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Journal Club
Histone Deacetylase Inhibitors are Potent Radiation Protectants
Luca Paoluzzi and William D. Figg
volume 3 | issue 7
july 2004Pages: 612-613
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Radiation-induced acute and late injuries often represent a limit to the optimal delivery of radiotherapy in cancer patients. Chung et al. reported that histone deacetylase (HDAC) inhibitors, a novel class compound of gene modulators, might have a role in controlling different adverse effects from radiotherapy in pre-clinical models. They also showed how protection of normal tissues and inhibition of tumor growth might be possible at the same time.
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDFIf the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.