue: 9 | Pages: 1199 - 1205

Open Access Article


Radiosensitizing Effects of the Prenyltransferase Inhibitor AZD3409 Against RAS Mutated Cell Lines.

Keith A. Cengel, Erik Deutsch, Trevor C. Stephens, K. Ranh Voong, Gary D. Kao and Eric J. Bernhard
Volume: 5 | Issue: 9 | Pages: 1206 - 1210

Open Access Article


Verotoxin-1 Induction of Apoptosis in Gb3-expressing Human Glioma Cell Lines

David Johansson, Anders Johansson, Kjell Grankvist, Ulrika Andersson, Roger Henriksson, Per Bergström, Thomas Brännström and Parviz Behnam-Motlagh
Volume: 5 | Issue: 9 | Pages: 1211 - 1217

Open Access Article


Expression of Cancer-Testis Antigens as Possible Targets for Antigen-Specific Immunotherapy in Head and Neck Squamous Cell Carcinoma

Djordje Atanackovic, Inga Blum, Yanran Cao, Sören Wenzel, Katrin Bartels, Christiane Faltz, Dieter Kurt Hossfeld, Susanna Hegewisch-Becker, Carsten Bokemeyer, Rudolf Leuwer
Volume: 5 | Issue: 9 | Pages: 1218 - 1225

Open Access Article



Commentary

Cancer-Testis Antigens in Tumor Biology and Immunotherapy

Carolyn Clark and Robert Vonderheide
Volume: 5 | Issue: 9 | Pages: 1226 - 1227

Open Access Article



Research Paper

Identification and Characterization of Proteins Interacting with Traf4, an Enigmatic p53 Target

Laura M. Rozan and Wafik S. El-Deiry
Volume: 5 | Issue: 9 | Pages: 1228 - 1235

Open Access Article



Commentary

The Problem of Platinum Resistance

Barbara G. Campling
Volume: 5 | Issue: 9 | Pages: 1236 - 1237

Open Access Article


Thymidylate Synthase as a Chemotherapeutic Drug Target: Where Are We after Fifty Years?

Franklin G. Berger and Sondra H. Berger
Volume: 5 | Issue: 9 | Pages: 1238 - 1241

Open Access Article


Long Term Responses with Cetuximab Therapy in Glioblastoma Multiforme

Robert Lustig
Volume: 5 | Issue: 9 | Pages: 1242 - 1243

Open Access Article



Profiles and Legacies

Stem Cells, Differentiation, and Cancer: Mentors, Colleagues and Academic Administration

Lorraine J. Gudas
Volume: 5 | Issue: 9 | Pages: 1244 - 1246

Open Access Article