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Table of Contents

November 2006

volume 5| issue 11



Editor's Corner

Cover Image


Volume: 5 | Issue: 11

Open Access Article



News

FDA Approves Avastin in Combination with Chemotherapy for First-Line Treatment of Most Common Type of Lung Cancer


Volume: 5 | Issue: 11 | Pages: 1425 - 1426

Open Access Article


Cancer Helps Itself by Sending Out Chemicals that Cripple Nearby Lymph Nodes, Making Them Unable to Resist Cancer Spread


Volume: 5 | Issue: 11 | Page 1427

Open Access Article


Cancer Stem Cells Linked to Radiation Resistance


Volume: 5 | Issue: 11 | Page 1428

Open Access Article



Review

The Role of Apoptosis in Cancer Cell Survival and Therapeutic Outcome

Ryungsa Kim, Manabu Emi and Kazuaki Tanabe
Volume: 5 | Issue: 11 | Pages: 1429 - 1442

Open Access Article



Journal Club

Piecing Together the HIF-1 Puzzle: The Role of the CTGF as a Molecular Mechanism of HIF-1 Regulation

Erika K Smith
Volume: 5 | Issue: 11 | Pages: 1443 - 1444

Open Access Article



Brief Communication

EGFR Intron 1 Polymorphism in Asian Populations and its Correlation with EGFR Gene Expression and Amplification in Breast Tumour Tissues

Qingyu Zhou, Yin Bun Cheung, Srinivasa Rao Jada, Wan Teck Lim, Wen-Lin Kuo, Joe W. Gray, Ann SG Lee and Balram Chowbay
Volume: 5 | Issue: 11 | Pages: 1445 - 1449

Open Access Article



Research Paper

Transcriptional Activation of the Carboxylesterase 2 Gene by the p53 Pathway

Woonyoung Choi, David Cogdell, Yumei Feng, Stanley R. Hamilton, Wei Zhang
Volume: 5 | Issue: 11 | Pages: 1450 - 1456

Open Access Article


Silencing Stathmin Gene Expression by Survivin Promoter-Driven siRNA Vector to Reverse Malignant Phenotype of Tumor Cells

Hui-Zhong Zhang, Yan Wang, Ping Gao, Fang Lin, Li Liu, Bing Yu, Ji-Hong Ren, Hui Zhao and Rui Wang
Volume: 5 | Issue: 11 | Pages: 1457 - 1461

Open Access Article


Histamine-Mediated Signaling Processes in Human Malignant Mammary Cells

Vanina Medina, Graciela Cricco, Mariel Nuñez, Gabriela Martín, Nora Mohamad, Florencia Correa-Fiz, Francisca Sanchez-Jimenez, Rosa Bergoc and Elena Rivera
Volume: 5 | Issue: 11 | Pages: 1462 - 1471

Open Access Article



Commentary

Histamine: A Potential Therapeutic Agent for Breast Cancer Treatment?

Farhad Vesuna and Venu Raman
Volume: 5 | Issue: 11 | Pages: 1472 - 1473

Open Access Article



Research Paper

A New Marine-Derived Sulfated Polysaccharide from Brown Alga Suppresses Tumor Metastasis Both in Vitro and in Vivo

Xuelian Tang, Jing Li, Xianliang Xin and Meiyu Geng
Volume: 5 | Issue: 11 | Pages: 1474 - 1480

Open Access Article


Knockdown of Mutant K-ras Expression by Adenovirus-Mediated siRNA Inhibits the In Vitro and in Vivo Growth of Lung Cancer Cells

Zhiping Zhang, Guanchao Jiang, Fan Yang and Jun Wang
Volume: 5 | Issue: 11 | Pages: 1481 - 1486

Open Access Article


Suppressive Effect of Modified Dominant Negative RAS Mutant on Human Cancer by Gene Transfer with Non-Viral Vector

H Suzuki, S Kuzumaki, K Nakagawa, M Takimoto and T Shichinohe
Volume: 5 | Issue: 11 | Pages: 1487 - 1491

Open Access Article



Commentary

Dominant Negative RAS as an Anticancer Agent

Wei Guo and Bingliang Fang
Volume: 5 | Issue: 11 | Pages: 1492 - 1493

Open Access Article



Research Paper

Epigenetic Inactivation of EGFR by CpG Island Hypermethylation in Cancer

Alberto J. Montero, C. Marcela Díaz-Montero, Li Mao, Emile Youssef, Marcos Estecio, Lanlan Shen and Jean-Pierre J. Issa
Volume: 5 | Issue: 11 | Pages: 1494 - 1501

Open Access Article


Enhanced Specificity of the p53 Family Proteins-Based Adenoviral Gene Therapy in Uterine Cervical Cancer Cells with E2F1-Responsive Promoters

Jae-Jung Lee, Soyeon Kim, Young IL Yeom and Dae Seog Heo
Volume: 5 | Issue: 11 | Pages: 1502 - 1510

Open Access Article


Photochemically Mediated Delivery of AdhCMV-TRAIL Augments the TRAIL-Induced Apoptosis in Colorectal Cancer Cell Lines

Birgit Engesaeter, Anette Bonsted, Trine Lillehammer, Olav Engebraaten, Kristian Berg and Gunhild Maelandsmo
Volume: 5 | Issue: 11 | Pages: 1511 - 1520

Open Access Article



Commentary

Illuminating TRAIL Gene Therapy

Shai J. White and Christina Voelkel-Johnson
Volume: 5 | Issue: 11 | Pages: 1521 - 1522

Open Access Article



Research Paper

Furanonaphthoquinones Cause Apoptosis of Cancer Cells by Inducing the Production of Reactive Oxygen Species by the Mitochondrial Voltage-dependent Anion Channel

Kei-Ichi Hirai, Hiroki Shimada, Junko Koyama, Yukie Niwa and Shigeomi Shimizu
Volume: 5 | Issue: 11 | Pages: 1523 - 1529

Open Access Article


Sonic Hedgehog-Gli1 Signaling Pathway Might Become an Effective Therapeutic Target in Gastrointestinal Neuroendocrine Carcinomas

Takashi Shida, Mitsuko Furuya, Takashi Nikaido, Masakazu Hasegawa, Keiji Koda, Kenji Oda, Masaru Miyazaki, Takashi Kishimoto, Yukio Nakatani and Hiroshi Ishikura
Volume: 5 | Issue: 11 | Pages: 1530 - 1538

Open Access Article


The Response to Brain Tumor-Derived Growth Factors is Altered in Radioresistant Human Brain Endothelial Cells

Nancy McLaughlin, Borhane Annabi, Kwang Sik Kim, Jean-Paul Bahary, Robert Moumdjian and Richard Béliveau
Volume: 5 | Issue: 11 | Pages: 1539 - 1545

Open Access Article


hTERT/re-Caspase-3 System Induce Apoptosis in hTERT-Positive

Li-fang Yang, Yan Zhao, Liang Zeng, Jian-ping Gong and Ya Cao
Volume: 5 | Issue: 11 | Pages: 1546 - 1553

Open Access Article



Commentary

Targeting Apoptosis to Cancer via hTERT Promoter

Bingliang Fang
Volume: 5 | Issue: 11 | Pages: 1554 - 1555

Open Access Article



Research Paper

The Minimum Element of a Synthetic Peptide Required to Block Prostate Tumor Cell Migration

Thomas C Sroka, Jan Marik, Michael E Pennington and Kit S Lam
Volume: 5 | Issue: 11 | Pages: 1556 - 1562

Open Access Article



Commentary

The Chemokine Receptor CXCR4: A Homing Device for Hypoxic Cancer Cells?

Nabendu Pore and Amit Maity
Volume: 5 | Issue: 11 | Pages: 1563 - 1565

Open Access Article


Combination Therapy with Gemcitabine and 5-Fluorouracil: Unblocking the Pathways to Survivin?

John P. Plastaras and Keith A. Cengel
Volume: 5 | Issue: 11 | Pages: 1566 - 1568

Open Access Article


Naturally Occurring, Unmodified Bacterial toxin for the Treatment of Glioblastoma Multiforme?

Walter Debinski
Volume: 5 | Issue: 11 | Pages: 1569 - 1570

Open Access Article



Book Review

Vascular-Targeted Therapies in Oncology

Sydney M. Evans
Volume: 5 | Issue: 11 | Pages: 1571 - 1572

Open Access Article



Profiles and Legacies

Exploiting the Complex Biology of Prostate Cancer

Timothy C. Thompson
Volume: 5 | Issue: 11 | Pages: 1573 - 1576

Open Access Article