Molecular Mechanisms
of Spondylorthropathies
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Carlos López-Larrea
This book will be published in
December of 2008 |
Table of contents
Planned List of Topics General Overview Clinical assessment in the spondyloarthropathies Imaging in SpA and AS The enthesitis organ concept and SpA disorders The role of Anti-TNF therapy in SpA Biomarkers for monitoring immunotherapy in AS Synovial and mucosal immunopathology in SpA HLA-B27 diversity and AS Genome wide-screen in AS HLA-B27: Structural and pathogenic issues HLA-B27, peptides and AS Biochemical features of HLA-B27 and antigen processing B27 misfolding and AS Animal models of SpA Dendritic cell: T cell interactions in spondyloarthritis HLA-B27 and host-microbe interaction T cell responses against viral and self-antigens Osteoclast precursor in SpA RANKL/RANK as key factors for osteoclast development Bone formation vs. bone resorption in AS KIR receptors, B27 diversity and disease NK receptor, HLA-B27 recognition and SpA Innate immunity of disease: Toll-like receptors and SpA |
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