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Table of Contents

April 2005

volume 4| issue 4



News

BDNF as a Target to Modulate Angiogenesis

n/a
Volume: 4 | Issue: 4 | Pages: i

Open Access Article


Educated T-Cells Mount Stronger Anti-Tumor Response in Myeloma

n/a
Volume: 4 | Issue: 4 | Pages: ii

Open Access Article


Small Molecule Targeting Stat3 Activity in Breast Cancer

NA
Volume: 4 | Issue: 4 | Pages: ii

Open Access Article


Timing of Vaccine Therapy May be Important in Prostate Cancer

NA
Volume: 4 | Issue: 4 | Pages: iii

Open Access Article


Retro-Transposons Provide Clues to Genomic Instability in a Yeast Model

NA
Volume: 4 | Issue: 4 | Pages: iii

Open Access Article


EBV Nuclear Protein EBNA3C Jump Starts the Cell Cycle Leading to Uncontrolled Growth

NA
Volume: 4 | Issue: 4 | Pages: iv

Open Access Article


Tel2 Cooperates with Myc in B-Cell Lymphomagenesis by Inactivating p53

N/A
Volume: 4 | Issue: 4 | Pages: iv

Open Access Article


Stanley J. Korsmeyer, 1950-2005

NA
Volume: 4 | Issue: 4 | Pages: v

Open Access Article



Editor's Corner

Cover Image

NA
Volume: 4 | Issue: 4 | Pages: NA

Open Access Article



Correspondence

EpCAM is not a LAIR-1 ligand!

Andreas Nechansky and Ralf Kircheis
Volume: 4 | Issue: 4 | Pages: 357-357

Open Access Article


EpCAM is an Important Suppressor of Anti-Tumor Immunity

Stephen L. Eck and Andrew Armstrong
Volume: 4 | Issue: 4 | Pages: 358-358

Open Access Article



Review

Achieving Hypoxia-Inducible Gene Expression in Tumours

L. Marignol, M. Lawler and D. Hollywood
Volume: 4 | Issue: 4 | Pages: 359-364

Open Access Article


The Epithelial-Mesenchymal Transition (EMT) and Colorectal Cancer Progression

Richard C. Bates and Arthur M. Mercurio
Volume: 4 | Issue: 4 | Pages: 365-370

Open Access Article



Bedside to Bench

Prostate Specific Antigen as a Clinical Biomarker for Prostate Cancer: What’s the Take Home Message?

Frederick S. Leach, Moon S. Koh, Yung W. Chan, Samantha Bark, Robert Ray , Ronald A. Morton and Alan T. Remaley
Volume: 4 | Issue: 4 | Pages: 371-375

Open Access Article



Journal Club

A Novel WISp39 Protein Links Hsp90 and p21 Stability to the G2/M Checkpoint

Sharon Benzeno and J. Alan Diehl
Volume: 4 | Issue: 4 | Pages: 376-378

Open Access Article



Brief Communication

Signal Therapy of NF1-deficient Tumor Xenograft in Mice by the Anti-PAK1 Drug FK228

Yumiko Hirokawa, Hidenori Nakajima, C. Oliver Hanemann, Andreas Kurtz, Silke Frahm, Victor Mautner and Hiroshi Maruta
Volume: 4 | Issue: 4 | Pages: 379-381

Open Access Article



Research Paper

Trichostatin A (TSA) Sensitizes the Human Prostatic Cancer Cell Line DU145 to Death Receptor Ligands Treatment

Agshin F. Taghiyev, Natalya V. Guseva, Mary T. Sturm, Oskar W. Rokhlin and Michael B. Cohen
Volume: 4 | Issue: 4 | Pages: 382-390

Open Access Article



Commentary

Exploiting the TSA Connections to Overcome Apoptosis-Resistance

Padhma Ranganathan and Vivek M. Rangnekar
Volume: 4 | Issue: 4 | Pages: 391-392

Open Access Article



Research Paper

Enhancing TRAIL-Induced Apoptosis by Bcl-XL siRNA

Hongbo Zhu, Wei Guo, Lidong Zhang, John J. Davis, Shuhong Wu, Fuminori Teraishi, Xiaobo Cao, W. Roy Smythe and Bingliang Fang
Volume: 4 | Issue: 4 | Pages: 393-397

Open Access Article



Commentary

Silencing Bcl-XL in Cancer Therapy

Kunhong Kim
Volume: 4 | Issue: 4 | Pages: 398-399

Open Access Article



Research Paper

Maspin Regulates Hypoxia-Mediated Stimulation of uPA/uPAR Complex in Invasive Breast Cancer Cells

Sumaira Amir, Naira.V. Margaryan, Valerie Odero- Marah, Zhila Khalkhali-Ellis and Mary J.C. Hendrix
Volume: 4 | Issue: 4 | Pages: 400-406

Open Access Article


Enhanced Growth Inhibition and Apoptosis Induction in NSCLC Cell Lines by Combination of Celecoxib and 4HPR at Clinically Relevant Concentrations

Shi-Yong Sun, Claudia P. Schroeder, Ping Yue, Dafna Lotan, Waun K. Hong and Reuben Lotan
Volume: 4 | Issue: 4 | Pages: 407-413

Open Access Article


The Tumor Suppressor Protein p53 Functions Similarly to p63 and p73 in Activating Transcription In Vitro

Neelima Mondal and Jeffrey D. Parvin
Volume: 4 | Issue: 4 | Pages: 414-418

Open Access Article



Commentary

p53 Family Members: Similar Biochemistry, Different Biology

Christopher E. Barbieri and Jennifer A. Pietenpol
Volume: 4 | Issue: 4 | Pages: 419-420

Open Access Article



Research Paper

Augmentation of Antitumor Effects of p53 Gene Therapy by Combination with HDAC Inhibitor

Rishu Takimoto, Junji Kato, Takeshi Terui, Koichi Takada, Ganji Kuroiwa, Jing Wu, Hiroyuki Ohnuma, Daisuke Takahari, Masayoshi Kobune, Yasushi Sato, Tetsuji Takayama, Takuya Matsunaga and Yoshiro Niitsu
Volume: 4 | Issue: 4 | Pages: 421-428

Open Access Article



Commentary

Nuclear Localization of RFC40 by RIα: A Link between Cellular Signaling and Proliferation

Neerja Karnani and Anindya Dutta
Volume: 4 | Issue: 4 | Pages: 438-439

Open Access Article



Research Paper

RIα Influences Cellular Proliferation in Cancer Cells by Transporting RFC40 into the Nucleus

Rakhee S. Gupte, Piotr Pozarowski, Jerzy Grabarek, Frank Traganos, Zbigniew Darzynkiewicz and Marietta Y. W. T. Lee
Volume: 4 | Issue: 4 | Pages: 439-437

Open Access Article


A DNA Repeat, NBL2, is Hypermethylated in Some Cancers but Hypomethylated in Others

Rie Nishiyama, Lixin Qi, Koji Tsumagari, Karen Weissbecker, Louis Dubeau, Martin Champagne, Suresh Sikka, Hisaki Nagai and Melanie Ehrlich
Volume: 4 | Issue: 4 | Pages: 440-448

Open Access Article


Aberrant Laminin Beta-3 Isoforms Downstream of EWS-ETS Fusion Genes in Ewing Family Tumors

Hideto Irifune, Hiroyuki Nishimori, Goichi Watanabe, Kouichi Yoshida, Tatsuru Ikeda, Chihiro Matsui, Masaaki Morohashi, Satoshi Kawaguchi, Satoshi Nagoya, Takuro Wada, Toshihiko Yamashita, Yusuke Nakamura and Takashi Tokino
Volume: 4 | Issue: 4 | Pages: 449-455

Open Access Article



Commentary

Looking Downstream of Sarcoma-Associated Chimeric Transcription Factors: When is a Target Really a Target?

Gabriela E. Mercado, Frederic G. Barr
Volume: 4 | Issue: 4 | Pages: 456-458

Open Access Article



Research Paper

Bax and Bak are Required for Cytochrome c Release During Arsenic Trioxide-Induced Apoptosis

Leta K. Nutt, Vladimir Gogvadze, Wanlaya Uthaisang, Banafsheh Mirnikjoo, David J. McConkey and Sten Orrenius
Volume: 4 | Issue: 4 | Pages: 459-467

Open Access Article


Reversal of Multidrug Resistance in KB Cells with Tea Polyphenol Antioxidant Capacity

Dr. Yuying Mei, Dr. Dongzhi We and Dr. Jianwen Liu
Volume: 4 | Issue: 4 | Pages: 468-473

Open Access Article


Natural Retinoids Inhibit Proliferation and Induce Apoptosis in Pancreatic Cancer Cells Previously Reported to be Retinoid Resistant

Tarek H. El-Metwally, Mahmoud R. Hussein, Parviz M. Pour, Charles A. Kuszynski and Thomas E. Adrian
Volume: 4 | Issue: 4 | Pages: 474-483

Open Access Article


Kinase-Addiction and Bi-Phasic Sensitivity-Resistance of Bcr-Abl- and Raf-1-Expressing Cells to Imatinib and Geldanamycin

Zoya N. Demidenko, Won G. An, John T. Lee, Larisa Y. Romanova, James A. McCubrey and Mikhail V. Blagosklonny
Volume: 4 | Issue: 4 | Pages: 484-490

Open Access Article



Commentary

Velcade Displays Promising Activity in Primary Effusion Lymphoma Cells

David McConkey, Steffan T. Nawrocki and Robert Andtbacka
Volume: 4 | Issue: 4 | Pages: 491-492

Open Access Article



Profiles in Science

Why Cancer Centers Matter

Judith C. Gasson
Volume: 4 | Issue: 4 | Pages: 493-495

Open Access Article