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Table of Contents

november/december 2002

volume 1| issue 6



Editor's Corner

In This Issue

Jeffrey. D. Parvin
Volume: 1 | Issue: 6 | Pages: 595 - 596

Open Access Article


Cover Image

NA
Volume: 1 | Issue: 6 | Pages: 595 - 596

Open Access Article



Review

Ras Family Signaling: Therapeutic Targeting

Adirenne D. Cox and Channing J. Der
Volume: 1 | Issue: 6 | Pages: 599 - 606

Open Access Article


An Introduction to Pancreatic Adenocarcinoma Genetics, Pathology and Therapy

Scott E. Kern, Ralph H. Hruban, Manuel Hidalgo and Charles J. Yeo
Volume: 1 | Issue: 6 | Pages: 607 - 613

Open Access Article


Treatment of Acute Promyelocytic Leukemia with ATRA and As2O3: A Model of Molecular

Jing Fang, Sai-Juan Chen, Jian-Hua Tong, Zhu-Gang Wang, Guo-Qiang Chen and
Volume: 1 | Issue: 6 | Pages: 614 - 620

Open Access Article


b-Catenin Signaling: Therapeutic Strategies in Oncology

Han Li, Rifat Pamukcu and W. Joseph Thomson
Volume: 1 | Issue: 6 | Pages: 621 - 625

Open Access Article



Exegeses and Views

Ribavirin in Cancer Immunotherapies Controlling Nitric Oxide Helps Generate Cytotoxic Lymphocyte

R.E. Kast
Volume: 1 | Issue: 6 | Pages: 626 - 630

Open Access Article



Research Paper

TRAIL-DISC Formation Is Androgen-Dependent in the Human Prostatic Carcinoma Cell Line LNCaP

Oskar W. Rokhlin, Agshin F. Taghiyev, Nataliya V. Guseva, Rebecca A. Glover, Sergei I. Syrbu and Michael B. Cohen
Volume: 1 | Issue: 6 | Pages: 631 - 637

Open Access Article



Commentary

On the TRAIL from Death Receptors to Prostate Cancer Therapy

Atul Bedi
Volume: 1 | Issue: 6 | Pages: 638 - 639

Open Access Article



Research Paper

Developmental Expression of Wnt Signaling Factors in Mouse Brain

Jacquelyn Coyle-Rink, Luis Del Valle, Thersa Sweet, Kamel Khalili and Shohreh Amini
Volume: 1 | Issue: 6 | Pages: 640 - 645

Open Access Article


Phase I Dose Escalation Trial of Weekly Docetaxel Plus Irinotecan in Patients with Advanced Cancer

Eric Bleickardt, Athanassios Argiris, Randy Rich, Kathi Blum, Anne McKeon, Harold Tara, Daniel Zelterman, Barbara Burtness, Marianne J. Davies and John R. Murren
Volume: 1 | Issue: 6 | Pages: 646 - 651

Open Access Article


Role of MRIT/cFLIP in Protection Against Chemotherapy-Induced Apoptosis

Hittu Matta, Michael T. Eby, Adi F. Gazdar and Preet M. Chaudhary
Volume: 1 | Issue: 6 | Pages: 652 - 660

Open Access Article


The Clinical Significance of Tumor Cell-Lined Vasculature in Ovarian Carcinoma: Implications for Anti-Vasculogenic Therapy

Anil K. Sood, Mavis S. Fletcher, Chris M. Zahn, Lynn M. Gruman, Jeremy E. Coffin, Elisabeth A. Seftor and Mary J.C. Hendrix
Volume: 1 | Issue: 6 | Pages: 661 - 664

Open Access Article


The Histone Deacetylase Inhibitor FR901228 (Depsipeptide) Restores Expression and Function of Pseudo-Null p53

Masaki Kitazono, Susan Bates, Patrick Fok, Tito Fojo and Mikhail V. Blagosklonny
Volume: 1 | Issue: 6 | Pages: 665 - 668

Open Access Article


Pharmacogenetic Associations of CYP2C19 Genotype with In Vivo Metabolisms and Pharmacological Effects of Thalidomide

Yuichi Ando, Douglas K. Price, William L. Dahut2, Michael C. Cox, Eddie Reed and William D. Figg
Volume: 1 | Issue: 6 | Pages: 669 - 673

Open Access Article


Coadministration of UCN-01 with MEK1/2 Inhibitors Potently Induces Apoptosis in

Chunrong Yu, Yun Dai, Paul Dent and Steven Grant
Volume: 1 | Issue: 6 | Pages: 674 - 682

Open Access Article



Commentary

Beyond Directed Therapeutics: Are Two Drugs Always Better than One?

Martin Carroll
Volume: 1 | Issue: 6 | Pages: 683 - 684

Open Access Article



Research Paper

Dynamics of Genetic Instability in Sporadic and Familial Colorectal Cancer

Natalia L. Komarova, Christoph Lengauer, Bert Vogelstein and Martin A. Nowak
Volume: 1 | Issue: 6 | Pages: 685 - 692

Open Access Article


Single-Nucleotide Polymorphism (SNP) Analysis in the ABC Half-Transporter ABCG2 (MXR/BCRP/ABCP1)

Yasumasa Honjo, Kuniaki Morisaki, Lyn Mickley Huff, Robert W. Robey, Jeffrey Hung, Michael Dean and Susan E. Bates
Volume: 1 | Issue: 6 | Pages: 696 - 702

Open Access Article


Lyn Tyrosine Kinase Inhibits Nuclear Export of the p53 Tumor Suppressor

Xinping Ren, Cheng Cao, Liben Zhu, Kiyotsugu Yoshida, Surender Kharbanda, Ralph Weichselbaum and Donald Kufe
Volume: 1 | Issue: 6 | Pages: 703 - 708

Open Access Article



Commentary

Lyn: One More Actor in the p53 Cast?

Baskaran Rajasekaran
Volume: 1 | Issue: 6 | Pages: 709 - 710

Open Access Article



Research Philosophy

From the War on Cancer to Translational Oncology

Mikhail V. Blagosklonny
Volume: 1 | Issue: 6 | Pages: 711 - 714

Open Access Article



Profiles in Science

Fifty Years in Cancer Research

Peter C. Nowell
Volume: 1 | Issue: 6 | Pages: 715 - 717

Open Access Article


Translational Research: Stop, Look, Listen—If You Expect to Grow Up Tall

Daniel D. Von Hoff
Volume: 1 | Issue: 6 | Pages: 718 - 720

Open Access Article



Book Review

Targeting and Delivering Therapeutic Genes

Wafik S. El-Deiry
Volume: 1 | Issue: 6 | Pages: 721 - 723

Open Access Article