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Table of Contents

january 2006

volume 5| issue 1

Editor's Corner

Cover Image

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Volume: 5 | Issue: 1 | Pages: NA

Open Access Article

News

El-Deiry Recognized in 2005 by ISI as Highly Cited Over 20 Year Period in Molecular Biology and Genetics

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Volume: 5 | Issue: 1 | Page 3

Open Access Article

Involvement of Stem Cell Genes in Breast and Germ Cell Tumors

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Volume: 5 | Issue: 1 | Page 4

Open Access Article

The Tyrosine Kinase Ack1 Promotes Prostate Tumor Growth

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Volume: 5 | Issue: 1 | Page 5

Open Access Article

Visualizing an Immune Response to Cancer

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Volume: 5 | Issue: 1 | Page 5

Open Access Article

Mammaglobin as a Biomarker to Detect Breast Cancer Recurrence

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Volume: 5 | Issue: 1 | Page 6

Open Access Article

Survival Benefit in Early Stage Breast Cancer of Herceptin Plus a Chemotherapy Regimen Lacking Adriamycin

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Volume: 5 | Issue: 1 | Page 6

Open Access Article

Role of Cyclin D1/2 and CDK4/6 in Myeloma Relapse

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Volume: 5 | Issue: 1 | Page 7

Open Access Article

Activity of AMN107 in Gleevec-resistant Leukemia

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Volume: 5 | Issue: 1 | Page 8

Open Access Article

Targeting MDC1-Mediated Homologous Recombination and Repair as a Therapeutic Possibility

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Volume: 5 | Issue: 1 | Page 8

Open Access Article

Review

Cancer-Selective Therapy of the Future: Apoptin and Its Mechanism of Action

 Subbareddy Maddika, Francisco J. Mendoza, Kristin Hauff, Christina R. Zamzow, Ted Paranjothy and Marek Los
Volume: 5 | Issue: 1 | Pages: 10 - 19

Open Access Article

Journal Club

Klotho, the Long Sought-After Elixir and A Novel Tumor Suppressor?

 Y. Alan Wang
Volume: 5 | Issue: 1 | Pages: 20 - 21

Open Access Article

Clinical Trials

Phase I Clinical Trial of Oral 2-Methoxyestradiol, an Antiangiogenic and Apoptotic Agent, in Patients with Solid Tumors

 William L. Dahut, Nehal J. Lakhani, James L. Gulley, Philip M. Arlen, Elise C. Kohn, Herbert Kotz, Debbie McNally, Allyson Parr, Diana Nguyen, Sherry X. Yang, Seth M. Steinberg, Jürgen Venitz, Alex Sparreboom and William D. Figg
Volume: 5 | Issue: 1 | Pages: 22 - 27

Open Access Article

Research Paper

Expression and Functional Analysis of Platelet-Derived Growth Factor in Uterine Leiomyomata

 Minglin Liang, Hongbo Wang, Yuan Zhang, Shi Lu and Zehua Wang
Volume: 5 | Issue: 1 | Pages: 28 - 33

Open Access Article

Use of the 13C-Sucrose Breath Test to Assess Chemotherapy-Induced Small Intestinal Mucositis in the Rat

 Julie M. Clarke, Nicole C Pelton, Balazs H. Bajka, Gordon S. Howarth, Leanna C. Read and Ross N. Butler
Volume: 5 | Issue: 1 | Pages: 34 - 38

Open Access Article

Reversal of MDR1/P-Glycoprotein-Mediated Multidrug Resistance by Vector-Based RNA Interference In Vitro and In Vivo

 Zhi Shi, Yong-ju Liang, Zhe-sheng Chen, Xiu-wen Wang, Xiao-hong Wang, Yan Ding, Li-ming Chen, Xiao-ping Yang and Li-wu Fu
Volume: 5 | Issue: 1 | Pages: 39 - 47

Open Access Article

Cisplatin-Induced GADD34 Upregulation Potentiates Oncolytic Viral Therapy in the Treatment of Malignant Pleural Mesothelioma

 Prasad S. Adusumilli, Mei-Ki Chan, Yun Shin Chun, Michael Hezel, Ting-Chao Chou, Valerie W. Rusch and Yuman Fong
Volume: 5 | Issue: 1 | Pages: 48 - 53

Open Access Article

Identification of Genes Downregulated in Tumor Cells Expressing Antisense Glutaminase mRNA by Differential Display

 Mercedes Martín-Rufián, Juan A. Segura, Carolina Lobo, José M. Matés, Javier Márquez and Francisco J. Alonso
Volume: 5 | Issue: 1 | Pages: 54 - 58

Open Access Article

Corticosteriod-Induced Chemotherapy Resistance in Urological Cancers

 C. Zhang, J. Mattern, A. Haferkamp, J. Pfitzenmaier, M. Hohenfellner, W. Rittgen, L Edler, K.-M. Debatin, E. Groene and I. Herr
Volume: 5 | Issue: 1 | Pages: 59 - 64

Open Access Article

Loss of DNA Methylation and Histone H4 Lysine 20 Trimethylation in Human Breast Cancer Cells is Associated with Aberrant Expression of DNA Methyltransferase 1, Suv4-20h2 Histone Methyltransferase and Methyl-Binding Proteins

 Volodymyr P. Tryndyak, Olga Kovalchuk and Igor P. Pogribny
Volume: 5 | Issue: 1 | Pages: 65 - 70

Open Access Article

The Role of Relaxin in Endometrial Cancer

 Aparna A. Kamat, Shu Feng, Irina U. Agoulnik, Farrah Kheradmand, Natalia V. Bogatcheva, Donna Coffey, Anil K. Sood and Alexander I. Agoulnik
Volume: 5 | Issue: 1 | Pages: 71 - 77

Open Access Article

CDC4 Gene Expression as Potential Biomarker for Targeted Therapy in Prostate Cancer

 Moon S. Koh, Michael Ittmann, Dov Kadmon, Timothy Thompson and Fredrick S. Leach
Volume: 5 | Issue: 1 | Pages: 78 - 83

Open Access Article

pRb2/p130 and VEGF Expression in Endometrial Carcinoma in Relation to Angiogenesis and Histopathologic Tumor Grade

 Francesca Sanseverino, Rosa Santopietro, Michela Torricelli, Giuseppina D’Andrilli, Giuseppe Russo, Gabriele Cevenini, Alessandro Bovicelli, Lorenzo Leoncini, Giovanni Scambia, Felice Petraglia, Pier Paolo Claudio and Antonio Giordano
Volume: 5 | Issue: 1 | Pages: 84 - 88

Open Access Article

Paclitaxel Encapsulated in Cationic Lipid Complexes (MBT-0206) Impairs Functional Tumor Vascular Properties as Detected by Dynamic Contrast Enhanced Magnetic Resonance Imaging

 M.E. Eichhorn, S. Becker, S. Strieth, A. Werner, B. Sauer, M. Teifel, H. Ruhstorfer, U. Michaelis, J. Griebel, G. Brix, K.-W. Jauch and M. Dellian
Volume: 5 | Issue: 1 | Pages: 89 - 96

Open Access Article

Cytotoxicity of a Natural Anthraquinone (Aloin) Against Human Breast Cancer Cell Lines with and without ErbB-2: Topoisomerase II? Coamplification

 Amr Y. Esmat,Catherine Tomasetto and Marie-Christine Rio
Volume: 5 | Issue: 1 | Pages: 97 - 103

Open Access Article

Differential Gene Expression Profiling in Aggressive Bladder Transitional Cell Carcinoma Compared to the Adjacent Microscopically Normal Urothelium by Microdissection-SMART cDNA PCR-SSH

 H.T. Wang, F.L. Ma, X.B. Ma, R.F.Han, Y.B. Zhang and J.W. Chang
Volume: 5 | Issue: 1 | Pages: 104 - 110

Open Access Article

Hedgehog Signaling in Human Hepatocellular Carcinoma

 Mohini A. Patil, Ji Zhang, Coral Ho, Siu-Tim Cheung, Sheung-Tat Fan and Xin Chen
Volume: 5 | Issue: 1 | Pages: 111 - 117

Open Access Article

Commentary

Targeted Radiation for Melanoma: Alpha Therapy Prepares for a Beta Test

 Peter Roberson and Joseph N. Contessa
Volume: 5 | Issue: 1 | Pages: 118 - 119

Open Access Article

Profiles in Science

Such An Obsession

 David P. Lane
Volume: 5 | Issue: 1 | Pages: 120 - 123

Open Access Article