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Table of Contents

march 2005

volume 4| issue 3



News

AMN107, A Designed Bcr-Abl Inhibitor Effective in Gleevec-Resistant CML

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Volume: 4 | Issue: 3 | Pages: i

Open Access Article


Green Tea Extract Stimulates Rho Signaling and Cell Adhesion

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Volume: 4 | Issue: 3 | Pages: i

Open Access Article


Stat5, a Favorable Marker in Breast Cancer, Suppresses Invasion and Aggressive Growth of Breast Cancer Cells

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Volume: 4 | Issue: 3 | Pages: ii

Open Access Article


Making Biological Sense May Help Reduce Noise in Serum Proteomic Tests

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Volume: 4 | Issue: 3 | Pages: iii

Open Access Article


A Rapid Tumor Marker Assay Detects NMP22 in Urine

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Volume: 4 | Issue: 3 | Pages: iii

Open Access Article


APC8015, a Therapeutic Vaccine for Prostate Cancer, Targets Prostatic Acid Phosphatase

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Volume: 4 | Issue: 3 | Pages: iv

Open Access Article


Epigenetics, IGF2 Dosage and Cancer Risk

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Volume: 4 | Issue: 3 | Pages: iv

Open Access Article


Second Mutations in EGFR Provide Clues to Acquired Resistance to Iressa and Tarceva

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Volume: 4 | Issue: 3 | Pages: v

Open Access Article


Mcl-1, Which Can Prevent Leukemia Cell Death, is Necessary for Bone Marrow Stem Cell Survival

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Volume: 4 | Issue: 3 | Pages: vi

Open Access Article


High Response Rate to Bexxar in Advanced Stage Prior Treatment-Resistant Follicular Lymphoma

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Volume: 4 | Issue: 3 | Pages: vii

Open Access Article


Link between Histone Deubiquitination and Protection of Telomeres

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Volume: 4 | Issue: 3 | Pages: viii

Open Access Article


Direct Instillation of Topotecan into Brain Tumors is Part of Experimental Protocol

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Volume: 4 | Issue: 3 | Pages: viii

Open Access Article


Elastic Light-Scattering Fingerprinting under Study for Early Detection

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Volume: 4 | Issue: 3 | Pages: ix

Open Access Article


Rate of Proliferation (Versus Death) May be Significant in B-Cell CLL

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Volume: 4 | Issue: 3 | Pages: x

Open Access Article



Editor's Corner

Cover Image

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Volume: 4 | Issue: 3 | Pages: NA

Open Access Article



Review

Targeting TGF Beta Signaling for Cancer Therapy

Sravisht Iyer, Zhen-Guo Wang, Mojtaba Akhtari, Wenli Zhao, Prem Seth
Volume: 4 | Issue: 3 | Pages: 261 - 266

Open Access Article



Research Paper

Mcl-1 Regulates Survival and Sensitivity to Diverse Apoptotic Stimuli in Human Non-Small Cell Lung Cancer Cells

Lanxi Song, Domenico Coppola, Sandy Livingston, Doug Cress, Eric B. Haura
Volume: 4 | Issue: 3 | Pages: 267 - 276

Open Access Article


Cdk9 Regulates Neural Differentiation and its Expression Correlates with the Differentiation Grade of Neuroblastoma and PNET Tumors

Giulia De Falco, Cristiana Bellan, Alessandro D'Amuri, Giuseppina Angeloni, Eleonora Leucci, Antonio Giordano, Lorenzo Leoncini
Volume: 4 | Issue: 3 | Pages: 277 - 281

Open Access Article


Genetic Response to DNA Damage: Proapoptotic Targets of RhoB Include Modules for p53 Response and Susceptibility to Alzheimer’s Disease

Uma Kamasani and George C. Prendergast
Volume: 4 | Issue: 3 | Pages: 282 - 288

Open Access Article


High Efficiency Transduction of Dendritic Cells by Adenoviral Vectors Targeted to DC-SIGN

Nikolay Korokhov, Tanja D. de Gruijl, Wayne A. Aldrich, Pierre L. Triozzi, Papia T. Banerjee, Stephen D. Gillies, Tyler J. Curiel, Joanne T. Douglas|, Rik J. Scheper, David T. Curiel
Volume: 4 | Issue: 3 | Pages: 289 - 294

Open Access Article


The Potent Inhibitory Effects of Cisapride, a Specific Blocker for Human Ether-A-Go-Go-Related Gene (HERG) Channel, on Gastric Cancer Cells

Xiao-Dong Shao, Kai-Chun Wu, Zhi-Ming Hao, Liu Hong, Jing Zhang, Dai-Ming Fan
Volume: 4 | Issue: 3 | Pages: 295 - 301

Open Access Article


Stromal Responses to Carcinomas of the Pancreas: Juxtatumoral Gene Expression Conforms to the Infiltrating Pattern and Not the Biologic Subtype

Francesca Ricci, Scott E. Kern, Ralph H. Hruban, Christine A. Iacobuzio-Donahue
Volume: 4 | Issue: 3 | Pages: 302 - 307

Open Access Article


A Novel DNA Vaccine Containing 4 Mimicry Epitopes for Gastric Cancer

Yu Chen, Kaichun Wu, Changcun Guo, Changjiang Liu, Shuang Han, Tao Lin, Xiaoxuan Ning, Rui Shi, Yongquan Shi, Daiming Fan
Volume: 4 | Issue: 3 | Pages: 308 - 312

Open Access Article


Inhibition of P-Glycoprotein-Mediated Multidrug Resistance by Unfractionated Heparin: A New Potential Chemosensitizer for Cancer Therapy

Antonio Angelini, Concetta Di Febbo, Giuliano Ciofani, Marcello Di Nisio, Giovanna Baccante, Carmine Di Ilio, Franco Cuccurullo and Ettore Porreca
Volume: 4 | Issue: 3 | Pages: 313 - 317

Open Access Article


Growth Inhibition of Head and Neck Squamous Carcinoma Cells by Small Interfering RNAs Targeting eIF4E or Cyclin D1 Alone or Combined with Cisplatin

Nobuhiko Oridate, Hyun-Jung Kim, Xiaochun Xu, Reuben Lotan
Volume: 4 | Issue: 3 | Pages: 318 - 323

Open Access Article


Analysis of the Bcl-2 and p53 Protein Expression in the Lymphoproliferative Lesions in the Upper Egypt

Mahmoud R. Hussein, Tarek M. Al-Sabae, Marcelle N. Georgis
Volume: 4 | Issue: 3 | Pages: 324 - 328

Open Access Article


Decreased Glycolytic Metabolism Accelerates Apoptosis in Response to 2-Acetyl Furanonaphthoquinone in K1735 Melanoma Irrespective of bcl-2 Overexpression

Leobaldo Solórzano, Mary Strasberg Rieber, Jose D. Medina and Manuel Rieber
Volume: 4 | Issue: 3 | Pages: 329 - 335

Open Access Article


Fragmentation and Rapid Shortening of Telomere in HeLa Cells in the Early Phase of Hydroxyl Radical-Induced Apoptosis

Lan Shao, Qing-Huan Li, Jing Wang, Zheng Tan
Volume: 4 | Issue: 3 | Pages: 336 - 341

Open Access Article


Regulatory T Cells and Cytokines in Malignant Pleural Effusions Secondary to Mesothelioma and Carcinoma

Peter DeLong, Richard G. Carroll, Adam C. Henry, Tomoyuki Tanaka, Sajjad Ahmad, Michael S. Leibowitz, Daniel H. Sterman, Carl H. June, Steven M. Albelda and Robert H. Vonderheide
Volume: 4 | Issue: 3 | Pages: 342 - 346

Open Access Article



Commentary

MTAP Homozygous Deletion: An Achilles Heel of Human Cancers Ready for Clinical Use?

Gabriel Capella, Carlos Caldas
Volume: 4 | Issue: 3 | Page 347

Open Access Article



Profiles in Science

Better to Give than Receive: My Exciting Journey in Science

Leland W. K. Chung
Volume: 4 | Issue: 3 | Pages: 348 - 352

Open Access Article