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Article Addendum
Caloric Restriction and Autophagy in Caenorhabditis elegans
Catarina Mörck and Marc Pilon
volume 3 | issue 1
January/February 2007Pages: 51 - 53
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Autophagy is a catabolic process in which long-lived proteins and organelles are degraded for recycling in the cytoplasm. In the nematode Caenorhabditis elegans autophagy is associated with formation of the dauer larva, an alternative developmental stage that worms can enter under poor growth conditions. We have shown that C. elegans mutants that experience caloric restriction because they are feeding-defective also exhibit elevated autophagy and decreased levels of fat deposits, as well as smaller cells and, consequently, a smaller body size. Our results suggest novel relationships between caloric restriction, longevity, body size and autophagy.
Addendum to:
C. elegans Feeding Defective Mutants Have Shorter Body Lengths and Increased Autophagy
C. Mörck and M. Pilon
BMC Dev Biol 2006; 6:39
Authors
Catarina Mörck
Göteborg University
Marc Pilon
Göteborg University
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.