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Journal Club

Ubiquitin-Dependent Activation of NF-kappaB: K63-Linked Ubiquitin Chains—a Link to Cancer?

Zhijian J. Chen and Serge Y. Fuchs

volume 3 | issue 3

mar 2004
Pages: 286-288

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Recent discoveries of the novel roles of lysine 63–linked polyubiquitin chains in the activation of NF-?B transcription factor shed new light on both the mechanistic aspects of this signal transduction pathway and its role in cancer.




We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:

 Download PDF

If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.