Sign up for Table of Contents Alerts!
Email this page
Print this page
Views and Commentaries
Macroautophagy: Protector in the Diabetes Drama?
Alfred J. Meijer and Patrice Codogno
volume 3 | issue 5
September/October 2007Pages: 523 - 526
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.
Macroautophagy (“autophagy”) is regulated by the same insulin-amino acid-mTOR signaling pathway that controls protein synthesis. Although the literature does not so far include any direct studies confirming this, we expect autophagy to increase during insulin resistance. We discuss the possibility that this may be a useful mechanism for eliminating damaged mitochondria and other cell structures to prevent cell death.
Authors
Alfred J. Meijer
Academic Medical Center
Patrice Codogno
INSERM U756
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.