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Esteban Domingo

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ISBN: 978-1-58706-077-9
Pub date: 2000-12-01
221 pages
44 figures
15 tables

About this book

This book focuses on a new aspect of RNA virology: the highly dynamic, heterogeneous and plastic nature of RNA viruses which comprise more than 75% of the viruses that have been recognized as disease agents. It is the first attempt to bridge the gap from the basic, theoretical formulations underlying error-prone replications and generation of quasispecies, to their impact on how RNA viruses adapt and cause disease.

Table of contents

Introduction

Multiplication Strategies of RNA Genetic Elements

Molecular Recognition and Replication Enzymes

Quantitative Molecular

Darwinian Evolution of RNA in Vitro

Experimental Studies on Viral Quasispecies

Population Dynamics and Virus Adaptability

Connections, Implications and Prospects