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Article Addendum
Atg11 Directs Autophagosome Cargoes to the PAS Along Actin Cables
Iryna Monastyrska, Takahiro Shintani, Daniel J. Klionsky and Fulvio Reggiori
volume 2 | issue 2
April/May/June 2006Pages: 119 - 121
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For more than 40 years, autophagy has been almost exclusively studied as a cellular response that allows adaptation to starvation situations. In nutrient-deprived conditions, cytoplasmic components and organelles are randomly sequestered into double-membrane vesicles called autophagosomes, creating the notion that this pathway is a nonselective process. Recent results, however, have demonstrated that under certain circumstances, cargoes such as protein complexes, organelles and bacteria can be selectively and exclusively incorporated into double-membrane vesicles. We have recently shown that actin plays an essential role in two selective types of autophagy in the yeast
Addendum to:
The Actin Cytoskeleton is Required for Selective Types of Autophagy, but not Non-Specific Autophagy, in the Yeast
F. Reggiori, I. Monastryrska, T. Shintani and D.J. Klionsky
Mol Biol Cell 2005; In press.
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.