Recommend Autophagy to your librarian for 2008. Download form here. Sign up for Table of Contents Alerts! Table of Contents 16 February 2008 volume 4| issue 2

Editor's Corner

Getting into the flow

Daniel J. Klionsky
Volume: 4 | Issue: 2 | Pages: 139 - 140

Review

Sorting, recognition and activation of the misfolded protein degradation pathways through macroautophagy and the proteasome

Wen-Xing Ding and Xiao-Ming Yin
Volume: 4 | Issue: 2 | Pages: 141 - 150

Open Access Article

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky, Hagai Abeliovich, Patricia Agostinis, Devendra K. Agrawal, Gjumrakch Aliev, David S. Askew, Misuzu Baba, Eric H. Baehrecke, Ben A. Bahr, Andrea Ballabio, Bruce A. Bamber, Diane C. Bassham, Ettore Bergamini, Xiaoning Bi, Martine Biard-Piechaczyk, Janice S. Blum, Dale E. Bredesen, Jeffrey L. Brodsky, John H. Brumell, Ulf T. Brunk, Wilfried Bursch, Nadine Camougrand, Eduardo Cebollero, Francesco Cecconi, Yingyu Chen, Lih-Shen Chin, Augustine Choi, Charleen T. Chu, Jongkyeong Chung, Robert S.B. Clark, Peter G.H. Clarke, Steven G. Clarke, Corinne Clave, John L. Cleveland, Patrice Codogno, Marí­a I. Colombo, Ana Coto-Montes, James M. Cregg, Ana Maria Cuervo, Jayanta Debnath, Patrick B. Dennis, Phillip A. Dennis, Francesca Demarchi, Vojo Deretic, Rodney J. Devenish, Federica Di Sano, J. Fred Dice, Clark W. Distelhorst, Savithramma Dinesh-Kumar, N. Tony Eissa, Marian DiFiglia, Mojgan Djavaheri-Mergny, Frank C. Dorsey, Wulf Dröge, Michel Dron, William A. Dunn, Jr., Michael Duszenko, Zvulun Elazar, Audrey Esclatine, Eeva-Liisa Eskelinen, László Fésüs, Kim D. Finley, José M. Fuentes, Juan Fueyo, Kozo Fujisaki, Brigitte Galliot, Fen-Biao Gao, David A. Gewirtz, Spencer B. Gibson, Antje Gohla, Alfred L. Goldberg, Ramon Gonzalez, Cristina González-Estévez, Sharon Gorski, Roberta A. Gottlieb, Dieter Häussinger, You-Wen He, Kim Heidenreich, Joseph A. Hill, Maria Høyer-Hansen, Xun Hu, Wei-Pang Huang, Akiko Iwasaki, Marja Jäättelä, William T. Jackson, Xuejun Jiang, Shengkan Jin, Terje Johansen, Jae U. Jung, Motoni Kadowaki, Chanhee Kang, Ameeta Kelekar, David H. Kessel, Jan A.K.W. Kiel, Hong Pyo Kim, Adi Kimchi, Timothy J. Kinsella, Kirill Kiselyov, Katsuhiko Kitamoto, Erwin Knecht, Masaaki Komatsu, Eiki kominami, Seiji Kondo, Attila L. Kovács, Guido Kroemer, Chia-Yi Kuan, Rakesh Kumar, Mondira Kundu, Jacques Landry, Marianne Laporte, Weidong Le, Huan-Yao Lei, Beth Levine, Andrew Lieberman, Kah-Leong Lim, Fu-Cheng Lin, Willisa Liou, Leroy F. Liu, Gabriel Lopez-Berestein, Carlos López-Otín, Bo Lu, Kay F. Macleod, Walter Malorni, Wim Martinet, Ken Matsuoka, Josef Mautner, Alfred J. Meijer, Alicia Meléndez, Paul Michels, Giovanni Miotto, Wilhelm P. Mistiaen, Noboru Mizushima, Baharia Mograbi, Michael N. Moore, Paula I. Moreira, Yuji Moriyasu, Tomasz Motyl, Christian Münz, Leon O. Murphy, Naweed I. Naqvi, Thomas P. Neufeld, Ichizo Nishino, Ralph A. Nixon, Takeshi Noda, Bernd Nürnberg, Michinaga Ogawa, Nancy L. Oleinick, Laura J. Olsen, Bulent Ozpolat, Shoshana Paglin, Glen E. Palmer, Issidora S. Papassideri, Miles Parkes, David H. Perlmutter, George Perry, Mauro Piacentini, Ronit Pinkas-Kramarski, Mark Prescott, Tassula Proikas-Cezanne, Nina Raben, Abdelhaq Rami, Fulvio Reggiori, Bärbel Rohrer, David C. Rubinsztein, Kevin M. Ryan, Junichi Sadoshima, Hiroshi Sakagami, Yasuyoshi Sakai, Marco Sandri, Chihiro Sasakawa, Miklós Sass, Claudio Schneider, Per O. Seglen, Oleksandr Seleverstov, Jeffrey Settleman, John J. Shacka, Irving M. Shapiro, Andrei A. Sibirny, Elaine C.M. Silva-Zacarin, Hans-Uwe Simon, Cristiano Simone, Anne Simonsen, Mark A. Smith, Katharina Spanel-Borowski, Vickram Srinivas, Meredith Steeves, Harald Stenmark, Per E. Stromhaug, Carlos S. Subauste, Seiichiro Sugimoto, David Sulzer, Toshihiko Suzuki, Michele S. Swanson, Ira Tabas, Fumihiko Takeshita, Nicholas J. Talbot, Zsolt Tallóczy, Keiji Tanaka, Kozo Tanaka, Isei Tanida, Graham S. Taylor, J. Paul Taylor, Alexei Terman, Gianluca Tettamanti, Craig B. Thompson, Michael Thumm, Aviva M. Tolkovsky, Sharon A. Tooze, Ray Truant, Lesya V. Tumanovska, Yasuo Uchiyama, Takashi Ueno, Néstor L. Uzcátegui, Ida J. van der Klei, Eva C. Vaquero, Tibor Vellai, Michael W. Vogel, Hong-Gang Wang, Paul Webster, Zhijun Xi, Gutian Xiao, Joachim Yahalom, Jin-Ming Yang, George S. Yap, Xiao-Ming Yin, Tamotsu Yoshimori, Zhenyu Yue, Michisuke Yuzaki, Olga Zabirnyk, Xiaoxiang Zheng, Xiongwei Zhu and Russell L. Deter
Volume: 4 | Issue: 2 | Pages: 151 - 175

Research Paper

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

Anne Simonsen, Robert C. Cumming, Andreas Brech, Pauline Isakson, David R. Schubert and Kim D. Finley
Volume: 4 | Issue: 2 | Pages: 176 - 184

Macroautophagy-dependent, intralysosomal cleavage of a betaine homocysteine methyltransferase fusion protein requires stable multimerization

Carol A. Mercer, Alagammai Kaliappan and Patrick B. Dennis
Volume: 4 | Issue: 2 | Pages: 185 - 194

Open Access Article

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3

Meghan B. Azad, Yongqiang Chen, Elizabeth S. Henson, Jeannick Cizeau, Eileen McMillan-Ward, Sara J. Israels and Spencer B. Gibson
Volume: 4 | Issue: 2 | Pages: 195 - 204

Rosella: A fluorescent pH-biosensor for reporting vacuolar turnover of cytosol and organelles in yeast

Carlos Rosado, Dalibor Mijaljica, Irene Hatzinisiriou, Mark Prescott and Rodney J. Devenish
Volume: 4 | Issue: 2 | Pages: 205 - 213

An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid

Yan Wang, Rong Han, Zhong-Qin Liang, Jun-Chao Wu, Xing-Ding Zhang, Zhen-Lun Gu and Zheng-Hong Qin
Volume: 4 | Issue: 2 | Pages: 214 - 226

Article Addendum

Upregulation of Beclin 1 in the ischemic penumbra

Abdelhaq Rami
Volume: 4 | Issue: 2 | Pages: 227 - 229

Roles of ESCRT in autophagy-associated neurodegeneration

Jin-A Lee and Fen-Biao Gao
Volume: 4 | Issue: 2 | Pages: 230 - 232

Open Access Article

ESCRTing autophagic clearance of aggregating proteins

Tor Erik Rusten, Maria Filimonenko, Lina M. Rodahl, Harald Stenmark and Anne Simonsen
Volume: 4 | Issue: 2 | Pages: 233 - 236

HspB8 and Bag3: A new chaperone complex targeting misfolded proteins to macroautophagy

Serena Carra, Samuel J. Seguin and Jacques Landry
Volume: 4 | Issue: 2 | Pages: 237 - 239

Cell death in fetal oocytes: Many players for multiple pathways

Massimo De Felici, Anna Maria Lobascio and Francesca Gioia Klinger
Volume: 4 | Issue: 2 | Pages: 240 - 242

Transport of autophagosomes in neurites of PC12 cells during serum deprivation

Yi Yang, Kedi Xu, Tatsuro Koike and Xiaoxiang Zheng
Volume: 4 | Issue: 2 | Pages: 243 - 245

Is mitochondrial generation of reactive oxygen species a trigger for autophagy?

Yongqiang Chen and Spencer B. Gibson
Volume: 4 | Issue: 2 | Pages: 246 - 248

Inducing autophagy harmlessly

Junying Yuan
Volume: 4 | Issue: 2 | Pages: 249 - 250

Lysine 63-linked polyubiquitin potentially partners with p62 to promote the clearance of protein inclusions by autophagy

Jeanne M.M Tan, Esther S.P. Wong, Valina L. Dawson, Ted Dawson and Kah-Leong Lim
Volume: 4 | Issue: 2 | Pages: 251 - 253

Autophagy as a second level protective process in conferring resistance to environmentally-induced oxidative stress

Michael N. Moore
Volume: 4 | Issue: 2 | Pages: 254 - 256

Views and Commentaries

To be or not to be? Examples of incorrect identification of autophagic compartments in conventional transmission electron microscopy of mammalian cells

Eeva-Liisa Eskelinen
Volume: 4 | Issue: 2 | Pages: 257 - 260