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Table of Contents

august 2006

volume 5| issue 8



Editor's Corner

Cover Image

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Volume: 5 | Issue: 8

Open Access Article


Robert B. Dickson

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Volume: 5 | Issue: 8 | Pages: 895 - 896

Open Access Article



News

Differences Between Normal and Leukemia Stem Cells

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Volume: 5 | Issue: 8 | Pages: 897 - 900

Open Access Article


Stress and the Spread of Ovarian Cancer in Mice

N/A
Volume: 5 | Issue: 8 | Pages: 897 - 900

Open Access Article


Acetyl CoA Production Provides Link between Sugar Metabolism and Gene Expression

N/A
Volume: 5 | Issue: 8 | Pages: 897 - 900

Open Access Article


Targeting ALDH to Block Hematopoietic Stem Cell Differentiation

N/A
Volume: 5 | Issue: 8 | Pages: 897 - 900

Open Access Article



Review

Stem Cells in Prostate Cancer: Resolving the Castrate-Resistant Conundrum and Implications for Hormonal Therapy

Nima Sharifi, Brian T. Kawasaki, Elaine M. Hurt and William L. Farrar
Volume: 5 | Issue: 8 | Pages: 901 - 906

Open Access Article



Journal Club

Ubiquitination of Myc: Flipping the Switch

Amelie Boquoi and Gregory Enders
Volume: 5 | Issue: 8 | Pages: 907 - 908

Open Access Article


Lysyl Oxidase (LOX) and Hypoxia-Induced Metastases

Amy M. Sion and William D. Figg
Volume: 5 | Issue: 8 | Pages: 909 - 911

Open Access Article



Clinical Case Report

Long Term Responses with Cetuximab Therapy in Glioblastoma Multiforme

Cristóbal Belda-Iniesta, Javier de Castro Carpeño, Enrique Casado Saenz, Manuel Gutiérrez, Rosario Perona and Manuel González Barón
Volume: 5 | Issue: 8 | Pages: 912 - 914

Open Access Article



Brief Communication

Dexamethasone Protects Against Cisplatin-Induced Activation of the Mitochondrial Apoptotic Pathway in Human Osteosarcoma Cells

Stefan Meyer, Tim Eden and Helen Kalirai
Volume: 5 | Issue: 8 | Pages: 915 - 920

Open Access Article



Commentary

Benefits and Adverse Effects of Anti-Emetic Glucocorticoids in Cancer

Ansgar Brüning and Klaus Friese
Volume: 5 | Issue: 8 | Pages: 921 - 922

Open Access Article



Brief Communication

A Proposed Clinical Test for Monitoring Fluoropyrimidine Therapy: Detection and Stability of Thymidylate Synthase Ternary Complexes

J.R. Brody, E. Gallmeier, K. Yoshimura, T. Hucl, P. Kulesza, M.I. Canto, R.H. Hruban, R.D. Schulick and S.E. Kern
Volume: 5 | Issue: 8 | Pages: 923 - 927

Open Access Article


Recurrent KRAS Codon 146 Mutations in Human Colorectal Cancer

S. Edkins, S. O’Meara, A. Parker, C. Stevens, M. Reis, S. Jones, C. Greenman, H. Davies, G. Dalgliesh, S. Forbes, C. Hunter, R. Smith, P. Stephens, P. Goldstraw, A. Nicholson, T.L. Chan, V.E. Velculescu, S.T. Yuen, S.Y. Leung, M.R. Stratton, P.A. Futreal
Volume: 5 | Issue: 8 | Pages: 928 - 932

Open Access Article



Research Paper

Dexamethasone Decreases Xenograft Response to Paclitaxel Through Inhibition of Tumor Cell Apoptosis

Diana Pang, Masha Kocherginsky, Thomas Krausz, So-Young Kim and Suzanne D. Conzen
Volume: 5 | Issue: 8 | Pages: 933 - 940

Open Access Article



Commentary

New In Vivo Results Support Concerns about Harmful Effects of Cortisone Drugs in the Treatment of Breast Cancer

Ingrid Herr and Markus W. Büchler
Volume: 5 | Issue: 8 | Pages: 941 - 942

Open Access Article



Research Paper

Impaired Cisplatin Influx in an A2780 Mutant Cell Line: Evidence for a Putative, cis-Configuration-Specific, Platinum Influx Transporter

Jozien Helleman, Herman Burger, Irene H.L. Hamelers, Antonius W.M. Boersma, Anton I.P.M. de Kroon, Gerrit Stoter and Kees Nooter
Volume: 5 | Issue: 8 | Pages: 943 - 949

Open Access Article


TRF2 Promotes Multidrug Resistance in Gastric Cancer Cells

Hanbing Ning, Tingting Li, Lina Zhao, Ting Li, Jichang Li, Jie Liu, Zhiguo Liu and Daiming Fan
Volume: 5 | Issue: 8 | Pages: 950 - 956

Open Access Article



Commentary

Resistance From The Flanks: A Role for Telomere Repeat Factor 2 in Chemotherapeutic Drug Resistance

Paul M. Lieberman
Volume: 5 | Issue: 8 | Pages: 957 - 958

Open Access Article



Research Paper

Activation of ATM and Histone H2AX Phosphorylation Induced by Mitoxantrone But Not by Topotecan is Prevented by the Antioxidant N-acetyl-L-Cysteine

Xuan Huang, Akira Kurose, Toshiki Tanaka, Frank Traganos, Wei Dai and Zbigniew Darzynkiewicz
Volume: 5 | Issue: 8 | Pages: 959 - 964

Open Access Article



Commentary

Important Differences Between Topoisomerase-I and -II Targeting Agents

Shantanu Banerji and Marek Los
Volume: 5 | Issue: 8 | Pages: 965 - 966

Open Access Article



Research Paper

Proteomic Analysis of Proteins Involved in Mitochondria-to-Nucleus Retrograde Response in Human Cancer Cells

Mariola Kulawiec, Hilal Arnouk, Mohamed Mokhtar Desouki, Latif Kazim, Ivan Still and Keshav K. Singh
Volume: 5 | Issue: 8 | Pages: 967 - 968

Open Access Article



Commentary

Understanding Mitochondrial Genetic Abnormalities in Cancer Etiology: A Proteomics Approach

Paul R. Graves
Volume: 5 | Issue: 8 | Pages: 976 - 977

Open Access Article



Research Paper

Growth Arrest Induced by C75, A Fatty Acid Synthase Inhibitor, Was Partially Modulated by p38 MAPK but not by p53 in Human Hepatocellular Carcinoma

Yan Gao, Li-Ping Lin, Cai-Hua Zhu, Fa-jun Nan, Xiong-Wen Zhang, Yi Chen, Yong-Tai Hou and Jian Ding
Volume: 5 | Issue: 8 | Pages: 978 - 985

Open Access Article



Commentary

Cancer Therapy: Back to Metabolism

Harmeet Malhi and Gregory J. Gores
Volume: 5 | Issue: 8 | Pages: 986 - 987

Open Access Article



Research Paper

Biphasic Regulation of Extracellular Signal-Regulated Kinases by Scalaradial, A Secretory Phospholipase A2 Inhibitor

Yili Xie, Zhiguo Yu, Lunhua Liu, Yuewei Guo and Liguang Lou
Volume: 5 | Issue: 8 | Pages: 988 - 992

Open Access Article


DNA Methylation Alterations in Urothelial Carcinoma

Anne Neuhausen, Andrea R. Florl, Marc-Oliver Grimm and Wolfgang A. Schulz
Volume: 5 | Issue: 8 | Pages: 993 - 1001

Open Access Article


Suppression of Human Brain Tumor with Interference RNA Specific for Tenascin-C

Ryszard Zukiel, Stanislaw Nowak, Eliza Wyszko, Katarzyna Rolle, Iwona Gawronska, Miroslawa Z. Barciszewska and Jan Barciszewski
Volume: 5 | Issue: 8 | Pages: 1002 - 1007

Open Access Article


PPARγ Activator Rosiglitazone Inhibits Cell Migration via Upregulation of PTEN in Human Hepatocarcinoma Cell Line BEL-7404

Wen Zhang, Nan Wu, Zengxia Li, Liying Wang, Jiawei Jin and Xiliang Zha
Volume: 5 | Issue: 8 | Pages: 1008 - 1014

Open Access Article


Combination of Gemcitabine Antagonizes Antitumor Activity of Paclitaxel through Prevention of Mitotic Arrest and Apoptosis

Meihua Sui, Xiaoxiong Xiong, Andrew S. Kraft and Weimin Fan
Volume: 5 | Issue: 8 | Pages: 1015 - 1021

Open Access Article


Inhibition of the CaM-Kinases Augments Cell Death in Response to Oxygen Radicals and Oxygen Radical Inducing Cancer Therapies in MCF-7 Human Breast Cancer Cells

Oswaldo G. Rodriguez-Mora, Michelle M. LaHair, Mark J. Evans, Charles J. Kovacs, Ron R. Allison, Claudio H. Sibata, Kawana S. White, James A. McCubrey and Richard A. Franklin
Volume: 5 | Issue: 8 | Pages: 1022 - 1030

Open Access Article



Commentary

A Role for CaM-Kinases in the Cellular Response to Oxidative Stress?

Vasily A. Yakovlev and Ross B. Mikkelsen
Volume: 5 | Issue: 8 | Pages: 1031 - 1032

Open Access Article



Research Paper

Differentiation of Normal Skin and Melanoma using High Resolution Hyperspectral Imaging

David T. Dicker, Jeremy Lerner, Pat Van Belle, Stephen F. Barth, DuPont Guerry, Meenhard Herlyn, David E. Elder and Wafik S. El-Deiry
Volume: 5 | Issue: 8 | Pages: 1033 - 1038

Open Access Article



Commentary

Chemokine Signaling in Gliomas: Prognostic Factor, Therapeutic Target or Both?

Ian Krop
Volume: 5 | Issue: 8 | Pages: 1039 - 1041

Open Access Article



Profiles in Science

Profiles & Legacies

Victoria L. Seewaldt
Volume: 5 | Issue: 8 | Pages: 1042 - 1045

Open Access Article