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Jörg Reichrath
The Saarland University Hospital, Homburg, Germany

About this book

The goal of this volume is to comprehensively cover a highly readable overview on our present knowledge of positive and negative effects of UV-exposure, with a focus on vitamin D and skin cancer. Topics that are discussed in-depth by leading researchers and clinicians range from the newest findings in endocrinology, epidemiology, histology, photobiology, immunology, cytogenetics and molecular pathology to new concepts for prophylaxis and treatment. Experts in the field as well as health care professionals not intimately involved in these specialized areas are provided with the most significant and timely information related to these topics. It is the aim of this book to summarize essential up-to-date information for every clinician or scientist interested in how to balance between positive and negative effects of UV-exposure to minimize the risks of developing vitamin D deficiency and skin cancer.

Table of contents

1. Sunlight, UV-Radiation, Vitamin D and Skin Cancer:
How Much Sunlight Do We Need?
Michael F. Holick

2. Solar Ultraviolet Irradiance and Cancer Incidence and Mortality
William B. Grant

3. Vitamin D Status and Cancer Incidence and Mortality
Edward Giovannucci

4. Sun Exposure and Cancer Survival in Norway: Changes in the Risk of Death
with Season of Diagnosis and Latitude
Alina Carmen Porojnicu, Arne Dahlback and Johan Moan

5. Optimal Serum 25-Hydroxy vitamin D Levels for Multiple Health Outcomes
Heike A. Bischoff-Ferrari

6. Ultraviolet Exposure Scenarios: Risks of Erythema from Recommendations
on Cutaneous Vitamin D Synthesis
Ann R. Webb and Ola Engelsen

7. At What Time Should One Go Out in the Sun?
Johan Moan, Arne Dahlback and Alina Carmen Porojnicu

8. Epidemiology of Melanoma and Nonmelanoma Skin Cancer–The Role of Sunlight
Ulrike Leiter and Claus Garbe

9. Ultraviolet Radiation and Malignant Melanoma
Johan Moan, Alina Carmen Porojnicu and Arne Dahlback

10. Solar UV Exposure and Mortality from Skin Tumors
Marianne Berwick, Anne Lachiewicz, Claire Pestak and Nancy Thomas

11. Health Initiatives for the Prevention of Skin Cancer
Rüdiger Greinert, Eckhard W. Breitbart, Peter Mohr and Beate Volkmer

12. Sunscreens
Guido Bens

13. UV Damage and DNA Repair in Malignant Melanoma and Nonmelanoma
Skin Cancer
Knuth Rass and Jörg Reichrath

14. Role of Viruses in the Development of Squamous Cell Cancer and Melanoma
Ulrich R. Hengge

15. Melanoma and Nonmelanoma Skin Cancers and the Immune System
Diana Santo Domingo and Elma D. Baron

16. Solar UV-Radiation, Vitamin D and Skin Cancer Surveillance in Organ Transplant Recipients (OTRs)
Jörg Reichrath and Bernd Nürnberg

17. Histology of Melanoma and Nonmelanoma Skin Cancer
Cornelia S.L. Mueller and Jörg Reichrath

18. Cytogenetics of Melanoma and Nonmelanoma Skin Cancer
Melanie A. Carless and Lyn R. Griffiths

19. Molecular Biology of Basal and Squamous Cell Carcinomas
Jingwu Xie

20. Molecular Biology of Malignant Melanoma
Mar Pons, Pablo Mancheño-Corvo, Pilar Martín-Duque and Miguel Quintanilla

21. p53 Protein and Pathogenesis of Melanoma and Nonmelanoma Skin Cancer
Cara L. Benjamin, Vladislava O. Melnikova and Honnavara N. Ananthaswamy

22. Apoptosis and Pathogenesis of Melanoma and Nonmelanoma Skin Cancer
Peter Erb, Jingmin Ji, Erwin Kump, Ainhoa Mielgo and Marion Wernli

23. Treatment of Melanoma and Nonmelanoma Skin Cancer
Knuth Rass and Wolfgang Tilgen