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Article Addendum
Autophagy and Apoptosis Coordinate Physiological Cell Death in Larval Salivary Glands of Apis mellifera (Hymenoptera: Apidae)
Elaine C.M. Silva-Zacarin
volume 3 | issue 5
September/October 2007Pages: 516 - 518
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Larval salivary glands of bees provide a good model for the study of hormone-induced programmed cell death in Hymenoptera because they have a well-defined secretory cycle with a peak of secretory activity phase, prior to cocoon spinning, and a degenerative phase, after the cocoon spinning. Our findings demonstrate that there is a relationship between apoptosis and autophagy during physiological cell death in these larval salivary glands, that adds evidence to the hypothesis of overlap in the regulation pathways of both types of programmed cell death. Features of authophagy include cytoplasm vacuolation, acid phosphatase activity, presence of autophagic vacuoles and multi-lamellar structures, as well as a delay in the collapse of many nuclei. Features of apoptosis include bleb formation in the cytoplasm and nuclei, with release of parts of the cytoplasm into the lumen, chromatin compaction, and DNA and nucleolar fragmentation. We propose a model for programmed cell death in larval salivary glands of Apis mellifera where autophagy and apoptosis function cooperatively for a more efficient degeneration of the gland secretory cells.
Addendum to:
Programmed Cell Death in the Larval Salivary Glands of Apis mellifera (Hymenoptera, Apidae)
E.C.M. Silva-Zacarin, G.A. Tomaino, M.R. Brochetto-Braga, S.R. Taboga, R.L.M. Silva de Moraes
J Biosci 2007; 32:309-28
Authors
Elaine C.M. Silva-Zacarin
Universidade Federal de São Carlos
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.