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Table of Contents

November/December 2007

volume 3| issue 6



Editor's Corner

Forward to the Past

Daniel J. Klionsky
Volume: 3 | Issue: 6 | Page 541

Open Access Article



Review

How to Interpret LC3 Immunoblotting

Noboru Mizushima and Tamotsu Yoshimori
Volume: 3 | Issue: 6 | Pages: 542 - 545

Open Access Article



Research Paper

Deconstructing Pompe Disease by Analyzing Single Muscle Fibers: “To See a World in a Grain of Sand…”

Nina Raben, Shoichi Takikita, Maria G. Pittis, Bruno Bembi, Suely K.N. Marie, Ashley Roberts, Laura Page, Priya S. Kishnani, Benedikt G.H. Schoser, Yin-Hsiu Chien, Evelyn Ralston, Kanneboyina Nagaraju and Paul H. Plotz
Volume: 3 | Issue: 6 | Pages: 546 - 552

Open Access Article


Cytosolic LC3 Ratio as a Sensitive Index of Macroautophagy in Isolated Rat Hepatocytes and H4-II-E Cells

Md. Razaul Karim, Takumi Kanazawa, Yasuhiro Daigaku, Shinobu Fujimura, Giovanni Miotto and Motoni Kadowaki
Volume: 3 | Issue: 6 | Pages: 553 - 560

Open Access Article


Differential Interactions Between Beclin 1 and Bcl-2 Family Members

Shlomit Erlich, Liat Mizrachy, Oshik Segev, Liora Lindenboim, Ofir Zmira, Sheli Adi-Harel, Joel A. Hirsch, Reuven Stein and Ronit Pinkas-Kramarski
Volume: 3 | Issue: 6 | Pages: 561 - 568

Open Access Article


Decreased Insulin-Receptor Signaling Promotes the Autophagic Degradation of β-Amyloid Peptide in C. elegans

Maria L. Florez-McClure, Lindsay A. Hohsfield, Gin Fonte, Matthew T. Bealor and Christopher D. Link
Volume: 3 | Issue: 6 | Pages: 569 - 580

Open Access Article


Coronavirus Replication Does Not Require the Autophagy Gene ATG5

Zijiang Zhao, Larissa B. Thackray, Brian C. Miller, Teresa M. Lynn, Michelle M. Becker, Eric Ward, Noboru Mizushima, Mark R. Denison and Herbert W. Virgin
Volume: 3 | Issue: 6 | Pages: 581 - 585

Open Access Article


Non-Autophagic GFP-LC3 Puncta Induced by Saponin and Other Detergents

Iwona A. Ciechomska and Aviva M. Tolkovsky
Volume: 3 | Issue: 6 | Pages: 586 - 590

Open Access Article


Aberrant Membranes and Double-Membrane Structures Accumulate in the Axons of Atg5-Null Purkinje Cells before Neuronal Death

Jun Nishiyama, Eriko Miura, Noboru Mizushima, Masahiko Watanabe and Michisuke Yuzaki
Volume: 3 | Issue: 6 | Pages: 591 - 596

Open Access Article



Brief Report

Autophagy is Required for Dietary Restriction-Mediated Life Span Extension in C. elegans

Kailiang Jia and Beth Levine
Volume: 3 | Issue: 6 | Pages: 597 - 599

Open Access Article



Article Addendum

Targeting Autophagic Regulation of NF-kappaB in HTLV-I Transformed Cells by Geldanamycin: Implications for Therapeutic Interventions

Pengrong Yan, Guoliang Qing, Zhaoxia Qu, Chang-Chih Wu, Arnold Rabson and Gutian Xiao
Volume: 3 | Issue: 6 | Pages: 600 - 603

Open Access Article


Overexpression of Autophagy-Related Genes Inhibits Yeast Filamentous Growth

Jun Ma, Rui Jin, Craig J. Dobry, Sarah K. Lawson and Anuj Kumar
Volume: 3 | Issue: 6 | Pages: 604 - 609

Open Access Article


Role of Autophagy in Breast Cancer

Vassiliki Karantza-Wadsworth and Eileen White
Volume: 3 | Issue: 6 | Pages: 610 - 613

Open Access Article


Increased Autophagic Degradation of Mitochondria in Alzheimer Disease

Paula I. Moreira, Sandra L. Siedlak, Xinglong Wang, Maria S. Santos, Catarina R. Oliveira, Massimo Tabaton, Akihiko Nunomura, Luke I. Szweda, Gjumrakch Aliev, Mark A. Smith, Xiongwei Zhu and George Perry
Volume: 3 | Issue: 6 | Pages: 614 - 615

Open Access Article


Regulation of Mitochondrial Integrity, Autophagy and Cell Survival by BNIP3

Kristin Tracy and Kay F. Macleod
Volume: 3 | Issue: 6 | Pages: 616 - 619

Open Access Article


Small Molecule Enhancers of Rapamycin-Induced TOR Inhibition Promote Autophagy, Reduce Toxicity in Huntington’s Disease Models and Enhance Killing of Mycobacteria by Macrophages

R. Andres Floto, Sovan Sarkar, Ethan O. Perlstein, Beate Kampmann, Stuart L. Schreiber and David C. Rubinsztein
Volume: 3 | Issue: 6 | Pages: 620 - 622

Open Access Article


Tipping the Delicate Balance: Defining How Proteasome Maturation Affects the Degradation of a Substrate for Autophagy and Endoplasmic Reticulum Associated Degradation (ERAD)

Jeffrey L. Brodsky and Craig M. Scott
Volume: 3 | Issue: 6 | Pages: 623 - 625

Open Access Article


Dihydroxyacetone Induced Autophagy in African Trypanosomes

Néstor L. Uzcátegui, Viola Denninger, Patrick Merkel, Caroline Schoenfeld, Katherine Figarella and Michael Duszenko
Volume: 3 | Issue: 6 | Pages: 626 - 629

Open Access Article


Lepidopteran Larval Midgut During Prepupal Instar: Digestion or Self-Digestion?

Gianluca Tettamanti, Annalisa Grimaldi, Francesco Pennacchio and Magda de Eguileor
Volume: 3 | Issue: 6 | Pages: 630 - 631

Open Access Article


Myocyte Autophagy in Heart Disease: Friend or Foe?

Beverly A. Rothermel and Joseph A. Hill
Volume: 3 | Issue: 6 | Pages: 632 - 634

Open Access Article


Roles of the Akt/mTOR/p70S6K and ERK1/2 Signaling Pathways in Curcumin-Induced Autophagy

Naoki Shinojima, Tomohisa Yokoyama, Yasuko Kondo and Seiji Kondo
Volume: 3 | Issue: 6 | Pages: 635 - 637

Open Access Article


A Novel Vacuolar Myopathy with Dilated Cardiomyopathy

Seiichiro Sugimoto
Volume: 3 | Issue: 6 | Pages: 638 - 639

Open Access Article


Gtdap-1 and the Role of Autophagy During Planarian Regeneration and Starvation

Cristina González-Estévez, Daniel A. Felix, Aziz A. Aboobaker and Emili Saló
Volume: 3 | Issue: 6 | Pages: 640 - 642

Open Access Article


HDAC6 at the Intersection of Autophagy, the Ubiquitin-proteasome System, and Neurodegeneration

Udai Bhan Pandey, Yakup Batlevi, Eric H. Baehrecke and J. Paul Taylor
Volume: 3 | Issue: 6 | Pages: 643 - 645

Open Access Article


Autophagic-Lysosomal Dysfunction and Neurodegeneration in Niemann-Pick Type C Mice: Lipid Starvation or Indigestion?

Xiaoning Bi and Guanghong Liao
Volume: 3 | Issue: 6 | Pages: 646 - 648

Open Access Article


Genome-wide Association Scanning Highlights Two Autophagy Genes, ATG16L1 and IRGM, as Being Significantly Associated with Crohn’s Disease

Dunecan C.O. Massey and Miles Parkes
Volume: 3 | Issue: 6 | Pages: 649 - 651

Open Access Article


Tocotrienols: Balancing the Mitochondrial Crosstalk Between Apoptosis and Autophagy

Eva C. Vaquero, Mariana Rickmann and Xavier Molero
Volume: 3 | Issue: 6 | Pages: 652 - 654

Open Access Article



Views and Commentaries

Sequestration Revisited: Integrating Traditional Electron Microscopy, De Novo Assembly and New Results

Attila L. Kovács, Zsolt Pálfia, Gábor Réz, Tibor Vellai and János Kovács
Volume: 3 | Issue: 6 | Pages: 655 - 662

Open Access Article


Beclin 1-Independent Pathway of Damage-Induced Mitophagy and Autophagic Stress: Implications for Neurodegeneration and Cell Death

Charleen T. Chu, Jianhui Zhu and Ruben K. Dagda
Volume: 3 | Issue: 6 | Pages: 663 - 667

Open Access Article


Identifying Atg1 Substrates: Four Means to an End

Stephen J. Deminoff and Paul K. Herman
Volume: 3 | Issue: 6 | Pages: 667 - 673

Open Access Article



Erratum

Autophagy in a Mouse Model of Distal Myopathy with Rimmed Vacuoles or Hereditary Inclusion Body Myopathy

May Christine V. Malicdan, Satoru Noguchi and Ichizo Nishino
Volume: 3 | Issue: 6 | Page 674

Open Access Article